This is the analysis script to prepare the data to run analyses for the project “Anxiety, depression and trauma symptom change during the COVID-19 pandemic: retrospective versus objective assessment” - Young et al (2020)
Script written by K L Purves, K N Thompson, C Huebel and M Davies. Email: kirstin.purves@kcl.ac.uk, katie.thompson@kcl.ac.uk, christopher.1.huebel@kcl.ac.uk, molly.davies@kcl.ac.uk
#Set up
Clear global environment
Retrieve the current date to use it for file endings to not overwrite files when one exports files
#Packages Install packages (if they are not available in your version of R)
Load packages
Registered S3 method overwritten by 'pryr':
method from
print.bytes Rcpp
For best results, restart R session and update pander using devtools:: or remotes::install_github('rapporter/pander')
Attaching package: 'polycor'
The following object is masked from 'package:psych':
polyserial
corrplot 0.84 loaded
── Attaching packages ─────────────────────────────────────── tidyverse 1.3.0 ──
✓ ggplot2 3.3.2 ✓ purrr 0.3.4
✓ tibble 3.0.4 ✓ dplyr 1.0.2
✓ tidyr 1.1.2 ✓ stringr 1.4.0
✓ readr 1.3.1 ✓ forcats 0.5.0
── Conflicts ────────────────────────────────────────── tidyverse_conflicts() ──
x ggplot2::%+%() masks psych::%+%()
x ggplot2::alpha() masks psych::alpha()
x dplyr::filter() masks stats::filter()
x dplyr::lag() masks stats::lag()
x tibble::view() masks summarytools::view()
R functions
Half-violin plot
Colour palettes
Define colours for plotting this are the standard coping colours
Choose in this chunk which palette to use 04.07.2020 - Default to 2 colour COPING palette
ggplot theme
Set up ggplot theme for the plots
Function for split violin plot
Data import
Source data file paths
[1] "/Users/kirstin/King's College London/MT-TNG BioResource EDIT - COPING_analysis - COPING_analysis/PANCHANGE/data/"
Read in data
[1] 31884 641
[1] "Sample"
[2] "ID"
[3] "startDate.prepandemic"
[4] "Age_uncleaned"
[5] "Gender_unc"
[6] "Sex"
[7] "EduYrs"
[8] "demographics.college_or_university_degree"
[9] "demographics.a_levelsas_levels_or_equivalent"
[10] "demographics.o_levelsgcses_or_equivalent"
[11] "demographics.cses_or_equivalent"
[12] "demographics.nvq_or_hnd_or_hnc_or_equivalent"
[13] "Ethnicity_unc"
[14] "Gender_numeric"
[15] "Sex_numeric"
[16] "demographics.college_or_university_degree_numeric"
[17] "demographics.a_levelsas_levels_or_equivalent_numeric"
[18] "demographics.o_levelsgcses_or_equivalent_numeric"
[19] "demographics.cses_or_equivalent_numeric"
[20] "demographics.nvq_or_hnd_or_hnc_or_equivalent_numeric"
[21] "Ethnicity_numeric"
[22] "Gender"
[23] "Ethnicity"
[24] "Age"
[25] "age_category_numeric"
[26] "age_category"
[27] "highest_education_prepan_numeric"
[28] "highest_education_prepan"
[29] "employment.phd"
[30] "employment.masters_degree_or_equivalent"
[31] "employment.postgraduate_degree_or_equivalent"
[32] "employment.bachelors_degree_or_equivalent"
[33] "employment.a_levelsas_levels_or_equivalent"
[34] "employment.o_levelsgcses_or_equivalent"
[35] "employment.cses_or_equivalent"
[36] "employment.nvq_or_hnd_or_hnc_or_equivalent"
[37] "employment.government_work_key_workers"
[38] "employment.unemployed"
[39] "employment.zerohours_contract"
[40] "employment.stayathome_parent_or_carer"
[41] "employment.retired"
[42] "employment.student_gcse_or_a_level"
[43] "employment.student_university"
[44] "employment.became_unemployed"
[45] "employment.furloughed_or_paid_leave_government_funded"
[46] "employment.furloughed_or_paid_leave_company_funded"
[47] "employment.paid_leave_furloughed"
[48] "employment.fulltime_employed"
[49] "employment.parttime_employed"
[50] "employment.selfemployed"
[51] "employment.contract_or_freelance_work"
[52] "employment.small_business_owner"
[53] "employment.receiving_state_income"
[54] "employment.my_employment_status_has_not_changed"
[55] "employment.reduction_in_hours"
[56] "employment.reduction_in_salary"
[57] "employment.benefits_increased"
[58] "employment.benefits_decreased"
[59] "employment.became_employed"
[60] "employment.increased_hours"
[61] "employment.increased_salary"
[62] "employment.phd_numeric"
[63] "employment.masters_degree_or_equivalent_numeric"
[64] "employment.postgraduate_degree_or_equivalent_numeric"
[65] "employment.bachelors_degree_or_equivalent_numeric"
[66] "employment.a_levelsas_levels_or_equivalent_numeric"
[67] "employment.o_levelsgcses_or_equivalent_numeric"
[68] "employment.cses_or_equivalent_numeric"
[69] "employment.nvq_or_hnd_or_hnc_or_equivalent_numeric"
[70] "employment.government_work_key_workers_numeric"
[71] "employment.unemployed_numeric"
[72] "employment.zerohours_contract_numeric"
[73] "employment.stayathome_parent_or_carer_numeric"
[74] "employment.retired_numeric"
[75] "employment.student_gcse_or_a_level_numeric"
[76] "employment.student_university_numeric"
[77] "employment.became_unemployed_numeric"
[78] "employment.furloughed_or_paid_leave_government_funded_numeric"
[79] "employment.furloughed_or_paid_leave_company_funded_numeric"
[80] "employment.paid_leave_furloughed_numeric"
[81] "employment.fulltime_employed_numeric"
[82] "employment.parttime_employed_numeric"
[83] "employment.selfemployed_numeric"
[84] "employment.contract_or_freelance_work_numeric"
[85] "employment.small_business_owner_numeric"
[86] "employment.receiving_state_income_numeric"
[87] "employment.my_employment_status_has_not_changed_numeric"
[88] "employment.reduction_in_hours_numeric"
[89] "employment.reduction_in_salary_numeric"
[90] "employment.benefits_increased_numeric"
[91] "employment.benefits_decreased_numeric"
[92] "employment.became_employed_numeric"
[93] "employment.increased_hours_numeric"
[94] "employment.increased_salary_numeric"
[95] "highest_education_numeric"
[96] "highest_education"
[97] "employment_prior_covid_numeric"
[98] "employment_prior_covid"
[99] "employment_change_numeric"
[100] "employment_change"
[101] "key_worker_numeric"
[102] "key_worker"
[103] "anxiety_disorders_numeric"
[104] "anxiety_disorders"
[105] "mhd.specific_phobia_e.g._phobia_of_flying_numeric"
[106] "mhd.specific_phobia_e.g._phobia_of_flying"
[107] "mhd.social_anxiety_or_social_phobia_numeric"
[108] "mhd.social_anxiety_or_social_phobia"
[109] "agoraphobia_panic_disorder_numeric"
[110] "agoraphobia_panic_disorder"
[111] "depressive_disorders_numeric"
[112] "depressive_disorders"
[113] "eating_disorders_numeric"
[114] "eating_disorders"
[115] "obsessive_compulsive_disorders_numeric"
[116] "obsessive_compulsive_disorders"
[117] "psychotic_disorders_numeric"
[118] "psychotic_disorders"
[119] "mhd.mania_hypomania_bipolar_or_manicdepression_numeric"
[120] "mhd.mania_hypomania_bipolar_or_manicdepression"
[121] "mhd.posttraumatic_stress_disorder_ptsd_numeric"
[122] "mhd.posttraumatic_stress_disorder_ptsd"
[123] "autism_spectrum_disorder_numeric"
[124] "autism_spectrum_disorder"
[125] "mhd.attention_deficit_hyperactivity_disorder_numeric"
[126] "mhd.attention_deficit_hyperactivity_disorder"
[127] "mhd.personality_disorder_numeric"
[128] "mhd.personality_disorder"
[129] "personality_cluster_a_numeric"
[130] "personality_cluster_a"
[131] "personality_cluster_b_numeric"
[132] "personality_cluster_b"
[133] "personality_cluster_c_numeric"
[134] "personality_cluster_c"
[135] "depression_and_anxiety_numeric"
[136] "depression_and_anxiety"
[137] "restricting_vs_binge_eating_eating_disorders_numeric"
[138] "restricting_vs_binge_eating_eating_disorders"
[139] "bipolar_and_schizophrenia_numeric"
[140] "bipolar_and_schizophrenia"
[141] "control_numeric"
[142] "control"
[143] "disorders_total_count"
[144] "comorbidity_total_count_numeric"
[145] "comorbidity_total_count_factor_numeric"
[146] "comorbidity_total_count_factor"
[147] "mhd.none_of_the_above"
[148] "mhd.none_of_the_above.1"
[149] "gad.feeling_nervous_anxious_or_on_edge_prepan"
[150] "gad.control_worrying_stop_prepan"
[151] "gad.worrying_too_much_about_different_things_prepan"
[152] "gad.trouble_relaxing_prepan"
[153] "gad.sit_restless_hard_prepan"
[154] "gad.becoming_easily_annoyed_or_irritable_prepan"
[155] "gad.awful_feeling_afraid_happen_prepan"
[156] "gad.feeling_nervous_anxious_or_on_edge_prepan_numeric"
[157] "gad.control_worrying_stop_prepan_numeric"
[158] "gad.worrying_too_much_about_different_things_prepan_numeric"
[159] "gad.trouble_relaxing_prepan_numeric"
[160] "gad.sit_restless_hard_prepan_numeric"
[161] "gad.becoming_easily_annoyed_or_irritable_prepan_numeric"
[162] "gad.awful_feeling_afraid_happen_prepan_numeric"
[163] "gad.sum_score_prepan_raw"
[164] "na_per_person_gad_prepan"
[165] "gad.sum_score_prepan"
[166] "pcl.stressful_experience_repeated_images_prepan"
[167] "pcl.stressful_experience_upset_reminded_prepan"
[168] "pcl.stressful_situation_avoiding_activities_prepan"
[169] "pcl.cut_people_feeling_distant_prepan"
[170] "pcl.feeling_irritable_or_having_angry_outbursts_prepan"
[171] "pcl.difficulty_concentrating_prepan"
[172] "pcl.stressful_experience_repeated_images_prepan_numeric"
[173] "pcl.stressful_experience_upset_reminded_prepan_numeric"
[174] "pcl.stressful_situation_avoiding_activities_prepan_numeric"
[175] "pcl.cut_people_feeling_distant_prepan_numeric"
[176] "pcl.feeling_irritable_or_having_angry_outbursts_prepan_numeric"
[177] "pcl.difficulty_concentrating_prepan_numeric"
[178] "pcl.sum_score_prepan_raw"
[179] "na_per_person_pcl_prepan"
[180] "pcl.sum_score_prepan"
[181] "phq.little_interest_or_pleasure_in_doing_things_prepan"
[182] "phq.feeling_down_depressed_or_hopeless_prepan"
[183] "phq.staying_asleep_sleeping_trouble_prepan"
[184] "phq.feeling_tired_or_having_little_energy_prepan"
[185] "phq.poor_appetite_or_overeating_prepan"
[186] "phq.feeling_bad_failure_family_prepan"
[187] "phq.trouble_concentrating_reading_newspaper_prepan"
[188] "phq.moving_fidgety_noticed_opposite_prepan"
[189] "phq.dead_hurting_thoughts_prepan"
[190] "phq.little_interest_or_pleasure_in_doing_things_prepan_numeric"
[191] "phq.feeling_down_depressed_or_hopeless_prepan_numeric"
[192] "phq.staying_asleep_sleeping_trouble_prepan_numeric"
[193] "phq.feeling_tired_or_having_little_energy_prepan_numeric"
[194] "phq.poor_appetite_or_overeating_prepan_numeric"
[195] "phq.feeling_bad_failure_family_prepan_numeric"
[196] "phq.trouble_concentrating_reading_newspaper_prepan_numeric"
[197] "phq.moving_fidgety_noticed_opposite_prepan_numeric"
[198] "phq.dead_hurting_thoughts_prepan_numeric"
[199] "phq.sum_score_prepan_raw"
[200] "na_per_person_phq_prepan"
[201] "phq.missing_only_suicide_item_prepan"
[202] "phq.sum_score_prepan"
[203] "phq.sum_score_8items_prepan"
[204] "ocir.i_repeatedly_check_doors_windows_drawers_etc_prepan"
[205] "ocir.arranged_things_change_upset_prepan"
[206] "ocir.repeat_feel_numbers_prepan"
[207] "ocir.clean_simply_wash_feel_prepan"
[208] "ocir.mind_upset_unpleasant_thoughts_prepan"
[209] "ocir.afraid_avoid_throwing_things_prepan"
[210] "ocir.light_switches_water_taps_prepan"
[211] "ocir.arranged_things_prepan"
[212] "ocir.good_feel_bad_numbers_prepan"
[213] "ocir.hands_longer_wash_prepan"
[214] "ocir.saved_things_prepan"
[215] "ocir.frequently_difficulty_rid_nasty_prepan"
[216] "ocir.i_check_things_more_often_than_necessary_prepan"
[217] "ocir.arranged_properly_objects_upset_prepan"
[218] "ocir.feel_compelled_count_things_prepan"
[219] "ocir.strangers_touch_touched_difficult_prepan"
[220] "ocir.control_difficult_find_thoughts_prepan"
[221] "ocir.i_collect_things_i_dont_need_prepan"
[222] "ocir.i_repeatedly_check_doors_windows_drawers_etc_prepan_numeric"
[223] "ocir.arranged_things_change_upset_prepan_numeric"
[224] "ocir.repeat_feel_numbers_prepan_numeric"
[225] "ocir.clean_simply_wash_feel_prepan_numeric"
[226] "ocir.mind_upset_unpleasant_thoughts_prepan_numeric"
[227] "ocir.afraid_avoid_throwing_things_prepan_numeric"
[228] "ocir.light_switches_water_taps_prepan_numeric"
[229] "ocir.arranged_things_prepan_numeric"
[230] "ocir.good_feel_bad_numbers_prepan_numeric"
[231] "ocir.hands_longer_wash_prepan_numeric"
[232] "ocir.saved_things_prepan_numeric"
[233] "ocir.frequently_difficulty_rid_nasty_prepan_numeric"
[234] "ocir.i_check_things_more_often_than_necessary_prepan_numeric"
[235] "ocir.arranged_properly_objects_upset_prepan_numeric"
[236] "ocir.feel_compelled_count_things_prepan_numeric"
[237] "ocir.strangers_touch_touched_difficult_prepan_numeric"
[238] "ocir.control_difficult_find_thoughts_prepan_numeric"
[239] "ocir.i_collect_things_i_dont_need_prepan_numeric"
[240] "ocir.sum_score_prepan_raw"
[241] "na_per_person_ocir_prepan"
[242] "ocir.sum_score_prepan"
[243] "startDate.coping"
[244] "gad.problems_made_difficult_care"
[245] "gad.pandemic_felt_feelings"
[246] "gad.feeling_nervous_anxious_or_on_edge_retro"
[247] "gad.control_worrying_stop_retro"
[248] "gad.worrying_too_much_about_different_things_retro"
[249] "gad.trouble_relaxing_retro"
[250] "gad.sit_restless_hard_retro"
[251] "gad.becoming_easily_annoyed_or_irritable_retro"
[252] "gad.awful_feeling_afraid_happen_retro"
[253] "gad.feeling_nervous_anxious_or_on_edge_base"
[254] "gad.control_worrying_stop_base"
[255] "gad.worrying_too_much_about_different_things_base"
[256] "gad.trouble_relaxing_base"
[257] "gad.sit_restless_hard_base"
[258] "gad.becoming_easily_annoyed_or_irritable_base"
[259] "gad.awful_feeling_afraid_happen_base"
[260] "gad.problems_made_difficult_care_numeric"
[261] "gad.pandemic_felt_feelings_numeric"
[262] "gad.feeling_nervous_anxious_or_on_edge_retro_numeric"
[263] "gad.control_worrying_stop_retro_numeric"
[264] "gad.worrying_too_much_about_different_things_retro_numeric"
[265] "gad.trouble_relaxing_retro_numeric"
[266] "gad.sit_restless_hard_retro_numeric"
[267] "gad.becoming_easily_annoyed_or_irritable_retro_numeric"
[268] "gad.awful_feeling_afraid_happen_retro_numeric"
[269] "gad.feeling_nervous_anxious_or_on_edge_base_numeric"
[270] "gad.control_worrying_stop_base_numeric"
[271] "gad.worrying_too_much_about_different_things_base_numeric"
[272] "gad.trouble_relaxing_base_numeric"
[273] "gad.sit_restless_hard_base_numeric"
[274] "gad.becoming_easily_annoyed_or_irritable_base_numeric"
[275] "gad.awful_feeling_afraid_happen_base_numeric"
[276] "gad.sum_score_retro_raw"
[277] "gad.sum_score_base_raw"
[278] "na_per_person_gad_base"
[279] "na_per_person_gad_retro"
[280] "gad.sum_score_base"
[281] "gad.sum_score_retro"
[282] "pcl.stressful_experience_repeated_images_base"
[283] "pcl.stressful_experience_upset_reminded_base"
[284] "pcl.stressful_situation_avoiding_activities_base"
[285] "pcl.cut_people_feeling_distant_base"
[286] "pcl.feeling_irritable_or_having_angry_outbursts_base"
[287] "pcl.difficulty_concentrating_base"
[288] "pcl.stressful_experience_repeated_images_retro"
[289] "pcl.stressful_experience_upset_reminded_retro"
[290] "pcl.stressful_situation_avoiding_activities_retro"
[291] "pcl.cut_people_feeling_distant_retro"
[292] "pcl.feeling_irritable_or_having_angry_outbursts_retro"
[293] "pcl.difficulty_concentrating_retro"
[294] "pcl.stressful_experience_repeated_images_base_numeric"
[295] "pcl.stressful_experience_upset_reminded_base_numeric"
[296] "pcl.stressful_situation_avoiding_activities_base_numeric"
[297] "pcl.cut_people_feeling_distant_base_numeric"
[298] "pcl.feeling_irritable_or_having_angry_outbursts_base_numeric"
[299] "pcl.difficulty_concentrating_base_numeric"
[300] "pcl.stressful_experience_repeated_images_retro_numeric"
[301] "pcl.stressful_experience_upset_reminded_retro_numeric"
[302] "pcl.stressful_situation_avoiding_activities_retro_numeric"
[303] "pcl.cut_people_feeling_distant_retro_numeric"
[304] "pcl.feeling_irritable_or_having_angry_outbursts_retro_numeric"
[305] "pcl.difficulty_concentrating_retro_numeric"
[306] "pcl.sum_score_retro_raw"
[307] "pcl.sum_score_base_raw"
[308] "na_per_person_pcl_base"
[309] "na_per_person_pcl_retro"
[310] "pcl.sum_score_base"
[311] "pcl.sum_score_retro"
[312] "phq.problems_made_difficult_care"
[313] "phq.pandemic_felt_feelings"
[314] "phq.little_interest_or_pleasure_in_doing_things_retro"
[315] "phq.feeling_down_depressed_or_hopeless_retro"
[316] "phq.staying_asleep_sleeping_trouble_retro"
[317] "phq.feeling_tired_or_having_little_energy_retro"
[318] "phq.poor_appetite_or_overeating_retro"
[319] "phq.feeling_bad_failure_family_retro"
[320] "phq.trouble_concentrating_reading_newspaper_retro"
[321] "phq.moving_fidgety_noticed_opposite_retro"
[322] "phq.dead_hurting_thoughts_retro"
[323] "phq.little_interest_or_pleasure_in_doing_things_base"
[324] "phq.feeling_down_depressed_or_hopeless_base"
[325] "phq.staying_asleep_sleeping_trouble_base"
[326] "phq.feeling_tired_or_having_little_energy_base"
[327] "phq.poor_appetite_or_overeating_base"
[328] "phq.feeling_bad_failure_family_base"
[329] "phq.trouble_concentrating_reading_newspaper_base"
[330] "phq.moving_fidgety_noticed_opposite_base"
[331] "phq.dead_hurting_thoughts_base"
[332] "phq.problems_made_difficult_care_numeric"
[333] "phq.pandemic_felt_feelings_numeric"
[334] "phq.little_interest_or_pleasure_in_doing_things_retro_numeric"
[335] "phq.feeling_down_depressed_or_hopeless_retro_numeric"
[336] "phq.staying_asleep_sleeping_trouble_retro_numeric"
[337] "phq.feeling_tired_or_having_little_energy_retro_numeric"
[338] "phq.poor_appetite_or_overeating_retro_numeric"
[339] "phq.feeling_bad_failure_family_retro_numeric"
[340] "phq.trouble_concentrating_reading_newspaper_retro_numeric"
[341] "phq.moving_fidgety_noticed_opposite_retro_numeric"
[342] "phq.dead_hurting_thoughts_retro_numeric"
[343] "phq.little_interest_or_pleasure_in_doing_things_base_numeric"
[344] "phq.feeling_down_depressed_or_hopeless_base_numeric"
[345] "phq.staying_asleep_sleeping_trouble_base_numeric"
[346] "phq.feeling_tired_or_having_little_energy_base_numeric"
[347] "phq.poor_appetite_or_overeating_base_numeric"
[348] "phq.feeling_bad_failure_family_base_numeric"
[349] "phq.trouble_concentrating_reading_newspaper_base_numeric"
[350] "phq.moving_fidgety_noticed_opposite_base_numeric"
[351] "phq.dead_hurting_thoughts_base_numeric"
[352] "phq.sum_score_retro_raw"
[353] "phq.sum_score_base_raw"
[354] "na_per_person_phq_retro"
[355] "phq.missing_only_suicide_item_retro"
[356] "na_per_person_phq_base"
[357] "phq.missing_only_suicide_item_base"
[358] "phq.sum_score_base"
[359] "phq.sum_score_8items_base"
[360] "phq.sum_score_retro"
[361] "phq.sum_score_8items_retro"
[362] "ocir.felt_pandemic_feelings"
[363] "ocir.i_repeatedly_check_doors_windows_drawers_etc_retro"
[364] "ocir.arranged_things_change_upset_retro"
[365] "ocir.repeat_feel_numbers_retro"
[366] "ocir.clean_simply_wash_feel_retro"
[367] "ocir.mind_upset_unpleasant_thoughts_retro"
[368] "ocir.afraid_avoid_throwing_things_retro"
[369] "ocir.light_switches_water_taps_retro"
[370] "ocir.arranged_things_retro"
[371] "ocir.good_feel_bad_numbers_retro"
[372] "ocir.hands_longer_wash_retro"
[373] "ocir.saved_things_retro"
[374] "ocir.frequently_difficulty_rid_nasty_retro"
[375] "ocir.i_check_things_more_often_than_necessary_retro"
[376] "ocir.arranged_properly_objects_upset_retro"
[377] "ocir.feel_compelled_count_things_retro"
[378] "ocir.strangers_touch_touched_difficult_retro"
[379] "ocir.control_difficult_find_thoughts_retro"
[380] "ocir.i_collect_things_i_dont_need_retro"
[381] "ocir.i_repeatedly_check_doors_windows_drawers_etc_base"
[382] "ocir.arranged_things_change_upset_base"
[383] "ocir.repeat_feel_numbers_base"
[384] "ocir.clean_simply_wash_feel_base"
[385] "ocir.mind_upset_unpleasant_thoughts_base"
[386] "ocir.afraid_avoid_throwing_things_base"
[387] "ocir.light_switches_water_taps_base"
[388] "ocir.arranged_things_base"
[389] "ocir.good_feel_bad_numbers_base"
[390] "ocir.hands_longer_wash_base"
[391] "ocir.saved_things_base"
[392] "ocir.frequently_difficulty_rid_nasty_base"
[393] "ocir.i_check_things_more_often_than_necessary_base"
[394] "ocir.arranged_properly_objects_upset_base"
[395] "ocir.feel_compelled_count_things_base"
[396] "ocir.strangers_touch_touched_difficult_base"
[397] "ocir.control_difficult_find_thoughts_base"
[398] "ocir.i_collect_things_i_dont_need_base"
[399] "ocir.felt_pandemic_feelings_numeric"
[400] "ocir.i_repeatedly_check_doors_windows_drawers_etc_retro_numeric"
[401] "ocir.arranged_things_change_upset_retro_numeric"
[402] "ocir.repeat_feel_numbers_retro_numeric"
[403] "ocir.clean_simply_wash_feel_retro_numeric"
[404] "ocir.mind_upset_unpleasant_thoughts_retro_numeric"
[405] "ocir.afraid_avoid_throwing_things_retro_numeric"
[406] "ocir.light_switches_water_taps_retro_numeric"
[407] "ocir.arranged_things_retro_numeric"
[408] "ocir.good_feel_bad_numbers_retro_numeric"
[409] "ocir.hands_longer_wash_retro_numeric"
[410] "ocir.saved_things_retro_numeric"
[411] "ocir.frequently_difficulty_rid_nasty_retro_numeric"
[412] "ocir.i_check_things_more_often_than_necessary_retro_numeric"
[413] "ocir.arranged_properly_objects_upset_retro_numeric"
[414] "ocir.feel_compelled_count_things_retro_numeric"
[415] "ocir.strangers_touch_touched_difficult_retro_numeric"
[416] "ocir.control_difficult_find_thoughts_retro_numeric"
[417] "ocir.i_collect_things_i_dont_need_retro_numeric"
[418] "ocir.i_repeatedly_check_doors_windows_drawers_etc_base_numeric"
[419] "ocir.arranged_things_change_upset_base_numeric"
[420] "ocir.repeat_feel_numbers_base_numeric"
[421] "ocir.clean_simply_wash_feel_base_numeric"
[422] "ocir.mind_upset_unpleasant_thoughts_base_numeric"
[423] "ocir.afraid_avoid_throwing_things_base_numeric"
[424] "ocir.light_switches_water_taps_base_numeric"
[425] "ocir.arranged_things_base_numeric"
[426] "ocir.good_feel_bad_numbers_base_numeric"
[427] "ocir.hands_longer_wash_base_numeric"
[428] "ocir.saved_things_base_numeric"
[429] "ocir.frequently_difficulty_rid_nasty_base_numeric"
[430] "ocir.i_check_things_more_often_than_necessary_base_numeric"
[431] "ocir.arranged_properly_objects_upset_base_numeric"
[432] "ocir.feel_compelled_count_things_base_numeric"
[433] "ocir.strangers_touch_touched_difficult_base_numeric"
[434] "ocir.control_difficult_find_thoughts_base_numeric"
[435] "ocir.i_collect_things_i_dont_need_base_numeric"
[436] "ocir.sum_score_retro_raw"
[437] "ocir.sum_score_base_raw"
[438] "na_per_person_ocir_retro"
[439] "na_per_person_ocir_base"
[440] "ocir.sum_score_base"
[441] "ocir.sum_score_retro"
[442] "alsfrs.limb_weakness_noticed_past"
[443] "alsfrs.normal"
[444] "alsfrs.slow_or_sloppy_all_words_are_legible"
[445] "alsfrs.not_all_words_are_legible"
[446] "alsfrs.able_to_grip_pen"
[447] "alsfrs.unable_to_grip_pen"
[448] "alsfrs.have_you_noticed_any_difficulty_walking"
[449] "alsfrs.do_you_have_any_difficulty_climbing_stairs"
[450] "alsfrs.limb_weakness_noticed_past_numeric"
[451] "alsfrs.normal_numeric"
[452] "alsfrs.slow_or_sloppy_all_words_are_legible_numeric"
[453] "alsfrs.not_all_words_are_legible_numeric"
[454] "alsfrs.able_to_grip_pen_numeric"
[455] "alsfrs.unable_to_grip_pen_numeric"
[456] "alsfrs.have_you_noticed_any_difficulty_walking_numeric"
[457] "alsfrs.do_you_have_any_difficulty_climbing_stairs_numeric"
[458] "ess.felt_excessively_sleepy_past"
[459] "ess.sitting_and_reading"
[460] "ess.watching_tv"
[461] "ess.sitting_inactive_in_a_public_place"
[462] "ess.break_passenger_car_hour"
[463] "ess.afternoon_rest_circumstances_lying"
[464] "ess.sitting_and_talking_to_someone"
[465] "ess.sitting_quietly_after_a_lunch_without_alcohol"
[466] "ess.car_minutes_stopped_traffic"
[467] "ess.insomnia"
[468] "ess.narcolepsy"
[469] "ess.rem_sleep_behaviour_disorder"
[470] "ess.restless_legs_syndrome"
[471] "ess.sleep_apnea"
[472] "ess.sleep_terrors"
[473] "ess.sleepwalking"
[474] "ess.other"
[475] "ess.none"
[476] "ess.felt_excessively_sleepy_past_numeric"
[477] "ess.sitting_and_reading_numeric"
[478] "ess.watching_tv_numeric"
[479] "ess.sitting_inactive_in_a_public_place_numeric"
[480] "ess.break_passenger_car_hour_numeric"
[481] "ess.afternoon_rest_circumstances_lying_numeric"
[482] "ess.sitting_and_talking_to_someone_numeric"
[483] "ess.sitting_quietly_after_a_lunch_without_alcohol_numeric"
[484] "ess.car_minutes_stopped_traffic_numeric"
[485] "ess.insomnia_numeric"
[486] "ess.narcolepsy_numeric"
[487] "ess.rem_sleep_behaviour_disorder_numeric"
[488] "ess.restless_legs_syndrome_numeric"
[489] "ess.sleep_apnea_numeric"
[490] "ess.sleep_terrors_numeric"
[491] "ess.sleepwalking_numeric"
[492] "ess.other_numeric"
[493] "ess.none_numeric"
[494] "midas.headaches_suffered_past_month"
[495] "midas.days_past_month_miss_work_school"
[496] "midas.days_past_month_work_school_half_productivity"
[497] "midas.days_past_month_miss_housework"
[498] "midas.days_past_month_housework_half_productivity"
[499] "midas.days_past_month_miss_social_activities"
[500] "midas.headaches_suffered_past_month_numeric"
[501] "midas.days_past_month_miss_work_school_numeric"
[502] "midas.days_past_month_work_school_half_productivity_numeric"
[503] "midas.days_past_month_miss_housework_numeric"
[504] "midas.days_past_month_housework_half_productivity_numeric"
[505] "midas.days_past_month_miss_social_activities_numeric"
[506] "nmss.ability_taste_food_smell"
[507] "nmss.severe_taste_smell_loss"
[508] "nmss.ability_taste_food_smell_numeric"
[509] "nmss.severe_taste_smell_loss_numeric"
[510] "nmsw.drink_problems_choking_difficulty"
[511] "nmsw.regularly_night_pass_urine"
[512] "nmsw.sex_difficult_finding"
[513] "nmsw.weak_standing_feeling_light"
[514] "nmsw.acting_moving_sleep_talking"
[515] "nmsw.double_vision"
[516] "nmsw.drink_problems_choking_difficulty_numeric"
[517] "nmsw.regularly_night_pass_urine_numeric"
[518] "nmsw.sex_difficult_finding_numeric"
[519] "nmsw.weak_standing_feeling_light_numeric"
[520] "nmsw.acting_moving_sleep_talking_numeric"
[521] "nmsw.double_vision_numeric"
[522] "tinnitus.ears_noises_minutes_head"
[523] "tinnitus.ears_noises_minutes_head_frequency"
[524] "tinnitus.noises_worry_worst_upset"
[525] "tinnitus.ears_noises_minutes_head_numeric"
[526] "tinnitus.ears_noises_minutes_head_frequency_numeric"
[527] "tinnitus.noises_worry_worst_upset_numeric"
[528] "ID.dup"
[529] "prepandemic_january_31_numeric"
[530] "prepandemic_january_31"
[531] "prepandemic_march_1_numeric"
[532] "prepandemic_march_1"
[533] "prepandemic_march_23_numeric"
[534] "prepandemic_march_23"
[535] "time_diff_coping_lockdown_march_23"
[536] "time_diff_coping_awareness_march_1"
[537] "time_diff_coping_first_case_uk_jan_31"
[538] "time_diff_signup_lockdown_march_23"
[539] "time_diff_signup_awareness_march_1"
[540] "time_diff_signup_first_case_uk_jan_31"
[541] "time_diff_sign_up_coping"
[542] "phq.diff_score_retro_prepan"
[543] "phq.diff_score_base_prepan"
[544] "phq.diff_score_base_retro"
[545] "gad.diff_score_retro_prepan"
[546] "gad.diff_score_base_prepan"
[547] "gad.diff_score_base_retro"
[548] "pcl.diff_score_base_prepan"
[549] "ocir.diff_score_retro_prepan"
[550] "ocir.diff_score_base_prepan"
[551] "ocir.diff_score_base_retro"
[552] "data_group_phq_numeric"
[553] "data_group_phq"
[554] "data_group_gad_numeric"
[555] "data_group_gad"
[556] "data_group_pcl_numeric"
[557] "data_group_pcl"
[558] "data_group_ocir_numeric"
[559] "data_group_ocir"
[560] "respiratory.breath_diarrhoea_fatigue_fever"
[561] "respiratory.worst_ill_feel"
[562] "respiratory.persistent_cough"
[563] "respiratory.skipping_meals_because_you_felt_unwell"
[564] "respiratory.was_your_sense_of_smell_impaired"
[565] "respiratory.was_your_sense_of_taste_impaired"
[566] "respiratory.feeling_tiredfatigued"
[567] "respiratory.throat_swab_coronavirus_nose"
[568] "respiratory.throat_swab_test_nose"
[569] "respiratory.coronavirus_antibody_test"
[570] "respiratory.results_antibody_test"
[571] "respiratory.breath_diarrhoea_fatigue_fever_numeric"
[572] "respiratory.worst_ill_feel_numeric"
[573] "respiratory.persistent_cough_numeric"
[574] "respiratory.skipping_meals_because_you_felt_unwell_numeric"
[575] "respiratory.was_your_sense_of_smell_impaired_numeric"
[576] "respiratory.was_your_sense_of_taste_impaired_numeric"
[577] "respiratory.feeling_tiredfatigued_numeric"
[578] "respiratory.throat_swab_coronavirus_nose_numeric"
[579] "respiratory.throat_swab_test_nose_numeric"
[580] "respiratory.coronavirus_antibody_test_numeric"
[581] "respiratory.results_antibody_test_numeric"
[582] "respiratory.anosmia_binary"
[583] "respiratory.pcough_binary"
[584] "respiratory.fatigue_binary"
[585] "respiratory.skipped_meals_binary"
[586] "Sex_respiratory"
[587] "Age_respiratory"
[588] "covid_symptoms"
[589] "covid_probability"
[590] "covid_odds_ratio"
[591] "covid_odds_ratio_50_numeric"
[592] "covid_odds_ratio_50"
[593] "covid_probable_case_incl_screening_numeric"
[594] "covid_probable_case_incl_screening"
[595] "COPING_ID"
[596] "Birthyear_unc"
[597] "Birthmonth"
[598] "Birthday"
[599] "Birthyear_unc_numeric"
[600] "Birthmonth_numeric"
[601] "Birthday_numeric"
[602] "Birthyear_numeric"
[603] "Birthdate"
[604] "Cohort"
[605] "Ethnicity.unc"
[606] "Cohort_numeric"
[607] "Ethnicity.unc_numeric"
[608] "Ethnicity_full"
[609] "Transgender_uncleaned"
[610] "Transgender_uncleaned_numeric"
[611] "employment.what_is_your_highest_level_of_education"
[612] "employment.what_is_your_highest_level_of_education_numeric"
[613] "respiratory.coronavirus_week_antibody_test"
[614] "respiratory.coronavirus_week_antibody_test_numeric"
[615] "covid_test_positive_double_numeric"
[616] "covid_test_positive_double"
[617] "gad.covid_test_positive_numeric"
[618] "covid_test_positive"
[619] "age_category_collapsed_numeric"
[620] "age_category_collapsed"
[621] "age_category_collapsed_reordered"
[622] "Gender_collapsed_numeric"
[623] "Gender_collapsed"
[624] "Ethnicity_collapsed_numeric"
[625] "Ethnicity_collapsed"
[626] "Disorder_hierarchical_psychosis_numeric"
[627] "Disorder_hierarchical_psychosis"
[628] "Disorder_hierarchical_numeric"
[629] "Disorder_hierarchical"
[630] "gad.change_binary_numeric"
[631] "gad.change_binary"
[632] "phq.change_binary_numeric"
[633] "phq.change_binary"
[634] "ocir.change_binary_numeric"
[635] "ocir.change_binary"
[636] "prepandemic_3_months_numeric"
[637] "prepandemic_3_months"
[638] "prepandemic_6_months_numeric"
[639] "prepandemic_6_months"
[640] "prepandemic_9_months_numeric"
[641] "prepandemic_9_months"
Important vectors with collections of columns
Vectors for sum_score
[1] "gad.sum_score_prepan" "pcl.sum_score_prepan"
[3] "phq.sum_score_prepan" "phq.sum_score_8items_prepan"
[5] "ocir.sum_score_prepan" "gad.sum_score_base"
[7] "gad.sum_score_retro" "pcl.sum_score_base"
[9] "pcl.sum_score_retro" "phq.sum_score_base"
[11] "phq.sum_score_8items_base" "phq.sum_score_retro"
[13] "phq.sum_score_8items_retro" "ocir.sum_score_base"
[15] "ocir.sum_score_retro"
[1] "phq.sum_score_prepan" "phq.sum_score_base" "phq.sum_score_retro"
[1] "gad.sum_score_prepan" "gad.sum_score_base" "gad.sum_score_retro"
[1] "ocir.sum_score_prepan" "ocir.sum_score_base" "ocir.sum_score_retro"
[1] "pcl.sum_score_prepan" "pcl.sum_score_base" "pcl.sum_score_retro"
Vectors for diff_score
[1] "phq.diff_score_retro_prepan" "phq.diff_score_base_prepan"
[3] "phq.diff_score_base_retro" "gad.diff_score_retro_prepan"
[5] "gad.diff_score_base_prepan" "gad.diff_score_base_retro"
[7] "pcl.diff_score_base_prepan" "ocir.diff_score_retro_prepan"
[9] "ocir.diff_score_base_prepan" "ocir.diff_score_base_retro"
[1] "phq.diff_score_retro_prepan" "phq.diff_score_base_prepan"
[3] "phq.diff_score_base_retro"
[1] "gad.diff_score_retro_prepan" "gad.diff_score_base_prepan"
[3] "gad.diff_score_base_retro"
[1] "ocir.diff_score_retro_prepan" "ocir.diff_score_base_prepan"
[3] "ocir.diff_score_base_retro"
#ANALYSIS PLAN 1. Calculate mean change per disorder group i. Disorders (9) a. Rank the disorders by the size of the change ii. Sex iii. Age (13; RAMP; potentially collapse above 65 depending on group sizes) iv. Ethnicity groups (5; White European, Black (British), Asian, Arab, Mixed)
1. Questionnaire comparions: Calculate mean change per group
gad
Summary scores
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting gad sum score summary table
| No change |
Base |
0 |
21 |
2.665863 |
0.0 |
4.451322 |
2.1775181 |
4.4518534 |
| No change |
Prepan |
0 |
21 |
8.254932 |
7.0 |
6.202852 |
0.4754996 |
-0.9032129 |
| No change |
Retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| Worsening |
Base |
0 |
21 |
8.695957 |
7.0 |
5.696058 |
0.5245479 |
-0.8011604 |
| Worsening |
Prepan |
0 |
21 |
9.403875 |
8.0 |
5.859497 |
0.3389671 |
-0.9329372 |
| Worsening |
Retro |
0 |
21 |
4.638103 |
4.0 |
4.279377 |
1.3752419 |
1.9313176 |
| Improvement |
Base |
0 |
21 |
4.771279 |
3.0 |
4.830869 |
1.3672217 |
1.5731623 |
| Improvement |
Prepan |
0 |
21 |
9.228041 |
8.0 |
5.817921 |
0.3295928 |
-0.9032305 |
| Improvement |
Retro |
0 |
21 |
8.362857 |
7.0 |
5.468934 |
0.5124932 |
-0.5869968 |
| NA |
Base |
0 |
21 |
5.700000 |
4.5 |
5.994045 |
1.0357477 |
0.1012029 |
| NA |
Prepan |
0 |
21 |
10.000000 |
13.0 |
8.563488 |
-0.0313927 |
-1.9895986 |
| NA |
Retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
Differences scores
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting gad diff summary table
| No change |
Base - prepan |
-21 |
20 |
-2.0498783 |
-1 |
4.730325 |
-0.4870231 |
1.5079948 |
| No change |
Base - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| No change |
Prepan - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| Worsening |
Base - prepan |
-18 |
21 |
0.9694803 |
1 |
5.309832 |
-0.0145504 |
0.6007935 |
| Worsening |
Base - retro |
-21 |
21 |
4.0587466 |
3 |
4.286868 |
0.7700269 |
0.8792915 |
| Worsening |
Prepan - retro |
-21 |
18 |
-3.5772884 |
-3 |
5.108094 |
-0.2892807 |
0.4412892 |
| Improvement |
Base - prepan |
-21 |
12 |
-4.0760778 |
-3 |
5.490428 |
-0.2970813 |
0.1264514 |
| Improvement |
Base - retro |
-21 |
21 |
-3.5866667 |
-3 |
5.322797 |
0.4752668 |
2.1484694 |
| Improvement |
Prepan - retro |
-21 |
20 |
0.3536379 |
1 |
5.692678 |
-0.1576467 |
0.8754152 |
| NA |
Base - prepan |
-9 |
6 |
-1.5000000 |
-2 |
5.431390 |
0.0468089 |
-1.6798094 |
| NA |
Base - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| NA |
Prepan - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
Plots diff
makes this into percentages
Warning: Removed 56536 rows containing non-finite values (stat_count).

Warning: Removed 33099 rows containing non-finite values (stat_bin).

Warning: Removed 33099 rows containing non-finite values (stat_bin).

Warning: Removed 23437 rows containing non-finite values (stat_bin).

Plots sum
Warning: Removed 33099 rows containing non-finite values (stat_bin).

Warning: Removed 33099 rows containing non-finite values (stat_bin).

Violin plots
Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 33099 rows containing non-finite values (stat_ydensity).
Warning: Removed 33099 rows containing non-finite values (stat_summary).
Warning: Removed 33099 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 33099 rows containing non-finite values (stat_ydensity).
Warning: Removed 33099 rows containing non-finite values (stat_summary).
Warning: Removed 33099 rows containing missing values (geom_point).

Warning: `fun.y` is deprecated. Use `fun` instead.
Warning: `fun.ymin` is deprecated. Use `fun.min` instead.
Warning: `fun.ymax` is deprecated. Use `fun.max` instead.
Warning: Removed 33099 rows containing non-finite values (stat_ydensity).
Warning: Removed 33099 rows containing non-finite values (stat_summary).
Warning: Removed 33099 rows containing missing values (geom_point).

phq
Summary scores
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting phq sum score summary table
| No change |
Base |
0 |
27 |
3.779763 |
2 |
5.481075 |
2.0240159 |
3.8206843 |
| No change |
Prepan |
0 |
27 |
10.489318 |
9 |
7.211689 |
0.4737527 |
-0.7484781 |
| No change |
Retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| Worsening |
Base |
0 |
27 |
10.318865 |
9 |
6.601230 |
0.5934998 |
-0.5407978 |
| Worsening |
Prepan |
0 |
27 |
11.731892 |
11 |
6.742218 |
0.3025175 |
-0.7730617 |
| Worsening |
Retro |
0 |
27 |
5.713298 |
4 |
5.275219 |
1.4212461 |
1.9501353 |
| Improvement |
Base |
0 |
27 |
6.759112 |
5 |
5.758644 |
1.0575115 |
0.7067317 |
| Improvement |
Prepan |
0 |
27 |
11.511645 |
11 |
6.718528 |
0.3046296 |
-0.8118759 |
| Improvement |
Retro |
0 |
27 |
9.813261 |
9 |
6.780903 |
0.5958911 |
-0.4615114 |
| NA |
Base |
0 |
27 |
5.884892 |
3 |
6.885270 |
1.1461385 |
0.3684788 |
| NA |
Prepan |
0 |
25 |
11.424242 |
9 |
7.583000 |
0.3851207 |
-1.1446285 |
| NA |
Retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
Differences score
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
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Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
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Table for knitting phq diff summary table
| No change |
Base - prepan |
-25 |
23 |
-1.9826472 |
-1 |
5.133551 |
-0.3168253 |
1.6880781 |
| No change |
Base - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| No change |
Prepan - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| Worsening |
Base - prepan |
-23 |
24 |
0.7995943 |
1 |
5.546920 |
-0.0685706 |
0.8779614 |
| Worsening |
Base - retro |
-18 |
27 |
4.6013154 |
4 |
4.537987 |
0.9270470 |
1.3367436 |
| Worsening |
Prepan - retro |
-27 |
21 |
-4.2498646 |
-4 |
5.496923 |
-0.3766182 |
0.6037092 |
| Improvement |
Base - prepan |
-22 |
14 |
-4.0313183 |
-3 |
5.595035 |
-0.4118415 |
0.2308405 |
| Improvement |
Base - retro |
-24 |
23 |
-3.0461797 |
-3 |
5.576957 |
0.0339898 |
1.8480119 |
| Improvement |
Prepan - retro |
-27 |
22 |
-0.1211679 |
0 |
6.134474 |
-0.0254236 |
0.7299648 |
| NA |
Base - prepan |
-21 |
8 |
-0.5312500 |
0 |
6.111778 |
-1.1041870 |
1.8755762 |
| NA |
Base - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
| NA |
Prepan - retro |
Inf |
-Inf |
NaN |
NA |
NA |
NA |
NA |
Plots
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Violin plots
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ocir
Summary scores
Warning in min(., na.rm = T): no non-missing arguments to min; returning Inf
Warning in max(., na.rm = T): no non-missing arguments to max; returning -Inf
Table for knitting ocir sum score summary table
| Base |
0 |
72 |
17.80762 |
15 |
12.88086 |
1.1272426 |
1.1744348 |
| Prepan |
1 |
71 |
27.48730 |
26 |
14.13691 |
0.6265723 |
-0.0286904 |
| Retro |
0 |
71 |
16.99466 |
14 |
12.83344 |
1.0979581 |
0.9647110 |
Differences scores
Table for knitting ocir diff summary table
| Base - prepan |
-40 |
34 |
-8.0439560 |
-7 |
10.749154 |
-0.1101172 |
0.6746143 |
| Base - retro |
-44 |
72 |
0.9100517 |
0 |
9.658776 |
0.2846682 |
2.4704171 |
| Prepan - retro |
-30 |
27 |
-3.5058005 |
-3 |
9.301472 |
-0.0619316 |
0.3779813 |
Plots
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++CH: Rank the disorders by the size of the change
PCL: Calculate the total GLAD, COPING, RAMP baseline ## PCL
Table for knitting pcl sum score summary table
| Base - prepan |
-23 |
24 |
0.2068164 |
0 |
5.666463 |
-0.0743275 |
0.6542706 |
Table for knitting pcl diff summary table
| Base |
6 |
30 |
12.33784 |
11 |
6.051631 |
0.9357645 |
-0.0152704 |
| Prepan |
6 |
30 |
15.63577 |
15 |
6.120978 |
0.3799305 |
-0.7386952 |
For each item present percentages of how say that this is due to the pandemic
| pcl.cut_people_feeling_distant_retro_numeric |
0 |
5970 |
18.7 |
5970 (18.7%) |
| pcl.cut_people_feeling_distant_retro_numeric |
1 |
15402 |
48.3 |
15402 (48.3%) |
| pcl.cut_people_feeling_distant_retro_numeric |
Missing |
10512 |
33.0 |
10512 (33%) |
| pcl.difficulty_concentrating_retro_numeric |
0 |
9916 |
31.1 |
9916 (31.1%) |
| pcl.difficulty_concentrating_retro_numeric |
1 |
10289 |
32.3 |
10289 (32.3%) |
| pcl.difficulty_concentrating_retro_numeric |
Missing |
11679 |
36.6 |
11679 (36.6%) |
| pcl.feeling_irritable_or_having_angry_outbursts_retro_numeric |
0 |
8756 |
27.5 |
8756 (27.5%) |
| pcl.feeling_irritable_or_having_angry_outbursts_retro_numeric |
1 |
9870 |
31.0 |
9870 (31%) |
| pcl.feeling_irritable_or_having_angry_outbursts_retro_numeric |
Missing |
13258 |
41.6 |
13258 (41.6%) |
| pcl.stressful_experience_repeated_images_retro_numeric |
0 |
13112 |
41.1 |
13112 (41.1%) |
| pcl.stressful_experience_repeated_images_retro_numeric |
1 |
2902 |
9.1 |
2902 (9.1%) |
| pcl.stressful_experience_repeated_images_retro_numeric |
Missing |
15870 |
49.8 |
15870 (49.8%) |
| pcl.stressful_experience_upset_reminded_retro_numeric |
0 |
13848 |
43.4 |
13848 (43.4%) |
| pcl.stressful_experience_upset_reminded_retro_numeric |
1 |
3742 |
11.7 |
3742 (11.7%) |
| pcl.stressful_experience_upset_reminded_retro_numeric |
Missing |
14294 |
44.8 |
14294 (44.8%) |
| pcl.stressful_situation_avoiding_activities_retro_numeric |
0 |
9158 |
28.7 |
9158 (28.7%) |
| pcl.stressful_situation_avoiding_activities_retro_numeric |
1 |
2465 |
7.7 |
2465 (7.7%) |
| pcl.stressful_situation_avoiding_activities_retro_numeric |
Missing |
20261 |
63.5 |
20261 (63.5%) |
Plots sum
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Create subsets of data for analyses
Filter data frame to create 2 additional datasets. Additional exclusion criteria (beyond those listed above) are specified below:
- Retrospective - baseline change anlyses
- Exclude individuals missing retrospective and/or baseline data
- Prepandemic - baseline change analyses i. Exclude individuals missing pandemic and/or baseline data ii. Exclude individuals with prepandemic data collected after 1st March.
Retro-baseline analyses
[1] 23539 641
Prepan-baseline analyses Exclude individuals with NA for MHD, age, gender; exclude if prepan data collected after 1 March
[1] 11230 641
Prepan-baseline analyses Exclude individuals with NA for MHD, age, gender; exclude if prepan data collected after 1 March (to ensure comparability with prepan analyses)
[1] 9745 641
age^2 sensitivity Exclude individuals with NA for continuous Age variable
[1] 24816 641
[1] 17092 641
[1] 11230 641
Sensitivity analysis for individuals who signed up to GLAD (prepan) either 3, 6 or 9 months before the pendemic began.
Regression models (Regress covariates out of the change? Which?)
- Model 0: Disorders
- Model 1: Model 0 + Sex + Age + Ethnicity + Time registration and baseline
Re-calculate change
Re-rank the change again
PCL:
- Calculate the total GLAD, COPING, RAMP baseline
- For each item:
- present percentages of how say that this is due to the pandemic
- Calculate a variable PCL pandemic score
- If one item is highly endorsed due to pandemic -> exclude in sensitivity analysis
2. Regression
Regress covariates out of the change? Which?
Model naming conventions: 0 - unadjusted 1 - adjusted 2 - adjusted with age^2 a - hierarchical disorders b - overlapping disorder categories
++MD: We may want to exclude disorders from Model b that aren’t including in the hierarchy (e.g. ADHD, ASD)
Functions
GAD baseline, not controlling for prior symptoms
Model 0a: Disorder_hierarchical, Unadjusted
#SB Hashing out this chunk of code as it is not included in our final analysis and is currently breaking the code.
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.67 |
2.59 |
2.76 |
0.04 |
0.00e+00 |
| Depressive and anxiety disorder |
5.63 |
5.50 |
5.77 |
0.07 |
0.00e+00 |
| Only depressive disorder |
2.08 |
1.90 |
2.25 |
0.09 |
4.32e-117 |
| Only anxiety disorder |
4.03 |
3.81 |
4.26 |
0.11 |
1.97e-264 |
| Eating disorders |
1.46 |
1.22 |
1.69 |
0.12 |
1.10e-33 |
| OCDs |
1.94 |
1.71 |
2.17 |
0.12 |
8.53e-63 |
| Psychotic and bipolar disorder |
0.38 |
-0.26 |
1.02 |
0.33 |
0.24 |
| Only psychotic disorder |
0.35 |
-0.20 |
0.90 |
0.28 |
0.21 |
| Only bipolar disorder |
0.46 |
0.11 |
0.80 |
0.18 |
0.009 |
| PTSD |
1.56 |
1.35 |
1.77 |
0.11 |
2.35e-48 |
| ASD |
2.18 |
1.77 |
2.59 |
0.21 |
1.80e-25 |
| ADHD |
1.17 |
0.63 |
1.71 |
0.28 |
2.36e-05 |
| Personality disorder |
2.19 |
1.89 |
2.49 |
0.15 |
5.79e-46 |
| 31331 |
0.22 |
0.22 |
1503.62 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.67 |
5.38 |
5.96 |
0.15 |
9.14e-313 |
| Anxiety disorders |
2.96 |
2.70 |
3.22 |
0.13 |
1.10e-109 |
| Eating disorders |
2.10 |
1.30 |
2.91 |
0.41 |
3.42e-07 |
| OCDs |
4.01 |
3.35 |
4.67 |
0.34 |
1.26e-32 |
| PTSD |
3.96 |
3.30 |
4.63 |
0.34 |
2.24e-31 |
| Depressive disorders |
4.53 |
4.39 |
4.66 |
0.07 |
0.00e+00 |
| Bipolar disorders |
6.08 |
5.76 |
6.39 |
0.16 |
1.26e-299 |
| Female |
1.00 |
0.86 |
1.14 |
0.07 |
3.17e-44 |
| Non-binary/Self-defined |
1.60 |
1.04 |
2.16 |
0.29 |
2.64e-08 |
| age_category_collapsed_reordered16-18 |
3.23 |
2.85 |
3.60 |
0.19 |
1.44e-63 |
| 19-25 years |
1.74 |
1.48 |
2.00 |
0.13 |
9.41e-40 |
| 36-45 years |
-0.84 |
-1.05 |
-0.62 |
0.11 |
2.78e-14 |
| 46-55 years |
-1.57 |
-1.77 |
-1.37 |
0.10 |
1.41e-53 |
| 56-65 years |
-2.60 |
-2.80 |
-2.40 |
0.10 |
4.06e-145 |
| 66-70 years |
-3.58 |
-3.83 |
-3.33 |
0.13 |
5.63e-169 |
| 71-75 years |
-3.78 |
-4.07 |
-3.49 |
0.15 |
6.57e-143 |
| 76+ years |
-3.69 |
-4.13 |
-3.25 |
0.22 |
2.30e-60 |
| Mixed or multiple ethnic origins |
0.04 |
-0.41 |
0.49 |
0.23 |
0.85 |
| Asian or Asian British |
-0.31 |
-0.86 |
0.23 |
0.28 |
0.26 |
| African or African British |
-0.25 |
-1.18 |
0.68 |
0.47 |
0.59 |
| Other ethnicity |
0.97 |
0.15 |
1.80 |
0.42 |
0.02 |
| Time difference: Lockdown to baseline |
-0.24 |
-0.27 |
-0.21 |
0.02 |
1.66e-55 |
| 31331 |
0.22 |
0.22 |
1503.62 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.57 |
5.28 |
5.85 |
0.14 |
2.40e-317 |
| Depressive and anxiety disorder |
4.60 |
4.46 |
4.75 |
0.07 |
0.00e+00 |
| Only depressive disorder |
1.81 |
1.63 |
1.99 |
0.09 |
2.60e-83 |
| Only anxiety disorder |
3.05 |
2.82 |
3.28 |
0.12 |
6.22e-145 |
| Eating disorders |
0.90 |
0.67 |
1.13 |
0.12 |
3.61e-14 |
| OCDs |
1.45 |
1.23 |
1.67 |
0.11 |
5.23e-37 |
| Psychotic and bipolar disorder |
0.74 |
0.11 |
1.37 |
0.32 |
0.02 |
| Only psychotic disorder |
0.51 |
-0.03 |
1.05 |
0.27 |
0.06 |
| Only bipolar disorder |
0.65 |
0.31 |
0.99 |
0.17 |
1.79e-04 |
| PTSD |
1.58 |
1.38 |
1.79 |
0.11 |
1.05e-50 |
| ASD |
1.31 |
0.90 |
1.71 |
0.21 |
2.89e-10 |
| ADHD |
0.46 |
-0.08 |
0.99 |
0.27 |
0.09 |
| Personality disorder |
1.82 |
1.52 |
2.11 |
0.15 |
2.55e-33 |
| Female |
0.94 |
0.81 |
1.08 |
0.07 |
1.36e-42 |
| Non-binary/Self-defined |
0.69 |
0.15 |
1.23 |
0.28 |
0.01 |
| age_category_collapsed_reordered16-18 |
3.33 |
2.98 |
3.68 |
0.18 |
7.57e-76 |
| 19-25 years |
1.61 |
1.36 |
1.86 |
0.13 |
2.50e-37 |
| 36-45 years |
-0.64 |
-0.85 |
-0.44 |
0.11 |
1.15e-09 |
| 46-55 years |
-1.15 |
-1.35 |
-0.96 |
0.10 |
8.01e-32 |
| 56-65 years |
-2.02 |
-2.21 |
-1.83 |
0.10 |
7.82e-93 |
| 66-70 years |
-2.98 |
-3.23 |
-2.73 |
0.13 |
1.70e-120 |
| 71-75 years |
-3.19 |
-3.47 |
-2.90 |
0.15 |
6.34e-106 |
| 76+ years |
-3.08 |
-3.50 |
-2.65 |
0.22 |
1.24e-45 |
| Mixed or multiple ethnic origins |
0.10 |
-0.33 |
0.53 |
0.22 |
0.66 |
| Asian or Asian British |
0.16 |
-0.36 |
0.67 |
0.26 |
0.55 |
| African or African British |
-0.17 |
-1.05 |
0.71 |
0.45 |
0.71 |
| Other ethnicity |
0.74 |
-0.05 |
1.52 |
0.40 |
0.06 |
| Key worker |
-0.35 |
-0.47 |
-0.22 |
0.06 |
4.42e-08 |
| Time difference: Lockdown to baseline |
-0.25 |
-0.27 |
-0.22 |
0.01 |
1.60e-65 |
| 31331 |
0.22 |
0.22 |
1503.62 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with Age^2
| Intercept |
1.78 |
1.48 |
2.09 |
0.16 |
4.29e-30 |
| Anxiety disorders |
2.79 |
2.49 |
3.10 |
0.15 |
3.88e-72 |
| Eating disorders |
2.27 |
1.33 |
3.20 |
0.48 |
2.04e-06 |
| OCDs |
4.46 |
3.65 |
5.26 |
0.41 |
3.29e-27 |
| PTSD |
4.24 |
3.37 |
5.12 |
0.45 |
2.15e-21 |
| Depressive disorders |
4.80 |
4.64 |
4.95 |
0.08 |
0.00e+00 |
| Bipolar disorders |
6.26 |
5.92 |
6.60 |
0.17 |
6.20e-274 |
| Female |
0.71 |
0.56 |
0.86 |
0.08 |
2.18e-20 |
| Non-binary/Self-defined |
1.44 |
0.84 |
2.05 |
0.31 |
2.84e-06 |
| Age |
-248.64 |
-259.74 |
-237.54 |
5.66 |
0.00e+00 |
| Age^2 |
29.43 |
19.41 |
39.45 |
5.11 |
8.72e-09 |
| Mixed or multiple ethnic origins |
0.03 |
-0.46 |
0.53 |
0.25 |
0.90 |
| Asian or Asian British |
-0.06 |
-0.71 |
0.60 |
0.33 |
0.87 |
| African or African British |
0.02 |
-1.01 |
1.06 |
0.53 |
0.96 |
| Other ethnicity |
1.44 |
0.51 |
2.38 |
0.48 |
0.002 |
| Time difference: Lockdown to baseline |
0.04 |
0.00 |
0.08 |
0.02 |
0.03 |
| 24462 |
0.27 |
0.27 |
1541.15 |
0.00e+00 |
6 |
Model 2b: Disorder hierarchical, Adjusted with Age^2
| Intercept |
1.86 |
1.56 |
2.15 |
0.15 |
1.11e-34 |
| Depressive and anxiety disorder |
4.91 |
4.75 |
5.07 |
0.08 |
0.00e+00 |
| Only depressive disorder |
1.98 |
1.78 |
2.19 |
0.10 |
8.03e-79 |
| Only anxiety disorder |
3.02 |
2.75 |
3.29 |
0.14 |
1.46e-104 |
| Eating disorders |
1.09 |
0.84 |
1.34 |
0.13 |
2.20e-17 |
| OCDs |
1.38 |
1.13 |
1.62 |
0.12 |
8.44e-29 |
| Psychotic and bipolar disorder |
0.44 |
-0.27 |
1.15 |
0.36 |
0.23 |
| Only psychotic disorder |
0.48 |
-0.10 |
1.06 |
0.30 |
0.10 |
| Only bipolar disorder |
0.64 |
0.29 |
0.99 |
0.18 |
3.50e-04 |
| PTSD |
1.69 |
1.47 |
1.92 |
0.11 |
3.91e-49 |
| ASD |
1.25 |
0.78 |
1.71 |
0.24 |
1.44e-07 |
| ADHD |
0.25 |
-0.37 |
0.87 |
0.32 |
0.43 |
| Personality disorder |
1.75 |
1.43 |
2.06 |
0.16 |
4.68e-27 |
| Female |
0.60 |
0.45 |
0.74 |
0.07 |
3.60e-16 |
| Non-binary/Self-defined |
0.55 |
-0.03 |
1.12 |
0.30 |
0.07 |
| Age |
-209.28 |
-220.39 |
-198.16 |
5.67 |
3.08e-289 |
| Age^2 |
19.55 |
9.65 |
29.45 |
5.05 |
1.09e-04 |
| Mixed or multiple ethnic origins |
0.00 |
-0.47 |
0.48 |
0.24 |
0.99 |
| Asian or Asian British |
0.34 |
-0.28 |
0.95 |
0.31 |
0.28 |
| African or African British |
0.03 |
-0.95 |
1.01 |
0.50 |
0.96 |
| Other ethnicity |
1.05 |
0.16 |
1.93 |
0.45 |
0.02 |
| Key worker |
-0.35 |
-0.48 |
-0.22 |
0.07 |
2.70e-07 |
| Time difference: Lockdown to baseline |
0.05 |
0.02 |
0.09 |
0.02 |
0.004 |
| 24462 |
0.27 |
0.27 |
1541.15 |
0.00e+00 |
6 |
GAD prepan
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
-1.16 |
-2.09 |
-0.22 |
0.48 |
0.02 |
| Anxiety disorders |
0.19 |
-0.84 |
1.22 |
0.53 |
0.72 |
| Eating disorders |
-0.57 |
-2.60 |
1.47 |
1.04 |
0.59 |
| OCDs |
-0.14 |
-1.55 |
1.26 |
0.72 |
0.84 |
| PTSD |
-0.06 |
-1.68 |
1.57 |
0.83 |
0.95 |
| Depressive disorders |
0.85 |
-0.09 |
1.79 |
0.48 |
0.08 |
| Bipolar disorders |
0.80 |
-0.21 |
1.81 |
0.52 |
0.12 |
| 11144 |
0.00 |
0.00 |
2.98 |
0.007 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
-0.83 |
-1.51 |
-0.16 |
0.34 |
0.02 |
| Depressive and anxiety disorder |
0.45 |
-0.24 |
1.13 |
0.35 |
0.20 |
| Only depressive disorder |
0.98 |
0.24 |
1.72 |
0.38 |
0.009 |
| Only anxiety disorder |
-0.24 |
-1.01 |
0.53 |
0.40 |
0.54 |
| Eating disorders |
0.18 |
-0.15 |
0.51 |
0.17 |
0.29 |
| OCDs |
-0.26 |
-0.57 |
0.05 |
0.16 |
0.11 |
| Psychotic and bipolar disorder |
-0.51 |
-1.42 |
0.39 |
0.46 |
0.27 |
| Only psychotic disorder |
0.76 |
0.00 |
1.52 |
0.39 |
0.05 |
| Only bipolar disorder |
0.20 |
-0.26 |
0.65 |
0.23 |
0.40 |
| PTSD |
0.14 |
-0.16 |
0.43 |
0.15 |
0.36 |
| ASD |
0.16 |
-0.44 |
0.76 |
0.31 |
0.61 |
| ADHD |
-0.74 |
-1.56 |
0.09 |
0.42 |
0.08 |
| Personality disorder |
-0.16 |
-0.57 |
0.24 |
0.21 |
0.43 |
| 11144 |
0.00 |
0.00 |
2.98 |
0.007 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.46 |
-2.56 |
-0.37 |
0.56 |
0.009 |
| Anxiety disorders |
0.13 |
-0.91 |
1.16 |
0.53 |
0.81 |
| Eating disorders |
-0.72 |
-2.75 |
1.32 |
1.04 |
0.49 |
| OCDs |
-0.24 |
-1.65 |
1.16 |
0.72 |
0.74 |
| PTSD |
-0.21 |
-1.85 |
1.43 |
0.84 |
0.80 |
| Depressive disorders |
0.75 |
-0.19 |
1.69 |
0.48 |
0.12 |
| Bipolar disorders |
0.76 |
-0.26 |
1.77 |
0.52 |
0.14 |
| Female |
0.49 |
0.21 |
0.77 |
0.14 |
5.29e-04 |
| Non-binary/Self-defined |
0.42 |
-0.37 |
1.22 |
0.40 |
0.29 |
| age_category_collapsed_reordered16-18 |
-0.50 |
-1.16 |
0.17 |
0.34 |
0.14 |
| 19-25 years |
0.04 |
-0.32 |
0.40 |
0.18 |
0.84 |
| 36-45 years |
0.16 |
-0.16 |
0.48 |
0.16 |
0.33 |
| 46-55 years |
-0.03 |
-0.34 |
0.28 |
0.16 |
0.86 |
| 56-65 years |
0.16 |
-0.19 |
0.50 |
0.18 |
0.37 |
| 66-70 years |
-0.24 |
-0.85 |
0.36 |
0.31 |
0.43 |
| 71-75 years |
-0.31 |
-1.12 |
0.49 |
0.41 |
0.44 |
| 76+ years |
0.43 |
-1.13 |
1.99 |
0.80 |
0.59 |
| Mixed or multiple ethnic origins |
0.30 |
-0.42 |
1.01 |
0.37 |
0.42 |
| Asian or Asian British |
-0.25 |
-1.41 |
0.92 |
0.60 |
0.68 |
| African or African British |
-1.25 |
-3.01 |
0.51 |
0.90 |
0.16 |
| Other ethnicity |
0.04 |
-1.08 |
1.17 |
0.57 |
0.94 |
| Time difference: Lockdown to baseline |
0.00 |
-0.07 |
0.06 |
0.03 |
0.89 |
| 11144 |
0.00 |
0.00 |
2.98 |
0.007 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.18 |
-2.07 |
-0.29 |
0.46 |
0.010 |
| Depressive and anxiety disorder |
0.38 |
-0.31 |
1.08 |
0.35 |
0.27 |
| Only depressive disorder |
0.92 |
0.18 |
1.67 |
0.38 |
0.02 |
| Only anxiety disorder |
-0.29 |
-1.07 |
0.49 |
0.40 |
0.47 |
| Eating disorders |
0.14 |
-0.20 |
0.47 |
0.17 |
0.42 |
| OCDs |
-0.26 |
-0.58 |
0.05 |
0.16 |
0.10 |
| Psychotic and bipolar disorder |
-0.40 |
-1.31 |
0.52 |
0.47 |
0.39 |
| Only psychotic disorder |
0.79 |
0.02 |
1.55 |
0.39 |
0.04 |
| Only bipolar disorder |
0.29 |
-0.17 |
0.74 |
0.23 |
0.22 |
| PTSD |
0.11 |
-0.18 |
0.41 |
0.15 |
0.46 |
| ASD |
0.25 |
-0.36 |
0.87 |
0.31 |
0.42 |
| ADHD |
-0.72 |
-1.55 |
0.11 |
0.42 |
0.09 |
| Personality disorder |
-0.19 |
-0.60 |
0.22 |
0.21 |
0.36 |
| Female |
0.46 |
0.18 |
0.74 |
0.14 |
0.001 |
| Non-binary/Self-defined |
0.46 |
-0.33 |
1.25 |
0.40 |
0.26 |
| age_category_collapsed_reordered16-18 |
-0.49 |
-1.15 |
0.17 |
0.34 |
0.15 |
| 19-25 years |
0.04 |
-0.32 |
0.41 |
0.18 |
0.81 |
| 36-45 years |
0.12 |
-0.20 |
0.43 |
0.16 |
0.47 |
| 46-55 years |
-0.09 |
-0.40 |
0.22 |
0.16 |
0.55 |
| 56-65 years |
0.09 |
-0.26 |
0.44 |
0.18 |
0.62 |
| 66-70 years |
-0.33 |
-0.94 |
0.28 |
0.31 |
0.29 |
| 71-75 years |
-0.30 |
-1.11 |
0.51 |
0.41 |
0.47 |
| 76+ years |
0.38 |
-1.19 |
1.94 |
0.80 |
0.64 |
| Mixed or multiple ethnic origins |
0.32 |
-0.40 |
1.04 |
0.37 |
0.39 |
| Asian or Asian British |
-0.18 |
-1.35 |
0.98 |
0.60 |
0.76 |
| African or African British |
-1.18 |
-2.94 |
0.58 |
0.90 |
0.19 |
| Other ethnicity |
-0.06 |
-1.17 |
1.04 |
0.56 |
0.91 |
| Key worker |
0.17 |
-0.05 |
0.39 |
0.11 |
0.12 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.07 |
0.06 |
0.03 |
0.85 |
| 11144 |
0.00 |
0.00 |
2.98 |
0.007 |
6 |
Model 2a: Disorder hierarchical, Adjusted with Age^2
Model 0a + Gender_collapsed + age^2+ Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.44 |
-2.51 |
-0.36 |
0.55 |
0.009 |
| Anxiety disorders |
0.13 |
-0.90 |
1.17 |
0.53 |
0.80 |
| Eating disorders |
-0.70 |
-2.74 |
1.33 |
1.04 |
0.50 |
| OCDs |
-0.23 |
-1.64 |
1.17 |
0.72 |
0.75 |
| PTSD |
-0.19 |
-1.83 |
1.45 |
0.84 |
0.82 |
| Depressive disorders |
0.76 |
-0.18 |
1.71 |
0.48 |
0.11 |
| Bipolar disorders |
0.76 |
-0.26 |
1.78 |
0.52 |
0.14 |
| Female |
0.49 |
0.21 |
0.77 |
0.14 |
5.24e-04 |
| Non-binary/Self-defined |
0.43 |
-0.37 |
1.22 |
0.40 |
0.29 |
| Age |
0.90 |
-10.29 |
12.09 |
5.71 |
0.87 |
| Age^2 |
-9.06 |
-20.02 |
1.89 |
5.59 |
0.10 |
| Mixed or multiple ethnic origins |
0.30 |
-0.42 |
1.02 |
0.37 |
0.42 |
| Asian or Asian British |
-0.25 |
-1.42 |
0.92 |
0.60 |
0.67 |
| African or African British |
-1.26 |
-3.02 |
0.50 |
0.90 |
0.16 |
| Other ethnicity |
0.04 |
-1.08 |
1.16 |
0.57 |
0.95 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.07 |
0.06 |
0.03 |
0.85 |
| 11144 |
0.00 |
0.00 |
2.98 |
0.007 |
6 |
Model 2b: Overlapping disorders, Adjusted with Age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.19 |
-2.06 |
-0.33 |
0.44 |
0.007 |
| Depressive and anxiety disorder |
0.41 |
-0.28 |
1.10 |
0.35 |
0.25 |
| Only depressive disorder |
0.95 |
0.21 |
1.70 |
0.38 |
0.01 |
| Only anxiety disorder |
-0.27 |
-1.05 |
0.51 |
0.40 |
0.50 |
| Eating disorders |
0.13 |
-0.20 |
0.47 |
0.17 |
0.44 |
| OCDs |
-0.26 |
-0.58 |
0.05 |
0.16 |
0.10 |
| Psychotic and bipolar disorder |
-0.41 |
-1.32 |
0.50 |
0.47 |
0.38 |
| Only psychotic disorder |
0.79 |
0.03 |
1.55 |
0.39 |
0.04 |
| Only bipolar disorder |
0.28 |
-0.17 |
0.74 |
0.23 |
0.23 |
| PTSD |
0.10 |
-0.19 |
0.40 |
0.15 |
0.50 |
| ASD |
0.24 |
-0.37 |
0.85 |
0.31 |
0.44 |
| ADHD |
-0.72 |
-1.55 |
0.10 |
0.42 |
0.09 |
| Personality disorder |
-0.18 |
-0.59 |
0.23 |
0.21 |
0.39 |
| Female |
0.46 |
0.18 |
0.74 |
0.14 |
0.001 |
| Non-binary/Self-defined |
0.46 |
-0.33 |
1.25 |
0.40 |
0.25 |
| Age |
-2.04 |
-13.45 |
9.36 |
5.82 |
0.73 |
| Age^2 |
-8.20 |
-19.49 |
3.09 |
5.76 |
0.15 |
| Mixed or multiple ethnic origins |
0.32 |
-0.40 |
1.04 |
0.37 |
0.38 |
| Asian or Asian British |
-0.19 |
-1.36 |
0.98 |
0.60 |
0.75 |
| African or African British |
-1.19 |
-2.95 |
0.57 |
0.90 |
0.18 |
| Other ethnicity |
-0.06 |
-1.17 |
1.04 |
0.56 |
0.91 |
| Key worker |
0.16 |
-0.06 |
0.38 |
0.11 |
0.15 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.07 |
0.06 |
0.03 |
0.81 |
| 11144 |
0.00 |
0.00 |
2.98 |
0.007 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.25 |
1.42 |
3.07 |
0.42 |
9.22e-08 |
| gad.sum_score_prepan |
0.55 |
0.53 |
0.56 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.59 |
-0.31 |
1.49 |
0.46 |
0.20 |
| Eating disorders |
0.79 |
-0.98 |
2.57 |
0.91 |
0.38 |
| OCDs |
1.42 |
0.19 |
2.65 |
0.63 |
0.02 |
| PTSD |
1.15 |
-0.27 |
2.57 |
0.73 |
0.11 |
| Depressive disorders |
1.51 |
0.68 |
2.33 |
0.42 |
3.39e-04 |
| Bipolar disorders |
1.86 |
0.98 |
2.75 |
0.45 |
3.80e-05 |
| 11144 |
0.32 |
0.32 |
743.84 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.98 |
2.38 |
3.58 |
0.30 |
1.34e-22 |
| gad.sum_score_prepan |
0.52 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.83 |
0.23 |
1.42 |
0.30 |
0.006 |
| Only depressive disorder |
-0.24 |
-0.88 |
0.40 |
0.33 |
0.47 |
| Only anxiety disorder |
0.11 |
-0.56 |
0.78 |
0.34 |
0.76 |
| Eating disorders |
0.73 |
0.44 |
1.02 |
0.15 |
6.17e-07 |
| OCDs |
0.61 |
0.34 |
0.88 |
0.14 |
1.08e-05 |
| Psychotic and bipolar disorder |
-0.53 |
-1.31 |
0.26 |
0.40 |
0.19 |
| Only psychotic disorder |
0.39 |
-0.27 |
1.05 |
0.34 |
0.24 |
| Only bipolar disorder |
0.17 |
-0.23 |
0.56 |
0.20 |
0.41 |
| PTSD |
0.75 |
0.50 |
1.01 |
0.13 |
5.96e-09 |
| ASD |
0.90 |
0.38 |
1.42 |
0.27 |
7.08e-04 |
| ADHD |
-0.13 |
-0.84 |
0.59 |
0.36 |
0.73 |
| Personality disorder |
0.92 |
0.56 |
1.27 |
0.18 |
3.95e-07 |
| 11165 |
0.01 |
0.01 |
11.04 |
2.61e-12 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.44 |
1.48 |
3.41 |
0.49 |
7.57e-07 |
| gad.sum_score_prepan |
0.52 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.56 |
-0.34 |
1.46 |
0.46 |
0.22 |
| Eating disorders |
0.67 |
-1.09 |
2.44 |
0.90 |
0.45 |
| OCDs |
1.21 |
-0.01 |
2.43 |
0.62 |
0.05 |
| PTSD |
1.42 |
0.00 |
2.84 |
0.73 |
0.05 |
| Depressive disorders |
1.61 |
0.79 |
2.43 |
0.42 |
1.29e-04 |
| Bipolar disorders |
2.08 |
1.20 |
2.97 |
0.45 |
4.22e-06 |
| Female |
0.52 |
0.28 |
0.76 |
0.12 |
2.04e-05 |
| Non-binary/Self-defined |
0.81 |
0.13 |
1.50 |
0.35 |
0.02 |
| age_category_collapsed_reordered16-18 |
0.95 |
0.37 |
1.54 |
0.30 |
0.001 |
| 19-25 years |
0.73 |
0.41 |
1.04 |
0.16 |
5.96e-06 |
| 36-45 years |
-0.18 |
-0.45 |
0.10 |
0.14 |
0.20 |
| 46-55 years |
-0.51 |
-0.77 |
-0.24 |
0.14 |
2.06e-04 |
| 56-65 years |
-1.00 |
-1.30 |
-0.70 |
0.15 |
1.02e-10 |
| 66-70 years |
-2.05 |
-2.58 |
-1.52 |
0.27 |
5.10e-14 |
| 71-75 years |
-2.35 |
-3.06 |
-1.65 |
0.36 |
6.05e-11 |
| 76+ years |
-1.76 |
-3.12 |
-0.41 |
0.69 |
0.01 |
| Mixed or multiple ethnic origins |
0.08 |
-0.55 |
0.71 |
0.32 |
0.80 |
| Asian or Asian British |
-0.16 |
-1.18 |
0.85 |
0.52 |
0.75 |
| African or African British |
-0.47 |
-1.99 |
1.05 |
0.78 |
0.55 |
| Other ethnicity |
0.50 |
-0.48 |
1.47 |
0.50 |
0.32 |
| Key worker |
-0.33 |
-0.52 |
-0.15 |
0.10 |
5.01e-04 |
| Time difference: Lockdown to baseline |
0.00 |
-0.06 |
0.05 |
0.03 |
0.92 |
| 11165 |
0.01 |
0.01 |
11.04 |
2.61e-12 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.08 |
2.30 |
3.85 |
0.40 |
1.02e-14 |
| gad.sum_score_prepan |
0.49 |
0.48 |
0.51 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.92 |
0.33 |
1.52 |
0.30 |
0.002 |
| Only depressive disorder |
0.01 |
-0.63 |
0.66 |
0.33 |
0.96 |
| Only anxiety disorder |
0.07 |
-0.60 |
0.74 |
0.34 |
0.83 |
| Eating disorders |
0.61 |
0.32 |
0.89 |
0.15 |
3.79e-05 |
| OCDs |
0.53 |
0.26 |
0.80 |
0.14 |
1.22e-04 |
| Psychotic and bipolar disorder |
-0.26 |
-1.05 |
0.52 |
0.40 |
0.51 |
| Only psychotic disorder |
0.45 |
-0.20 |
1.10 |
0.33 |
0.18 |
| Only bipolar disorder |
0.32 |
-0.07 |
0.71 |
0.20 |
0.11 |
| PTSD |
0.82 |
0.56 |
1.07 |
0.13 |
2.73e-10 |
| ASD |
0.70 |
0.18 |
1.23 |
0.27 |
0.009 |
| ADHD |
-0.21 |
-0.92 |
0.50 |
0.36 |
0.55 |
| Personality disorder |
0.80 |
0.44 |
1.15 |
0.18 |
1.06e-05 |
| Female |
0.40 |
0.16 |
0.64 |
0.12 |
9.85e-04 |
| Non-binary/Self-defined |
0.41 |
-0.27 |
1.09 |
0.35 |
0.23 |
| age_category_collapsed_reordered16-18 |
1.04 |
0.47 |
1.61 |
0.29 |
3.54e-04 |
| 19-25 years |
0.75 |
0.44 |
1.06 |
0.16 |
2.43e-06 |
| 36-45 years |
-0.15 |
-0.42 |
0.12 |
0.14 |
0.29 |
| 46-55 years |
-0.43 |
-0.70 |
-0.17 |
0.14 |
0.001 |
| 56-65 years |
-0.87 |
-1.17 |
-0.56 |
0.15 |
1.85e-08 |
| 66-70 years |
-1.84 |
-2.37 |
-1.31 |
0.27 |
8.37e-12 |
| 71-75 years |
-2.03 |
-2.73 |
-1.34 |
0.36 |
1.04e-08 |
| 76+ years |
-1.53 |
-2.87 |
-0.18 |
0.69 |
0.03 |
| Mixed or multiple ethnic origins |
0.06 |
-0.56 |
0.68 |
0.32 |
0.86 |
| Asian or Asian British |
-0.03 |
-1.03 |
0.97 |
0.51 |
0.96 |
| African or African British |
-0.39 |
-1.90 |
1.12 |
0.77 |
0.62 |
| Other ethnicity |
0.40 |
-0.55 |
1.34 |
0.48 |
0.41 |
| Key worker |
-0.22 |
-0.41 |
-0.04 |
0.09 |
0.02 |
| Time difference: Lockdown to baseline |
0.00 |
-0.05 |
0.06 |
0.03 |
0.89 |
| 11165 |
0.01 |
0.01 |
11.04 |
2.61e-12 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.18 |
1.24 |
3.13 |
0.48 |
6.32e-06 |
| gad.sum_score_prepan |
0.52 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.54 |
-0.35 |
1.44 |
0.46 |
0.24 |
| Eating disorders |
0.65 |
-1.12 |
2.41 |
0.90 |
0.47 |
| OCDs |
1.22 |
0.00 |
2.44 |
0.62 |
0.05 |
| PTSD |
1.39 |
-0.03 |
2.81 |
0.72 |
0.05 |
| Depressive disorders |
1.58 |
0.76 |
2.40 |
0.42 |
1.69e-04 |
| Bipolar disorders |
2.05 |
1.16 |
2.94 |
0.45 |
5.84e-06 |
| Female |
0.50 |
0.26 |
0.74 |
0.12 |
3.76e-05 |
| Non-binary/Self-defined |
0.79 |
0.11 |
1.48 |
0.35 |
0.02 |
| Age |
-71.59 |
-81.58 |
-61.60 |
5.10 |
2.00e-44 |
| Age^2 |
-9.17 |
-18.94 |
0.60 |
4.98 |
0.07 |
| Mixed or multiple ethnic origins |
0.06 |
-0.56 |
0.69 |
0.32 |
0.85 |
| Asian or Asian British |
-0.16 |
-1.17 |
0.86 |
0.52 |
0.76 |
| African or African British |
-0.46 |
-1.98 |
1.06 |
0.78 |
0.55 |
| Other ethnicity |
0.49 |
-0.49 |
1.46 |
0.50 |
0.33 |
| Key worker |
-0.34 |
-0.53 |
-0.16 |
0.10 |
3.12e-04 |
| Time difference: Lockdown to baseline |
0.00 |
-0.06 |
0.05 |
0.03 |
0.95 |
| 11165 |
0.01 |
0.01 |
11.04 |
2.61e-12 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.88 |
2.13 |
3.63 |
0.38 |
5.85e-14 |
| gad.sum_score_prepan |
0.49 |
0.48 |
0.51 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.88 |
0.29 |
1.47 |
0.30 |
0.004 |
| Only depressive disorder |
0.00 |
-0.64 |
0.64 |
0.33 |
0.99 |
| Only anxiety disorder |
0.04 |
-0.63 |
0.71 |
0.34 |
0.90 |
| Eating disorders |
0.61 |
0.32 |
0.90 |
0.15 |
3.27e-05 |
| OCDs |
0.52 |
0.25 |
0.79 |
0.14 |
1.44e-04 |
| Psychotic and bipolar disorder |
-0.25 |
-1.03 |
0.54 |
0.40 |
0.54 |
| Only psychotic disorder |
0.47 |
-0.18 |
1.12 |
0.33 |
0.16 |
| Only bipolar disorder |
0.32 |
-0.07 |
0.71 |
0.20 |
0.11 |
| PTSD |
0.83 |
0.57 |
1.08 |
0.13 |
1.83e-10 |
| ASD |
0.73 |
0.20 |
1.25 |
0.27 |
0.007 |
| ADHD |
-0.25 |
-0.96 |
0.46 |
0.36 |
0.49 |
| Personality disorder |
0.75 |
0.40 |
1.10 |
0.18 |
3.10e-05 |
| Female |
0.39 |
0.15 |
0.63 |
0.12 |
0.002 |
| Non-binary/Self-defined |
0.40 |
-0.28 |
1.08 |
0.35 |
0.25 |
| Age |
-66.01 |
-76.00 |
-56.03 |
5.09 |
4.04e-38 |
| Age^2 |
-5.69 |
-15.38 |
4.00 |
4.94 |
0.25 |
| Mixed or multiple ethnic origins |
0.04 |
-0.58 |
0.66 |
0.32 |
0.90 |
| Asian or Asian British |
-0.03 |
-1.03 |
0.97 |
0.51 |
0.95 |
| African or African British |
-0.38 |
-1.89 |
1.13 |
0.77 |
0.62 |
| Other ethnicity |
0.39 |
-0.56 |
1.33 |
0.48 |
0.42 |
| Key worker |
-0.23 |
-0.42 |
-0.05 |
0.09 |
0.01 |
| Time difference: Lockdown to baseline |
0.00 |
-0.05 |
0.06 |
0.03 |
0.87 |
| 11165 |
0.01 |
0.01 |
11.04 |
2.61e-12 |
6 |
GAD prepan: sensitivity
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline #### Subset of participants 3 months prior to pandemic
| Intercept |
2.34 |
-0.05 |
4.72 |
1.21 |
0.05 |
| gad.sum_score_prepan |
0.54 |
0.49 |
0.60 |
0.03 |
1.22e-63 |
| Depressive and anxiety disorder |
0.73 |
-0.92 |
2.38 |
0.84 |
0.39 |
| Only depressive disorder |
-0.27 |
-2.04 |
1.51 |
0.90 |
0.77 |
| Only anxiety disorder |
0.11 |
-1.87 |
2.08 |
1.01 |
0.92 |
| Eating disorders |
0.88 |
-0.16 |
1.92 |
0.53 |
0.10 |
| OCDs |
0.03 |
-1.02 |
1.08 |
0.54 |
0.96 |
| Psychotic and bipolar disorder |
-0.81 |
-3.33 |
1.71 |
1.28 |
0.53 |
| Only psychotic disorder |
0.37 |
-2.23 |
2.96 |
1.32 |
0.78 |
| Only bipolar disorder |
-0.53 |
-2.17 |
1.11 |
0.84 |
0.53 |
| PTSD |
2.02 |
1.06 |
2.98 |
0.49 |
3.84e-05 |
| ASD |
1.10 |
-0.73 |
2.92 |
0.93 |
0.24 |
| ADHD |
-0.19 |
-2.74 |
2.36 |
1.30 |
0.88 |
| Personality disorder |
-0.51 |
-1.83 |
0.80 |
0.67 |
0.44 |
| Female |
0.64 |
-0.22 |
1.49 |
0.44 |
0.14 |
| Non-binary/Self-defined |
-0.79 |
-3.92 |
2.33 |
1.59 |
0.62 |
| age_category_collapsed_reordered16-18 |
1.36 |
-0.51 |
3.22 |
0.95 |
0.15 |
| 19-25 years |
0.83 |
-0.44 |
2.10 |
0.64 |
0.20 |
| 36-45 years |
-0.05 |
-1.11 |
1.01 |
0.54 |
0.93 |
| 46-55 years |
-0.36 |
-1.42 |
0.70 |
0.54 |
0.50 |
| 56-65 years |
-0.27 |
-1.38 |
0.84 |
0.56 |
0.63 |
| 66-70 years |
-1.36 |
-3.33 |
0.61 |
1.00 |
0.17 |
| 71-75 years |
-0.92 |
-3.73 |
1.88 |
1.43 |
0.52 |
| 76+ years |
0.39 |
-3.07 |
3.86 |
1.76 |
0.82 |
| Mixed or multiple ethnic origins |
-0.49 |
-2.75 |
1.78 |
1.15 |
0.67 |
| Asian or Asian British |
-0.18 |
-3.79 |
3.43 |
1.84 |
0.92 |
| African or African British |
-3.14 |
-7.41 |
1.13 |
2.18 |
0.15 |
| Other ethnicity |
0.61 |
-3.62 |
4.84 |
2.16 |
0.78 |
| Key worker |
0.25 |
-0.48 |
0.97 |
0.37 |
0.50 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.18 |
0.16 |
0.09 |
0.89 |
| 828 |
0.01 |
0.00 |
1.47 |
0.18 |
6 |
Subset of participants 6 months prior to pandemic
| Intercept |
2.12 |
0.46 |
3.79 |
0.85 |
0.01 |
| gad.sum_score_prepan |
0.54 |
0.50 |
0.58 |
0.02 |
1.01e-128 |
| Depressive and anxiety disorder |
0.82 |
-0.26 |
1.90 |
0.55 |
0.14 |
| Only depressive disorder |
-0.20 |
-1.39 |
0.98 |
0.60 |
0.74 |
| Only anxiety disorder |
0.31 |
-0.99 |
1.62 |
0.66 |
0.64 |
| Eating disorders |
0.55 |
-0.20 |
1.30 |
0.38 |
0.15 |
| OCDs |
0.58 |
-0.12 |
1.28 |
0.36 |
0.11 |
| Psychotic and bipolar disorder |
-0.47 |
-2.50 |
1.56 |
1.03 |
0.65 |
| Only psychotic disorder |
0.47 |
-1.08 |
2.02 |
0.79 |
0.55 |
| Only bipolar disorder |
-0.10 |
-1.15 |
0.96 |
0.54 |
0.85 |
| PTSD |
1.73 |
1.07 |
2.40 |
0.34 |
4.05e-07 |
| ASD |
0.33 |
-1.04 |
1.69 |
0.70 |
0.64 |
| ADHD |
-0.61 |
-2.22 |
1.00 |
0.82 |
0.46 |
| Personality disorder |
0.51 |
-0.40 |
1.43 |
0.47 |
0.27 |
| Female |
0.58 |
-0.02 |
1.18 |
0.31 |
0.06 |
| Non-binary/Self-defined |
0.94 |
-0.98 |
2.86 |
0.98 |
0.34 |
| age_category_collapsed_reordered16-18 |
1.26 |
0.11 |
2.41 |
0.59 |
0.03 |
| 19-25 years |
0.90 |
0.02 |
1.78 |
0.45 |
0.04 |
| 36-45 years |
-0.28 |
-1.03 |
0.47 |
0.38 |
0.47 |
| 46-55 years |
-0.59 |
-1.33 |
0.15 |
0.38 |
0.12 |
| 56-65 years |
-0.46 |
-1.26 |
0.33 |
0.40 |
0.25 |
| 66-70 years |
-1.02 |
-2.36 |
0.31 |
0.68 |
0.13 |
| 71-75 years |
-1.42 |
-3.01 |
0.17 |
0.81 |
0.08 |
| 76+ years |
0.41 |
-2.05 |
2.87 |
1.25 |
0.74 |
| Mixed or multiple ethnic origins |
0.71 |
-0.84 |
2.27 |
0.79 |
0.37 |
| Asian or Asian British |
-0.71 |
-2.78 |
1.36 |
1.06 |
0.50 |
| African or African British |
-3.09 |
-6.58 |
0.40 |
1.78 |
0.08 |
| Other ethnicity |
-0.37 |
-2.84 |
2.10 |
1.26 |
0.77 |
| Key worker |
0.06 |
-0.43 |
0.56 |
0.25 |
0.80 |
| Time difference: Lockdown to baseline |
0.00 |
-0.14 |
0.13 |
0.07 |
0.95 |
| 1634 |
0.00 |
0.00 |
1.22 |
0.29 |
6 |
Subset of participants 9 months prior to pandemic
| Intercept |
2.69 |
1.39 |
4.00 |
0.67 |
5.44e-05 |
| gad.sum_score_prepan |
0.53 |
0.50 |
0.57 |
0.02 |
6.23e-209 |
| Depressive and anxiety disorder |
1.03 |
0.18 |
1.89 |
0.44 |
0.02 |
| Only depressive disorder |
0.23 |
-0.70 |
1.15 |
0.47 |
0.63 |
| Only anxiety disorder |
0.50 |
-0.54 |
1.54 |
0.53 |
0.34 |
| Eating disorders |
0.91 |
0.34 |
1.49 |
0.29 |
0.002 |
| OCDs |
0.57 |
0.03 |
1.12 |
0.28 |
0.04 |
| Psychotic and bipolar disorder |
-0.68 |
-2.19 |
0.82 |
0.77 |
0.37 |
| Only psychotic disorder |
0.74 |
-0.47 |
1.95 |
0.62 |
0.23 |
| Only bipolar disorder |
0.21 |
-0.59 |
1.02 |
0.41 |
0.60 |
| PTSD |
1.36 |
0.85 |
1.87 |
0.26 |
1.51e-07 |
| ASD |
0.07 |
-0.99 |
1.13 |
0.54 |
0.90 |
| ADHD |
-0.62 |
-1.94 |
0.69 |
0.67 |
0.35 |
| Personality disorder |
0.78 |
0.08 |
1.48 |
0.36 |
0.03 |
| Female |
0.42 |
-0.03 |
0.87 |
0.23 |
0.07 |
| Non-binary/Self-defined |
0.99 |
-0.43 |
2.40 |
0.72 |
0.17 |
| age_category_collapsed_reordered16-18 |
1.12 |
0.12 |
2.11 |
0.51 |
0.03 |
| 19-25 years |
0.48 |
-0.21 |
1.17 |
0.35 |
0.17 |
| 36-45 years |
-0.24 |
-0.81 |
0.33 |
0.29 |
0.41 |
| 46-55 years |
-0.53 |
-1.09 |
0.02 |
0.28 |
0.06 |
| 56-65 years |
-0.80 |
-1.40 |
-0.20 |
0.30 |
0.009 |
| 66-70 years |
-1.24 |
-2.22 |
-0.25 |
0.50 |
0.01 |
| 71-75 years |
-1.04 |
-2.22 |
0.15 |
0.60 |
0.09 |
| 76+ years |
-0.61 |
-2.65 |
1.43 |
1.04 |
0.56 |
| Mixed or multiple ethnic origins |
0.84 |
-0.47 |
2.15 |
0.67 |
0.21 |
| Asian or Asian British |
-0.16 |
-1.77 |
1.46 |
0.83 |
0.85 |
| African or African British |
0.84 |
-1.78 |
3.46 |
1.34 |
0.53 |
| Other ethnicity |
-0.38 |
-2.04 |
1.29 |
0.85 |
0.66 |
| Key worker |
-0.05 |
-0.43 |
0.32 |
0.19 |
0.78 |
| Time difference: Lockdown to baseline |
-0.06 |
-0.16 |
0.05 |
0.05 |
0.28 |
| 2710 |
0.01 |
0.00 |
2.99 |
0.007 |
6 |
##KT
GAD retro
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.58 |
2.44 |
2.72 |
0.07 |
9.69e-272 |
| Anxiety disorders |
0.82 |
0.51 |
1.13 |
0.16 |
1.80e-07 |
| Eating disorders |
0.41 |
-0.51 |
1.33 |
0.47 |
0.38 |
| OCDs |
1.10 |
0.32 |
1.88 |
0.40 |
0.006 |
| PTSD |
1.01 |
0.24 |
1.78 |
0.39 |
0.01 |
| Depressive disorders |
0.87 |
0.71 |
1.04 |
0.09 |
4.00e-24 |
| Bipolar disorders |
0.86 |
0.49 |
1.24 |
0.19 |
5.71e-06 |
| 18588 |
0.01 |
0.01 |
18.23 |
3.23e-21 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.58 |
2.45 |
2.71 |
0.07 |
2.17e-303 |
| Depressive and anxiety disorder |
0.85 |
0.68 |
1.03 |
0.09 |
4.94e-21 |
| Only depressive disorder |
0.25 |
0.01 |
0.48 |
0.12 |
0.04 |
| Only anxiety disorder |
0.86 |
0.58 |
1.15 |
0.14 |
2.26e-09 |
| Eating disorders |
0.49 |
0.22 |
0.76 |
0.14 |
4.28e-04 |
| OCDs |
0.05 |
-0.21 |
0.31 |
0.13 |
0.72 |
| Psychotic and bipolar disorder |
-0.20 |
-0.96 |
0.56 |
0.39 |
0.61 |
| Only psychotic disorder |
-0.28 |
-0.94 |
0.38 |
0.34 |
0.41 |
| Only bipolar disorder |
-0.21 |
-0.62 |
0.19 |
0.21 |
0.30 |
| PTSD |
0.41 |
0.17 |
0.66 |
0.12 |
8.72e-04 |
| ASD |
0.36 |
-0.12 |
0.83 |
0.24 |
0.14 |
| ADHD |
0.01 |
-0.63 |
0.64 |
0.32 |
0.99 |
| Personality disorder |
0.29 |
-0.06 |
0.64 |
0.18 |
0.11 |
| 18588 |
0.01 |
0.01 |
18.23 |
3.23e-21 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.16 |
3.79 |
4.52 |
0.19 |
4.36e-106 |
| Anxiety disorders |
0.57 |
0.25 |
0.90 |
0.17 |
5.51e-04 |
| Eating disorders |
0.02 |
-0.91 |
0.96 |
0.48 |
0.96 |
| OCDs |
0.54 |
-0.25 |
1.34 |
0.41 |
0.18 |
| PTSD |
0.78 |
-0.02 |
1.58 |
0.41 |
0.06 |
| Depressive disorders |
0.63 |
0.45 |
0.82 |
0.10 |
3.17e-11 |
| Bipolar disorders |
0.65 |
0.26 |
1.03 |
0.20 |
9.77e-04 |
| Female |
0.77 |
0.57 |
0.97 |
0.10 |
2.26e-14 |
| Non-binary/Self-defined |
-0.24 |
-0.90 |
0.42 |
0.34 |
0.48 |
| age_category_collapsed_reordered16-18 |
-0.31 |
-0.74 |
0.11 |
0.22 |
0.15 |
| 19-25 years |
0.70 |
0.41 |
0.99 |
0.15 |
3.16e-06 |
| 36-45 years |
-0.49 |
-0.75 |
-0.24 |
0.13 |
1.58e-04 |
| 46-55 years |
-0.69 |
-0.93 |
-0.45 |
0.12 |
2.15e-08 |
| 56-65 years |
-0.84 |
-1.09 |
-0.60 |
0.12 |
1.18e-11 |
| 66-70 years |
-1.13 |
-1.49 |
-0.78 |
0.18 |
4.01e-10 |
| 71-75 years |
-1.54 |
-1.97 |
-1.10 |
0.22 |
4.82e-12 |
| 76+ years |
-1.84 |
-2.60 |
-1.09 |
0.38 |
1.69e-06 |
| Mixed or multiple ethnic origins |
-0.65 |
-1.19 |
-0.11 |
0.28 |
0.02 |
| Asian or Asian British |
-0.45 |
-1.16 |
0.26 |
0.36 |
0.22 |
| African or African British |
-0.56 |
-1.73 |
0.62 |
0.60 |
0.35 |
| Other ethnicity |
-0.03 |
-0.99 |
0.93 |
0.49 |
0.95 |
| Time difference: Lockdown to baseline |
-0.23 |
-0.26 |
-0.19 |
0.02 |
5.86e-34 |
| 18588 |
0.01 |
0.01 |
18.23 |
3.23e-21 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.94 |
3.57 |
4.31 |
0.19 |
2.84e-95 |
| Depressive and anxiety disorder |
0.65 |
0.46 |
0.85 |
0.10 |
4.95e-11 |
| Only depressive disorder |
0.25 |
0.00 |
0.51 |
0.13 |
0.05 |
| Only anxiety disorder |
0.63 |
0.34 |
0.93 |
0.15 |
2.96e-05 |
| Eating disorders |
0.29 |
0.01 |
0.56 |
0.14 |
0.04 |
| OCDs |
-0.09 |
-0.36 |
0.17 |
0.14 |
0.50 |
| Psychotic and bipolar disorder |
0.09 |
-0.67 |
0.86 |
0.39 |
0.81 |
| Only psychotic disorder |
-0.05 |
-0.71 |
0.62 |
0.34 |
0.89 |
| Only bipolar disorder |
-0.11 |
-0.52 |
0.30 |
0.21 |
0.60 |
| PTSD |
0.43 |
0.18 |
0.68 |
0.13 |
6.93e-04 |
| ASD |
0.36 |
-0.13 |
0.85 |
0.25 |
0.15 |
| ADHD |
-0.06 |
-0.70 |
0.58 |
0.33 |
0.86 |
| Personality disorder |
0.18 |
-0.18 |
0.54 |
0.18 |
0.32 |
| Female |
0.73 |
0.53 |
0.93 |
0.10 |
4.31e-13 |
| Non-binary/Self-defined |
-0.32 |
-0.98 |
0.34 |
0.34 |
0.35 |
| age_category_collapsed_reordered16-18 |
-0.20 |
-0.62 |
0.22 |
0.21 |
0.35 |
| 19-25 years |
0.74 |
0.45 |
1.03 |
0.15 |
7.36e-07 |
| 36-45 years |
-0.49 |
-0.75 |
-0.24 |
0.13 |
1.43e-04 |
| 46-55 years |
-0.67 |
-0.91 |
-0.43 |
0.12 |
5.39e-08 |
| 56-65 years |
-0.72 |
-0.96 |
-0.47 |
0.13 |
1.26e-08 |
| 66-70 years |
-0.87 |
-1.23 |
-0.50 |
0.18 |
2.68e-06 |
| 71-75 years |
-1.28 |
-1.72 |
-0.84 |
0.22 |
1.32e-08 |
| 76+ years |
-1.57 |
-2.31 |
-0.82 |
0.38 |
3.88e-05 |
| Mixed or multiple ethnic origins |
-0.57 |
-1.10 |
-0.04 |
0.27 |
0.04 |
| Asian or Asian British |
-0.22 |
-0.90 |
0.46 |
0.35 |
0.53 |
| African or African British |
-0.63 |
-1.80 |
0.53 |
0.59 |
0.29 |
| Other ethnicity |
-0.10 |
-1.04 |
0.83 |
0.48 |
0.83 |
| Key worker |
0.31 |
0.15 |
0.48 |
0.08 |
1.21e-04 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.26 |
-0.19 |
0.02 |
4.99e-34 |
| 18588 |
0.01 |
0.01 |
18.23 |
3.23e-21 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.11 |
1.67 |
2.55 |
0.22 |
4.09e-21 |
| Anxiety disorders |
0.54 |
0.13 |
0.95 |
0.21 |
0.010 |
| Eating disorders |
0.38 |
-0.80 |
1.56 |
0.60 |
0.52 |
| OCDs |
0.30 |
-0.73 |
1.34 |
0.53 |
0.57 |
| PTSD |
1.17 |
0.06 |
2.28 |
0.57 |
0.04 |
| Depressive disorders |
0.95 |
0.72 |
1.18 |
0.12 |
1.36e-15 |
| Bipolar disorders |
1.00 |
0.56 |
1.44 |
0.22 |
7.90e-06 |
| Female |
0.64 |
0.41 |
0.86 |
0.11 |
2.52e-08 |
| Non-binary/Self-defined |
-0.60 |
-1.34 |
0.14 |
0.38 |
0.11 |
| Age |
-78.52 |
-90.65 |
-66.40 |
6.19 |
1.10e-36 |
| Age^2 |
7.26 |
-4.22 |
18.74 |
5.86 |
0.22 |
| Mixed or multiple ethnic origins |
-0.67 |
-1.30 |
-0.04 |
0.32 |
0.04 |
| Asian or Asian British |
-0.22 |
-1.14 |
0.69 |
0.47 |
0.63 |
| African or African British |
-0.67 |
-2.12 |
0.79 |
0.74 |
0.37 |
| Other ethnicity |
0.16 |
-0.97 |
1.29 |
0.58 |
0.78 |
| Time difference: Lockdown to baseline |
-0.07 |
-0.12 |
-0.02 |
0.03 |
0.007 |
| 13420 |
0.01 |
0.01 |
30.14 |
4.04e-36 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.99 |
1.55 |
2.43 |
0.22 |
5.70e-19 |
| Depressive and anxiety disorder |
0.95 |
0.71 |
1.18 |
0.12 |
5.37e-15 |
| Only depressive disorder |
0.48 |
0.17 |
0.79 |
0.16 |
0.002 |
| Only anxiety disorder |
0.60 |
0.22 |
0.98 |
0.19 |
0.002 |
| Eating disorders |
0.26 |
-0.05 |
0.58 |
0.16 |
0.10 |
| OCDs |
-0.27 |
-0.57 |
0.03 |
0.15 |
0.08 |
| Psychotic and bipolar disorder |
0.33 |
-0.58 |
1.23 |
0.46 |
0.48 |
| Only psychotic disorder |
-0.06 |
-0.81 |
0.68 |
0.38 |
0.87 |
| Only bipolar disorder |
-0.12 |
-0.56 |
0.33 |
0.23 |
0.61 |
| PTSD |
0.58 |
0.30 |
0.86 |
0.14 |
5.60e-05 |
| ASD |
0.15 |
-0.44 |
0.73 |
0.30 |
0.62 |
| ADHD |
0.09 |
-0.69 |
0.88 |
0.40 |
0.82 |
| Personality disorder |
0.31 |
-0.09 |
0.71 |
0.20 |
0.13 |
| Female |
0.57 |
0.35 |
0.79 |
0.11 |
5.73e-07 |
| Non-binary/Self-defined |
-0.73 |
-1.46 |
0.01 |
0.38 |
0.05 |
| Age |
-71.01 |
-83.47 |
-58.55 |
6.35 |
7.47e-29 |
| Age^2 |
14.88 |
3.18 |
26.59 |
5.97 |
0.01 |
| Mixed or multiple ethnic origins |
-0.62 |
-1.24 |
0.01 |
0.32 |
0.05 |
| Asian or Asian British |
-0.10 |
-0.99 |
0.79 |
0.45 |
0.82 |
| African or African British |
-0.68 |
-2.13 |
0.77 |
0.74 |
0.36 |
| Other ethnicity |
-0.04 |
-1.15 |
1.06 |
0.56 |
0.94 |
| Key worker |
0.33 |
0.14 |
0.51 |
0.09 |
4.57e-04 |
| Time difference: Lockdown to baseline |
-0.07 |
-0.12 |
-0.02 |
0.03 |
0.009 |
| 13420 |
0.01 |
0.01 |
30.14 |
4.04e-36 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.53 |
3.40 |
3.67 |
0.07 |
0.00e+00 |
| gad.sum_score_retro |
0.61 |
0.59 |
0.62 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.81 |
1.52 |
2.11 |
0.15 |
1.59e-33 |
| Eating disorders |
1.26 |
0.40 |
2.13 |
0.44 |
0.004 |
| OCDs |
2.70 |
1.97 |
3.44 |
0.38 |
5.91e-13 |
| PTSD |
2.16 |
1.43 |
2.88 |
0.37 |
5.60e-09 |
| Depressive disorders |
2.28 |
2.11 |
2.45 |
0.09 |
1.24e-151 |
| Bipolar disorders |
2.94 |
2.57 |
3.30 |
0.18 |
7.53e-57 |
| 18588 |
0.32 |
0.32 |
1276.84 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
3.75 |
3.62 |
3.88 |
0.07 |
0.00e+00 |
| gad.sum_score_retro |
0.55 |
0.54 |
0.57 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.31 |
2.14 |
2.49 |
0.09 |
3.78e-148 |
| Only depressive disorder |
0.67 |
0.45 |
0.89 |
0.11 |
2.55e-09 |
| Only anxiety disorder |
1.89 |
1.63 |
2.16 |
0.14 |
4.35e-44 |
| Eating disorders |
0.78 |
0.53 |
1.03 |
0.13 |
1.83e-09 |
| OCDs |
0.75 |
0.50 |
0.99 |
0.12 |
2.15e-09 |
| Psychotic and bipolar disorder |
0.10 |
-0.60 |
0.81 |
0.36 |
0.77 |
| Only psychotic disorder |
0.03 |
-0.58 |
0.65 |
0.31 |
0.92 |
| Only bipolar disorder |
0.16 |
-0.21 |
0.54 |
0.19 |
0.40 |
| PTSD |
0.84 |
0.61 |
1.07 |
0.12 |
3.49e-13 |
| ASD |
1.02 |
0.58 |
1.46 |
0.22 |
6.19e-06 |
| ADHD |
0.44 |
-0.15 |
1.03 |
0.30 |
0.14 |
| Personality disorder |
1.09 |
0.76 |
1.42 |
0.17 |
6.62e-11 |
| 23100 |
0.15 |
0.15 |
660.52 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.56 |
5.21 |
5.92 |
0.18 |
3.96e-203 |
| gad.sum_score_retro |
0.56 |
0.54 |
0.57 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.48 |
1.18 |
1.79 |
0.15 |
1.29e-21 |
| Eating disorders |
0.78 |
-0.09 |
1.65 |
0.44 |
0.08 |
| OCDs |
1.91 |
1.17 |
2.65 |
0.38 |
4.63e-07 |
| PTSD |
1.98 |
1.24 |
2.73 |
0.38 |
1.86e-07 |
| Depressive disorders |
2.07 |
1.89 |
2.25 |
0.09 |
2.61e-109 |
| Bipolar disorders |
2.77 |
2.40 |
3.14 |
0.19 |
2.68e-49 |
| Female |
0.76 |
0.57 |
0.94 |
0.09 |
7.47e-16 |
| Non-binary/Self-defined |
0.28 |
-0.34 |
0.90 |
0.31 |
0.37 |
| age_category_collapsed_reordered16-18 |
1.04 |
0.64 |
1.44 |
0.21 |
3.81e-07 |
| 19-25 years |
0.99 |
0.72 |
1.26 |
0.14 |
1.49e-12 |
| 36-45 years |
-0.59 |
-0.82 |
-0.35 |
0.12 |
1.18e-06 |
| 46-55 years |
-0.93 |
-1.15 |
-0.70 |
0.11 |
4.53e-16 |
| 56-65 years |
-1.38 |
-1.61 |
-1.15 |
0.12 |
3.41e-32 |
| 66-70 years |
-1.89 |
-2.23 |
-1.56 |
0.17 |
4.01e-28 |
| 71-75 years |
-2.34 |
-2.75 |
-1.93 |
0.21 |
8.42e-29 |
| 76+ years |
-2.38 |
-3.08 |
-1.68 |
0.36 |
3.47e-11 |
| Mixed or multiple ethnic origins |
-0.40 |
-0.90 |
0.10 |
0.26 |
0.12 |
| Asian or Asian British |
-0.28 |
-0.94 |
0.38 |
0.34 |
0.40 |
| African or African British |
-0.20 |
-1.29 |
0.89 |
0.56 |
0.72 |
| Other ethnicity |
0.27 |
-0.62 |
1.16 |
0.46 |
0.56 |
| Key worker |
-0.04 |
-0.19 |
0.11 |
0.08 |
0.58 |
| Time difference: Lockdown to baseline |
-0.23 |
-0.26 |
-0.19 |
0.02 |
3.80e-39 |
| 23100 |
0.15 |
0.15 |
660.52 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.56 |
5.22 |
5.91 |
0.18 |
3.62e-213 |
| gad.sum_score_retro |
0.51 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.15 |
1.96 |
2.33 |
0.09 |
2.61e-112 |
| Only depressive disorder |
0.79 |
0.55 |
1.02 |
0.12 |
3.46e-11 |
| Only anxiety disorder |
1.61 |
1.33 |
1.89 |
0.14 |
2.57e-30 |
| Eating disorders |
0.52 |
0.26 |
0.77 |
0.13 |
7.02e-05 |
| OCDs |
0.57 |
0.33 |
0.82 |
0.13 |
5.06e-06 |
| Psychotic and bipolar disorder |
0.42 |
-0.28 |
1.12 |
0.36 |
0.24 |
| Only psychotic disorder |
0.26 |
-0.36 |
0.87 |
0.31 |
0.41 |
| Only bipolar disorder |
0.30 |
-0.08 |
0.67 |
0.19 |
0.13 |
| PTSD |
0.92 |
0.69 |
1.15 |
0.12 |
3.17e-15 |
| ASD |
0.78 |
0.33 |
1.23 |
0.23 |
6.65e-04 |
| ADHD |
0.25 |
-0.34 |
0.84 |
0.30 |
0.41 |
| Personality disorder |
1.00 |
0.67 |
1.33 |
0.17 |
2.56e-09 |
| Female |
0.70 |
0.52 |
0.88 |
0.09 |
2.87e-14 |
| Non-binary/Self-defined |
-0.11 |
-0.71 |
0.50 |
0.31 |
0.73 |
| age_category_collapsed_reordered16-18 |
1.27 |
0.88 |
1.66 |
0.20 |
1.25e-10 |
| 19-25 years |
1.00 |
0.73 |
1.27 |
0.14 |
3.03e-13 |
| 36-45 years |
-0.53 |
-0.77 |
-0.30 |
0.12 |
7.90e-06 |
| 46-55 years |
-0.77 |
-0.99 |
-0.55 |
0.11 |
9.25e-12 |
| 56-65 years |
-1.11 |
-1.33 |
-0.88 |
0.12 |
1.24e-21 |
| 66-70 years |
-1.52 |
-1.85 |
-1.19 |
0.17 |
4.00e-19 |
| 71-75 years |
-1.93 |
-2.33 |
-1.52 |
0.21 |
1.12e-20 |
| 76+ years |
-1.98 |
-2.67 |
-1.30 |
0.35 |
1.48e-08 |
| Mixed or multiple ethnic origins |
-0.30 |
-0.79 |
0.19 |
0.25 |
0.23 |
| Asian or Asian British |
0.08 |
-0.55 |
0.71 |
0.32 |
0.81 |
| African or African British |
-0.17 |
-1.24 |
0.90 |
0.55 |
0.75 |
| Other ethnicity |
0.19 |
-0.68 |
1.05 |
0.44 |
0.67 |
| Key worker |
0.05 |
-0.10 |
0.19 |
0.08 |
0.53 |
| Time difference: Lockdown to baseline |
-0.23 |
-0.27 |
-0.20 |
0.02 |
2.32e-42 |
| 23100 |
0.15 |
0.15 |
660.52 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.86 |
2.45 |
3.27 |
0.21 |
3.52e-42 |
| gad.sum_score_retro |
0.55 |
0.53 |
0.57 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.53 |
1.14 |
1.91 |
0.19 |
4.59e-15 |
| Eating disorders |
1.29 |
0.21 |
2.37 |
0.55 |
0.02 |
| OCDs |
2.09 |
1.14 |
3.05 |
0.49 |
1.75e-05 |
| PTSD |
2.58 |
1.56 |
3.61 |
0.52 |
7.56e-07 |
| Depressive disorders |
2.53 |
2.31 |
2.75 |
0.11 |
1.56e-106 |
| Bipolar disorders |
3.23 |
2.81 |
3.64 |
0.21 |
5.28e-52 |
| Female |
0.58 |
0.37 |
0.79 |
0.11 |
3.42e-08 |
| Non-binary/Self-defined |
-0.04 |
-0.72 |
0.64 |
0.35 |
0.91 |
| Age |
-121.62 |
-133.06 |
-110.18 |
5.84 |
8.19e-95 |
| Age^2 |
10.80 |
-0.08 |
21.68 |
5.55 |
0.05 |
| Mixed or multiple ethnic origins |
-0.45 |
-1.03 |
0.13 |
0.30 |
0.13 |
| Asian or Asian British |
0.08 |
-0.76 |
0.93 |
0.43 |
0.85 |
| African or African British |
-0.07 |
-1.41 |
1.27 |
0.68 |
0.92 |
| Other ethnicity |
0.55 |
-0.49 |
1.59 |
0.53 |
0.30 |
| Key worker |
-0.05 |
-0.22 |
0.12 |
0.09 |
0.57 |
| Time difference: Lockdown to baseline |
-0.02 |
-0.07 |
0.02 |
0.02 |
0.34 |
| 16839 |
0.19 |
0.19 |
657.64 |
0.00e+00 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.95 |
2.55 |
3.35 |
0.20 |
7.90e-47 |
| gad.sum_score_retro |
0.51 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.57 |
2.34 |
2.79 |
0.11 |
2.83e-109 |
| Only depressive disorder |
1.14 |
0.85 |
1.42 |
0.14 |
4.22e-15 |
| Only anxiety disorder |
1.70 |
1.35 |
2.05 |
0.18 |
7.64e-22 |
| Eating disorders |
0.58 |
0.30 |
0.87 |
0.15 |
7.13e-05 |
| OCDs |
0.40 |
0.12 |
0.67 |
0.14 |
0.004 |
| Psychotic and bipolar disorder |
0.39 |
-0.44 |
1.21 |
0.42 |
0.36 |
| Only psychotic disorder |
0.34 |
-0.34 |
1.02 |
0.35 |
0.32 |
| Only bipolar disorder |
0.32 |
-0.09 |
0.73 |
0.21 |
0.12 |
| PTSD |
1.06 |
0.81 |
1.32 |
0.13 |
5.80e-16 |
| ASD |
0.64 |
0.11 |
1.17 |
0.27 |
0.02 |
| ADHD |
0.40 |
-0.32 |
1.11 |
0.36 |
0.28 |
| Personality disorder |
1.04 |
0.68 |
1.41 |
0.19 |
2.32e-08 |
| Female |
0.48 |
0.28 |
0.69 |
0.10 |
3.22e-06 |
| Non-binary/Self-defined |
-0.43 |
-1.10 |
0.24 |
0.34 |
0.21 |
| Age |
-106.45 |
-117.87 |
-95.03 |
5.83 |
1.31e-73 |
| Age^2 |
15.07 |
4.41 |
25.72 |
5.44 |
0.006 |
| Mixed or multiple ethnic origins |
-0.41 |
-0.98 |
0.16 |
0.29 |
0.16 |
| Asian or Asian British |
0.28 |
-0.53 |
1.09 |
0.41 |
0.50 |
| African or African British |
-0.07 |
-1.39 |
1.25 |
0.67 |
0.92 |
| Other ethnicity |
0.38 |
-0.63 |
1.38 |
0.51 |
0.46 |
| Key worker |
0.06 |
-0.11 |
0.23 |
0.09 |
0.48 |
| Time difference: Lockdown to baseline |
-0.02 |
-0.06 |
0.03 |
0.02 |
0.47 |
| 16839 |
0.19 |
0.19 |
657.64 |
0.00e+00 |
6 |
GAD retro: sensitivity
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.16 |
1.00 |
3.32 |
0.59 |
2.65e-04 |
| Anxiety disorders |
1.11 |
-0.16 |
2.38 |
0.65 |
0.09 |
| Eating disorders |
1.99 |
-0.40 |
4.38 |
1.22 |
0.10 |
| OCDs |
1.16 |
-0.57 |
2.88 |
0.88 |
0.19 |
| PTSD |
1.80 |
-0.09 |
3.70 |
0.97 |
0.06 |
| Depressive disorders |
1.19 |
0.03 |
2.36 |
0.60 |
0.05 |
| Bipolar disorders |
1.05 |
-0.20 |
2.30 |
0.64 |
0.10 |
| 8058 |
0.00 |
0.00 |
0.94 |
0.47 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.55 |
1.72 |
3.38 |
0.42 |
1.97e-09 |
| Depressive and anxiety disorder |
0.73 |
-0.11 |
1.57 |
0.43 |
0.09 |
| Only depressive disorder |
0.15 |
-0.76 |
1.07 |
0.47 |
0.74 |
| Only anxiety disorder |
0.84 |
-0.11 |
1.78 |
0.48 |
0.08 |
| Eating disorders |
0.55 |
0.16 |
0.93 |
0.20 |
0.006 |
| OCDs |
-0.21 |
-0.57 |
0.15 |
0.18 |
0.25 |
| Psychotic and bipolar disorder |
-0.30 |
-1.39 |
0.79 |
0.56 |
0.59 |
| Only psychotic disorder |
-0.16 |
-1.07 |
0.74 |
0.46 |
0.73 |
| Only bipolar disorder |
-0.29 |
-0.83 |
0.24 |
0.27 |
0.28 |
| PTSD |
0.39 |
0.06 |
0.73 |
0.17 |
0.02 |
| ASD |
0.22 |
-0.49 |
0.92 |
0.36 |
0.55 |
| ADHD |
0.12 |
-0.86 |
1.09 |
0.50 |
0.81 |
| Personality disorder |
0.42 |
-0.06 |
0.90 |
0.24 |
0.09 |
| 8058 |
0.00 |
0.00 |
0.94 |
0.47 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.52 |
1.18 |
3.86 |
0.68 |
2.21e-04 |
| Anxiety disorders |
0.99 |
-0.27 |
2.25 |
0.64 |
0.12 |
| Eating disorders |
1.69 |
-0.69 |
4.06 |
1.21 |
0.16 |
| OCDs |
0.90 |
-0.81 |
2.61 |
0.87 |
0.30 |
| PTSD |
1.94 |
0.06 |
3.82 |
0.96 |
0.04 |
| Depressive disorders |
1.23 |
0.06 |
2.39 |
0.59 |
0.04 |
| Bipolar disorders |
1.17 |
-0.08 |
2.41 |
0.63 |
0.07 |
| Female |
0.67 |
0.33 |
1.01 |
0.17 |
1.22e-04 |
| Non-binary/Self-defined |
-0.64 |
-1.56 |
0.28 |
0.47 |
0.17 |
| age_category_collapsed_reordered16-18 |
-0.22 |
-0.99 |
0.54 |
0.39 |
0.57 |
| 19-25 years |
0.72 |
0.31 |
1.12 |
0.21 |
6.13e-04 |
| 36-45 years |
-0.46 |
-0.82 |
-0.09 |
0.19 |
0.01 |
| 46-55 years |
-0.66 |
-1.02 |
-0.30 |
0.18 |
3.10e-04 |
| 56-65 years |
-1.17 |
-1.58 |
-0.75 |
0.21 |
2.79e-08 |
| 66-70 years |
-1.42 |
-2.20 |
-0.65 |
0.40 |
3.24e-04 |
| 71-75 years |
-2.06 |
-3.10 |
-1.02 |
0.53 |
1.11e-04 |
| 76+ years |
-2.91 |
-5.13 |
-0.69 |
1.13 |
0.01 |
| Mixed or multiple ethnic origins |
-0.80 |
-1.63 |
0.03 |
0.42 |
0.06 |
| Asian or Asian British |
0.11 |
-1.24 |
1.47 |
0.69 |
0.87 |
| African or African British |
-1.27 |
-3.25 |
0.71 |
1.01 |
0.21 |
| Other ethnicity |
0.05 |
-1.26 |
1.36 |
0.67 |
0.94 |
| Time difference: Lockdown to baseline |
-0.07 |
-0.15 |
0.00 |
0.04 |
0.05 |
| 8058 |
0.00 |
0.00 |
0.94 |
0.47 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.81 |
1.73 |
3.89 |
0.55 |
3.49e-07 |
| Depressive and anxiety disorder |
0.71 |
-0.14 |
1.55 |
0.43 |
0.10 |
| Only depressive disorder |
0.37 |
-0.54 |
1.29 |
0.47 |
0.43 |
| Only anxiety disorder |
0.67 |
-0.27 |
1.62 |
0.48 |
0.16 |
| Eating disorders |
0.37 |
-0.02 |
0.76 |
0.20 |
0.06 |
| OCDs |
-0.27 |
-0.63 |
0.09 |
0.18 |
0.15 |
| Psychotic and bipolar disorder |
0.03 |
-1.05 |
1.12 |
0.55 |
0.95 |
| Only psychotic disorder |
0.11 |
-0.80 |
1.02 |
0.46 |
0.81 |
| Only bipolar disorder |
-0.17 |
-0.70 |
0.37 |
0.27 |
0.54 |
| PTSD |
0.46 |
0.12 |
0.80 |
0.17 |
0.008 |
| ASD |
0.25 |
-0.46 |
0.96 |
0.36 |
0.50 |
| ADHD |
0.21 |
-0.76 |
1.18 |
0.50 |
0.67 |
| Personality disorder |
0.29 |
-0.19 |
0.77 |
0.24 |
0.23 |
| Female |
0.59 |
0.25 |
0.93 |
0.17 |
7.07e-04 |
| Non-binary/Self-defined |
-0.76 |
-1.68 |
0.16 |
0.47 |
0.10 |
| age_category_collapsed_reordered16-18 |
-0.09 |
-0.86 |
0.67 |
0.39 |
0.81 |
| 19-25 years |
0.74 |
0.33 |
1.15 |
0.21 |
3.64e-04 |
| 36-45 years |
-0.44 |
-0.81 |
-0.08 |
0.19 |
0.02 |
| 46-55 years |
-0.65 |
-1.01 |
-0.29 |
0.18 |
4.23e-04 |
| 56-65 years |
-1.05 |
-1.47 |
-0.64 |
0.21 |
6.77e-07 |
| 66-70 years |
-1.22 |
-2.01 |
-0.44 |
0.40 |
0.002 |
| 71-75 years |
-1.69 |
-2.74 |
-0.65 |
0.53 |
0.001 |
| 76+ years |
-2.61 |
-4.83 |
-0.39 |
1.13 |
0.02 |
| Mixed or multiple ethnic origins |
-0.74 |
-1.57 |
0.09 |
0.42 |
0.08 |
| Asian or Asian British |
0.14 |
-1.20 |
1.49 |
0.69 |
0.83 |
| African or African British |
-1.24 |
-3.21 |
0.74 |
1.01 |
0.22 |
| Other ethnicity |
-0.14 |
-1.42 |
1.14 |
0.65 |
0.83 |
| Key worker |
0.36 |
0.11 |
0.61 |
0.13 |
0.005 |
| Time difference: Lockdown to baseline |
-0.07 |
-0.15 |
0.00 |
0.04 |
0.06 |
| 8058 |
0.00 |
0.00 |
0.94 |
0.47 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
4.62 |
3.56 |
5.69 |
0.54 |
2.04e-17 |
| gad.sum_score_retro |
0.52 |
0.50 |
0.55 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.15 |
0.00 |
2.31 |
0.59 |
0.05 |
| Eating disorders |
2.74 |
0.56 |
4.93 |
1.11 |
0.01 |
| OCDs |
2.21 |
0.64 |
3.78 |
0.80 |
0.006 |
| PTSD |
2.11 |
0.39 |
3.84 |
0.88 |
0.02 |
| Depressive disorders |
1.73 |
0.66 |
2.79 |
0.54 |
0.001 |
| Bipolar disorders |
2.17 |
1.03 |
3.31 |
0.58 |
1.86e-04 |
| 8058 |
0.20 |
0.20 |
290.49 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
5.45 |
4.69 |
6.21 |
0.39 |
2.82e-44 |
| gad.sum_score_retro |
0.48 |
0.46 |
0.51 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.89 |
0.13 |
1.65 |
0.39 |
0.02 |
| Only depressive disorder |
-0.64 |
-1.46 |
0.18 |
0.42 |
0.13 |
| Only anxiety disorder |
0.67 |
-0.18 |
1.52 |
0.43 |
0.12 |
| Eating disorders |
0.88 |
0.53 |
1.23 |
0.18 |
8.46e-07 |
| OCDs |
0.51 |
0.19 |
0.84 |
0.17 |
0.002 |
| Psychotic and bipolar disorder |
-0.33 |
-1.31 |
0.65 |
0.50 |
0.51 |
| Only psychotic disorder |
0.14 |
-0.68 |
0.95 |
0.42 |
0.74 |
| Only bipolar disorder |
0.07 |
-0.41 |
0.55 |
0.25 |
0.77 |
| PTSD |
0.84 |
0.54 |
1.15 |
0.16 |
6.51e-08 |
| ASD |
0.86 |
0.23 |
1.49 |
0.32 |
0.008 |
| ADHD |
0.52 |
-0.36 |
1.39 |
0.45 |
0.25 |
| Personality disorder |
1.26 |
0.83 |
1.69 |
0.22 |
1.31e-08 |
| 9688 |
0.01 |
0.01 |
11.18 |
1.82e-12 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.78 |
3.55 |
6.01 |
0.63 |
2.77e-14 |
| gad.sum_score_retro |
0.50 |
0.48 |
0.53 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.16 |
0.02 |
2.31 |
0.58 |
0.05 |
| Eating disorders |
2.59 |
0.43 |
4.74 |
1.10 |
0.02 |
| OCDs |
2.00 |
0.44 |
3.55 |
0.79 |
0.01 |
| PTSD |
2.51 |
0.80 |
4.22 |
0.87 |
0.004 |
| Depressive disorders |
1.99 |
0.93 |
3.05 |
0.54 |
2.34e-04 |
| Bipolar disorders |
2.54 |
1.40 |
3.67 |
0.58 |
1.17e-05 |
| Female |
0.53 |
0.22 |
0.84 |
0.16 |
7.40e-04 |
| Non-binary/Self-defined |
0.01 |
-0.82 |
0.84 |
0.42 |
0.99 |
| age_category_collapsed_reordered16-18 |
1.11 |
0.41 |
1.81 |
0.36 |
0.002 |
| 19-25 years |
0.99 |
0.61 |
1.36 |
0.19 |
2.01e-07 |
| 36-45 years |
-0.46 |
-0.79 |
-0.12 |
0.17 |
0.007 |
| 46-55 years |
-0.76 |
-1.08 |
-0.43 |
0.17 |
5.19e-06 |
| 56-65 years |
-1.48 |
-1.85 |
-1.10 |
0.19 |
1.13e-14 |
| 66-70 years |
-2.09 |
-2.80 |
-1.37 |
0.36 |
9.14e-09 |
| 71-75 years |
-2.93 |
-3.88 |
-1.98 |
0.48 |
1.50e-09 |
| 76+ years |
-2.70 |
-4.71 |
-0.68 |
1.03 |
0.009 |
| Mixed or multiple ethnic origins |
-0.60 |
-1.35 |
0.15 |
0.38 |
0.12 |
| Asian or Asian British |
0.20 |
-1.03 |
1.43 |
0.63 |
0.75 |
| African or African British |
-0.42 |
-2.21 |
1.37 |
0.91 |
0.64 |
| Other ethnicity |
0.37 |
-0.81 |
1.56 |
0.60 |
0.53 |
| Key worker |
-0.16 |
-0.39 |
0.07 |
0.12 |
0.18 |
| Time difference: Lockdown to baseline |
-0.04 |
-0.11 |
0.03 |
0.03 |
0.30 |
| 9688 |
0.01 |
0.01 |
11.18 |
1.82e-12 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.60 |
4.63 |
6.58 |
0.50 |
3.63e-29 |
| gad.sum_score_retro |
0.47 |
0.45 |
0.49 |
0.01 |
2.49e-310 |
| Depressive and anxiety disorder |
1.03 |
0.27 |
1.79 |
0.39 |
0.008 |
| Only depressive disorder |
-0.21 |
-1.03 |
0.61 |
0.42 |
0.61 |
| Only anxiety disorder |
0.58 |
-0.27 |
1.43 |
0.43 |
0.18 |
| Eating disorders |
0.69 |
0.34 |
1.04 |
0.18 |
1.04e-04 |
| OCDs |
0.42 |
0.10 |
0.75 |
0.17 |
0.01 |
| Psychotic and bipolar disorder |
-0.02 |
-0.99 |
0.95 |
0.50 |
0.97 |
| Only psychotic disorder |
0.34 |
-0.47 |
1.16 |
0.41 |
0.41 |
| Only bipolar disorder |
0.21 |
-0.27 |
0.69 |
0.24 |
0.39 |
| PTSD |
0.94 |
0.63 |
1.24 |
0.16 |
1.62e-09 |
| ASD |
0.65 |
0.01 |
1.29 |
0.32 |
0.05 |
| ADHD |
0.53 |
-0.35 |
1.40 |
0.44 |
0.24 |
| Personality disorder |
1.12 |
0.69 |
1.55 |
0.22 |
3.69e-07 |
| Female |
0.39 |
0.09 |
0.70 |
0.16 |
0.01 |
| Non-binary/Self-defined |
-0.43 |
-1.26 |
0.39 |
0.42 |
0.30 |
| age_category_collapsed_reordered16-18 |
1.20 |
0.51 |
1.88 |
0.35 |
6.43e-04 |
| 19-25 years |
0.99 |
0.62 |
1.35 |
0.19 |
1.31e-07 |
| 36-45 years |
-0.40 |
-0.73 |
-0.07 |
0.17 |
0.02 |
| 46-55 years |
-0.63 |
-0.95 |
-0.31 |
0.17 |
1.41e-04 |
| 56-65 years |
-1.24 |
-1.61 |
-0.87 |
0.19 |
7.82e-11 |
| 66-70 years |
-1.80 |
-2.51 |
-1.10 |
0.36 |
5.13e-07 |
| 71-75 years |
-2.40 |
-3.33 |
-1.46 |
0.48 |
5.09e-07 |
| 76+ years |
-2.27 |
-4.26 |
-0.28 |
1.01 |
0.03 |
| Mixed or multiple ethnic origins |
-0.56 |
-1.30 |
0.18 |
0.38 |
0.14 |
| Asian or Asian British |
0.30 |
-0.91 |
1.51 |
0.62 |
0.63 |
| African or African British |
-0.32 |
-2.10 |
1.45 |
0.90 |
0.72 |
| Other ethnicity |
0.23 |
-0.91 |
1.38 |
0.58 |
0.69 |
| Key worker |
-0.03 |
-0.25 |
0.20 |
0.12 |
0.82 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.10 |
0.04 |
0.03 |
0.39 |
| 9688 |
0.01 |
0.01 |
11.18 |
1.82e-12 |
6 |
PHQ baseline, not controlling for prior symptoms
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.31 |
3.20 |
3.42 |
0.05 |
0.00e+00 |
| Anxiety disorders |
3.48 |
3.20 |
3.77 |
0.15 |
1.82e-122 |
| Eating disorders |
4.06 |
3.14 |
4.99 |
0.47 |
8.24e-18 |
| OCDs |
6.00 |
5.24 |
6.76 |
0.39 |
3.57e-54 |
| PTSD |
5.18 |
4.42 |
5.93 |
0.39 |
5.41e-41 |
| Depressive disorders |
7.19 |
7.05 |
7.33 |
0.07 |
0.00e+00 |
| Bipolar disorders |
9.75 |
9.39 |
10.12 |
0.19 |
0.00e+00 |
| 31315 |
0.26 |
0.26 |
1846.76 |
0.00e+00 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
3.56 |
3.46 |
3.66 |
0.05 |
0.00e+00 |
| Depressive and anxiety disorder |
6.64 |
6.49 |
6.79 |
0.08 |
0.00e+00 |
| Only depressive disorder |
3.53 |
3.33 |
3.73 |
0.10 |
7.11e-257 |
| Only anxiety disorder |
3.22 |
2.97 |
3.48 |
0.13 |
5.24e-133 |
| Eating disorders |
2.18 |
1.92 |
2.45 |
0.14 |
4.24e-57 |
| OCDs |
2.04 |
1.78 |
2.30 |
0.13 |
4.62e-54 |
| Psychotic and bipolar disorder |
0.27 |
-0.46 |
1.00 |
0.37 |
0.47 |
| Only psychotic disorder |
0.80 |
0.17 |
1.42 |
0.32 |
0.01 |
| Only bipolar disorder |
1.31 |
0.91 |
1.70 |
0.20 |
6.16e-11 |
| PTSD |
2.05 |
1.81 |
2.29 |
0.12 |
1.16e-63 |
| ASD |
2.80 |
2.34 |
3.27 |
0.24 |
4.82e-32 |
| ADHD |
1.90 |
1.28 |
2.51 |
0.31 |
1.73e-09 |
| Personality disorder |
3.40 |
3.06 |
3.74 |
0.17 |
6.36e-84 |
| 31315 |
0.26 |
0.26 |
1846.76 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.21 |
5.88 |
6.54 |
0.17 |
2.84e-294 |
| Anxiety disorders |
2.11 |
1.82 |
2.40 |
0.15 |
4.71e-45 |
| Eating disorders |
2.21 |
1.30 |
3.12 |
0.46 |
2.01e-06 |
| OCDs |
3.15 |
2.41 |
3.90 |
0.38 |
1.13e-16 |
| PTSD |
4.04 |
3.29 |
4.79 |
0.38 |
9.48e-26 |
| Depressive disorders |
5.91 |
5.76 |
6.07 |
0.08 |
0.00e+00 |
| Bipolar disorders |
8.33 |
7.97 |
8.69 |
0.18 |
0.00e+00 |
| Female |
0.92 |
0.76 |
1.08 |
0.08 |
4.69e-30 |
| Non-binary/Self-defined |
2.57 |
1.93 |
3.20 |
0.32 |
2.88e-15 |
| age_category_collapsed_reordered16-18 |
5.86 |
5.43 |
6.28 |
0.22 |
5.17e-160 |
| 19-25 years |
2.35 |
2.06 |
2.64 |
0.15 |
5.29e-56 |
| 36-45 years |
-0.77 |
-1.01 |
-0.52 |
0.12 |
6.56e-10 |
| 46-55 years |
-1.24 |
-1.47 |
-1.02 |
0.11 |
2.26e-27 |
| 56-65 years |
-2.42 |
-2.64 |
-2.19 |
0.11 |
3.89e-99 |
| 66-70 years |
-3.60 |
-3.89 |
-3.32 |
0.14 |
3.28e-135 |
| 71-75 years |
-3.75 |
-4.07 |
-3.42 |
0.17 |
6.47e-111 |
| 76+ years |
-3.60 |
-4.10 |
-3.10 |
0.25 |
2.18e-45 |
| Mixed or multiple ethnic origins |
0.38 |
-0.12 |
0.89 |
0.26 |
0.14 |
| Asian or Asian British |
-0.12 |
-0.74 |
0.49 |
0.31 |
0.70 |
| African or African British |
0.00 |
-1.05 |
1.05 |
0.53 |
1.00 |
| Other ethnicity |
1.14 |
0.21 |
2.08 |
0.48 |
0.02 |
| Time difference: Lockdown to baseline |
-0.21 |
-0.25 |
-0.18 |
0.02 |
9.53e-36 |
| 31315 |
0.26 |
0.26 |
1846.76 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.34 |
6.02 |
6.66 |
0.16 |
2.46e-321 |
| Depressive and anxiety disorder |
5.56 |
5.39 |
5.72 |
0.08 |
0.00e+00 |
| Only depressive disorder |
3.37 |
3.17 |
3.58 |
0.11 |
2.75e-220 |
| Only anxiety disorder |
2.04 |
1.78 |
2.31 |
0.13 |
1.74e-52 |
| Eating disorders |
1.56 |
1.29 |
1.82 |
0.13 |
4.43e-31 |
| OCDs |
1.44 |
1.19 |
1.69 |
0.13 |
6.49e-29 |
| Psychotic and bipolar disorder |
0.55 |
-0.16 |
1.26 |
0.36 |
0.13 |
| Only psychotic disorder |
0.87 |
0.26 |
1.48 |
0.31 |
0.005 |
| Only bipolar disorder |
1.48 |
1.10 |
1.86 |
0.20 |
3.66e-14 |
| PTSD |
2.08 |
1.84 |
2.31 |
0.12 |
1.95e-67 |
| ASD |
1.47 |
1.01 |
1.93 |
0.23 |
3.46e-10 |
| ADHD |
1.11 |
0.50 |
1.71 |
0.31 |
3.42e-04 |
| Personality disorder |
3.05 |
2.72 |
3.39 |
0.17 |
4.89e-71 |
| Female |
0.84 |
0.69 |
0.99 |
0.08 |
3.12e-27 |
| Non-binary/Self-defined |
1.38 |
0.77 |
1.99 |
0.31 |
9.79e-06 |
| age_category_collapsed_reordered16-18 |
5.95 |
5.55 |
6.35 |
0.20 |
1.42e-184 |
| 19-25 years |
2.16 |
1.88 |
2.44 |
0.14 |
7.55e-52 |
| 36-45 years |
-0.59 |
-0.82 |
-0.35 |
0.12 |
8.90e-07 |
| 46-55 years |
-0.84 |
-1.06 |
-0.62 |
0.11 |
4.21e-14 |
| 56-65 years |
-1.91 |
-2.13 |
-1.69 |
0.11 |
1.20e-65 |
| 66-70 years |
-3.15 |
-3.43 |
-2.87 |
0.14 |
4.83e-106 |
| 71-75 years |
-3.33 |
-3.65 |
-3.01 |
0.16 |
7.60e-91 |
| 76+ years |
-3.19 |
-3.67 |
-2.70 |
0.25 |
2.05e-38 |
| Mixed or multiple ethnic origins |
0.37 |
-0.11 |
0.86 |
0.25 |
0.13 |
| Asian or Asian British |
0.29 |
-0.29 |
0.87 |
0.30 |
0.33 |
| African or African British |
0.18 |
-0.82 |
1.18 |
0.51 |
0.72 |
| Other ethnicity |
0.80 |
-0.10 |
1.69 |
0.45 |
0.08 |
| Key worker |
-0.67 |
-0.81 |
-0.53 |
0.07 |
9.05e-21 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.25 |
-0.19 |
0.02 |
9.25e-42 |
| 31315 |
0.26 |
0.26 |
1846.76 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.34 |
2.00 |
2.69 |
0.18 |
1.27e-39 |
| Anxiety disorders |
2.02 |
1.68 |
2.37 |
0.18 |
1.40e-30 |
| Eating disorders |
2.44 |
1.38 |
3.49 |
0.54 |
6.42e-06 |
| OCDs |
3.94 |
3.02 |
4.86 |
0.47 |
3.70e-17 |
| PTSD |
4.00 |
3.00 |
5.00 |
0.51 |
3.81e-15 |
| Depressive disorders |
6.15 |
5.97 |
6.32 |
0.09 |
0.00e+00 |
| Bipolar disorders |
8.50 |
8.11 |
8.89 |
0.20 |
0.00e+00 |
| Female |
0.56 |
0.39 |
0.73 |
0.09 |
1.01e-10 |
| Non-binary/Self-defined |
2.17 |
1.48 |
2.85 |
0.35 |
5.84e-10 |
| Age |
-280.44 |
-293.04 |
-267.84 |
6.43 |
0.00e+00 |
| Age^2 |
31.51 |
20.12 |
42.89 |
5.81 |
5.88e-08 |
| Mixed or multiple ethnic origins |
0.44 |
-0.13 |
1.00 |
0.29 |
0.13 |
| Asian or Asian British |
0.04 |
-0.70 |
0.78 |
0.38 |
0.91 |
| African or African British |
-0.12 |
-1.29 |
1.06 |
0.60 |
0.84 |
| Other ethnicity |
1.48 |
0.42 |
2.54 |
0.54 |
0.006 |
| Time difference: Lockdown to baseline |
0.09 |
0.04 |
0.13 |
0.02 |
6.90e-05 |
| 24450 |
0.31 |
0.31 |
1872.46 |
0.00e+00 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.64 |
2.30 |
2.97 |
0.17 |
1.09e-52 |
| Depressive and anxiety disorder |
5.84 |
5.66 |
6.03 |
0.09 |
0.00e+00 |
| Only depressive disorder |
3.61 |
3.37 |
3.84 |
0.12 |
2.68e-196 |
| Only anxiety disorder |
2.14 |
1.83 |
2.45 |
0.16 |
6.67e-42 |
| Eating disorders |
1.79 |
1.51 |
2.08 |
0.15 |
1.61e-34 |
| OCDs |
1.46 |
1.18 |
1.74 |
0.14 |
3.17e-25 |
| Psychotic and bipolar disorder |
0.34 |
-0.47 |
1.14 |
0.41 |
0.42 |
| Only psychotic disorder |
0.83 |
0.17 |
1.49 |
0.34 |
0.01 |
| Only bipolar disorder |
1.48 |
1.08 |
1.88 |
0.20 |
5.23e-13 |
| PTSD |
2.05 |
1.80 |
2.31 |
0.13 |
2.48e-55 |
| ASD |
1.57 |
1.04 |
2.10 |
0.27 |
6.06e-09 |
| ADHD |
0.77 |
0.06 |
1.47 |
0.36 |
0.03 |
| Personality disorder |
2.85 |
2.49 |
3.21 |
0.18 |
1.47e-53 |
| Female |
0.43 |
0.27 |
0.59 |
0.08 |
2.32e-07 |
| Non-binary/Self-defined |
1.09 |
0.43 |
1.75 |
0.34 |
0.001 |
| Age |
-250.23 |
-262.89 |
-237.58 |
6.46 |
1.07e-317 |
| Age^2 |
14.63 |
3.35 |
25.91 |
5.75 |
0.01 |
| Mixed or multiple ethnic origins |
0.34 |
-0.20 |
0.88 |
0.27 |
0.22 |
| Asian or Asian British |
0.38 |
-0.32 |
1.09 |
0.36 |
0.28 |
| African or African British |
-0.02 |
-1.14 |
1.09 |
0.57 |
0.97 |
| Other ethnicity |
1.07 |
0.06 |
2.07 |
0.51 |
0.04 |
| Key worker |
-0.71 |
-0.86 |
-0.56 |
0.08 |
5.23e-20 |
| Time difference: Lockdown to baseline |
0.10 |
0.06 |
0.14 |
0.02 |
4.65e-06 |
| 24450 |
0.31 |
0.31 |
1872.46 |
0.00e+00 |
6 |
PHQ prepan
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
-1.65 |
-2.63 |
-0.67 |
0.50 |
9.81e-04 |
| Anxiety disorders |
1.89 |
0.81 |
2.97 |
0.55 |
5.93e-04 |
| Eating disorders |
0.02 |
-2.07 |
2.12 |
1.07 |
0.98 |
| OCDs |
1.82 |
0.36 |
3.29 |
0.75 |
0.01 |
| PTSD |
1.28 |
-0.43 |
2.99 |
0.87 |
0.14 |
| Depressive disorders |
1.19 |
0.20 |
2.17 |
0.50 |
0.02 |
| Bipolar disorders |
0.79 |
-0.27 |
1.85 |
0.54 |
0.15 |
| 11134 |
0.00 |
0.00 |
3.57 |
0.002 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
-1.55 |
-2.26 |
-0.84 |
0.36 |
1.69e-05 |
| Depressive and anxiety disorder |
1.08 |
0.36 |
1.79 |
0.37 |
0.003 |
| Only depressive disorder |
0.94 |
0.16 |
1.71 |
0.39 |
0.02 |
| Only anxiety disorder |
1.75 |
0.94 |
2.56 |
0.41 |
2.28e-05 |
| Eating disorders |
0.37 |
0.02 |
0.72 |
0.18 |
0.04 |
| OCDs |
0.01 |
-0.32 |
0.33 |
0.17 |
0.96 |
| Psychotic and bipolar disorder |
-0.79 |
-1.75 |
0.17 |
0.49 |
0.11 |
| Only psychotic disorder |
0.13 |
-0.66 |
0.92 |
0.40 |
0.75 |
| Only bipolar disorder |
-0.32 |
-0.80 |
0.15 |
0.24 |
0.18 |
| PTSD |
-0.17 |
-0.48 |
0.13 |
0.16 |
0.26 |
| ASD |
0.35 |
-0.28 |
0.98 |
0.32 |
0.28 |
| ADHD |
0.07 |
-0.79 |
0.93 |
0.44 |
0.87 |
| Personality disorder |
-0.02 |
-0.44 |
0.41 |
0.22 |
0.93 |
| 11134 |
0.00 |
0.00 |
3.57 |
0.002 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-2.11 |
-3.26 |
-0.97 |
0.58 |
2.90e-04 |
| Anxiety disorders |
1.82 |
0.74 |
2.90 |
0.55 |
9.92e-04 |
| Eating disorders |
-0.14 |
-2.24 |
1.96 |
1.07 |
0.90 |
| OCDs |
1.65 |
0.18 |
3.11 |
0.75 |
0.03 |
| PTSD |
1.03 |
-0.69 |
2.75 |
0.88 |
0.24 |
| Depressive disorders |
1.13 |
0.14 |
2.12 |
0.50 |
0.02 |
| Bipolar disorders |
0.79 |
-0.28 |
1.85 |
0.54 |
0.15 |
| Female |
0.29 |
0.00 |
0.58 |
0.15 |
0.05 |
| Non-binary/Self-defined |
-0.11 |
-0.93 |
0.72 |
0.42 |
0.80 |
| age_category_collapsed_reordered16-18 |
0.03 |
-0.66 |
0.72 |
0.35 |
0.93 |
| 19-25 years |
0.06 |
-0.32 |
0.44 |
0.19 |
0.75 |
| 36-45 years |
-0.04 |
-0.37 |
0.29 |
0.17 |
0.83 |
| 46-55 years |
-0.34 |
-0.66 |
-0.02 |
0.16 |
0.04 |
| 56-65 years |
-0.36 |
-0.72 |
0.00 |
0.18 |
0.05 |
| 66-70 years |
-0.31 |
-0.94 |
0.32 |
0.32 |
0.34 |
| 71-75 years |
-0.67 |
-1.51 |
0.17 |
0.43 |
0.12 |
| 76+ years |
0.19 |
-1.46 |
1.83 |
0.84 |
0.82 |
| Mixed or multiple ethnic origins |
-0.01 |
-0.76 |
0.74 |
0.38 |
0.97 |
| Asian or Asian British |
-1.33 |
-2.55 |
-0.11 |
0.62 |
0.03 |
| African or African British |
-1.12 |
-2.96 |
0.71 |
0.94 |
0.23 |
| Other ethnicity |
-0.05 |
-1.22 |
1.11 |
0.60 |
0.93 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.07 |
| 11134 |
0.00 |
0.00 |
3.57 |
0.002 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-2.15 |
-3.08 |
-1.21 |
0.48 |
6.66e-06 |
| Depressive and anxiety disorder |
1.09 |
0.37 |
1.81 |
0.37 |
0.003 |
| Only depressive disorder |
0.99 |
0.21 |
1.77 |
0.40 |
0.01 |
| Only anxiety disorder |
1.72 |
0.91 |
2.54 |
0.42 |
3.42e-05 |
| Eating disorders |
0.32 |
-0.03 |
0.67 |
0.18 |
0.07 |
| OCDs |
-0.02 |
-0.34 |
0.31 |
0.17 |
0.92 |
| Psychotic and bipolar disorder |
-0.69 |
-1.65 |
0.27 |
0.49 |
0.16 |
| Only psychotic disorder |
0.15 |
-0.65 |
0.94 |
0.41 |
0.72 |
| Only bipolar disorder |
-0.22 |
-0.70 |
0.25 |
0.24 |
0.36 |
| PTSD |
-0.17 |
-0.48 |
0.14 |
0.16 |
0.27 |
| ASD |
0.35 |
-0.29 |
0.99 |
0.33 |
0.29 |
| ADHD |
0.05 |
-0.81 |
0.91 |
0.44 |
0.91 |
| Personality disorder |
-0.05 |
-0.48 |
0.37 |
0.22 |
0.80 |
| Female |
0.26 |
-0.04 |
0.55 |
0.15 |
0.09 |
| Non-binary/Self-defined |
-0.11 |
-0.94 |
0.72 |
0.42 |
0.79 |
| age_category_collapsed_reordered16-18 |
0.05 |
-0.64 |
0.74 |
0.35 |
0.89 |
| 19-25 years |
0.04 |
-0.34 |
0.42 |
0.19 |
0.83 |
| 36-45 years |
-0.02 |
-0.35 |
0.31 |
0.17 |
0.92 |
| 46-55 years |
-0.32 |
-0.64 |
0.00 |
0.16 |
0.05 |
| 56-65 years |
-0.33 |
-0.69 |
0.04 |
0.19 |
0.08 |
| 66-70 years |
-0.20 |
-0.84 |
0.44 |
0.32 |
0.54 |
| 71-75 years |
-0.53 |
-1.38 |
0.32 |
0.43 |
0.22 |
| 76+ years |
0.29 |
-1.36 |
1.94 |
0.84 |
0.73 |
| Mixed or multiple ethnic origins |
0.02 |
-0.73 |
0.77 |
0.38 |
0.96 |
| Asian or Asian British |
-1.19 |
-2.41 |
0.03 |
0.62 |
0.06 |
| African or African British |
-1.09 |
-2.93 |
0.75 |
0.94 |
0.25 |
| Other ethnicity |
-0.27 |
-1.43 |
0.89 |
0.59 |
0.64 |
| Key worker |
0.12 |
-0.10 |
0.35 |
0.12 |
0.29 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.06 |
| 11134 |
0.00 |
0.00 |
3.57 |
0.002 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-2.27 |
-3.39 |
-1.15 |
0.57 |
7.10e-05 |
| Anxiety disorders |
1.83 |
0.75 |
2.91 |
0.55 |
9.15e-04 |
| Eating disorders |
-0.12 |
-2.22 |
1.98 |
1.07 |
0.91 |
| OCDs |
1.66 |
0.19 |
3.12 |
0.75 |
0.03 |
| PTSD |
1.07 |
-0.65 |
2.79 |
0.88 |
0.22 |
| Depressive disorders |
1.15 |
0.16 |
2.14 |
0.50 |
0.02 |
| Bipolar disorders |
0.81 |
-0.25 |
1.87 |
0.54 |
0.14 |
| Female |
0.29 |
0.00 |
0.58 |
0.15 |
0.05 |
| Non-binary/Self-defined |
-0.12 |
-0.94 |
0.71 |
0.42 |
0.78 |
| Age |
-17.75 |
-29.42 |
-6.08 |
5.95 |
0.003 |
| Age^2 |
-0.08 |
-11.51 |
11.35 |
5.83 |
0.99 |
| Mixed or multiple ethnic origins |
-0.01 |
-0.77 |
0.74 |
0.38 |
0.97 |
| Asian or Asian British |
-1.33 |
-2.55 |
-0.11 |
0.62 |
0.03 |
| African or African British |
-1.13 |
-2.97 |
0.70 |
0.94 |
0.23 |
| Other ethnicity |
-0.05 |
-1.22 |
1.12 |
0.60 |
0.93 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.07 |
| 11134 |
0.00 |
0.00 |
3.57 |
0.002 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-2.28 |
-3.18 |
-1.38 |
0.46 |
7.32e-07 |
| Depressive and anxiety disorder |
1.11 |
0.38 |
1.83 |
0.37 |
0.003 |
| Only depressive disorder |
1.01 |
0.23 |
1.78 |
0.40 |
0.01 |
| Only anxiety disorder |
1.73 |
0.92 |
2.55 |
0.42 |
3.12e-05 |
| Eating disorders |
0.32 |
-0.03 |
0.67 |
0.18 |
0.07 |
| OCDs |
-0.02 |
-0.34 |
0.31 |
0.17 |
0.92 |
| Psychotic and bipolar disorder |
-0.69 |
-1.66 |
0.27 |
0.49 |
0.16 |
| Only psychotic disorder |
0.16 |
-0.63 |
0.96 |
0.41 |
0.69 |
| Only bipolar disorder |
-0.22 |
-0.69 |
0.26 |
0.24 |
0.37 |
| PTSD |
-0.18 |
-0.48 |
0.13 |
0.16 |
0.26 |
| ASD |
0.34 |
-0.30 |
0.98 |
0.33 |
0.30 |
| ADHD |
0.06 |
-0.80 |
0.92 |
0.44 |
0.89 |
| Personality disorder |
-0.06 |
-0.49 |
0.37 |
0.22 |
0.79 |
| Female |
0.25 |
-0.04 |
0.54 |
0.15 |
0.09 |
| Non-binary/Self-defined |
-0.12 |
-0.95 |
0.71 |
0.42 |
0.77 |
| Age |
-15.24 |
-27.15 |
-3.33 |
6.08 |
0.01 |
| Age^2 |
0.65 |
-11.14 |
12.45 |
6.02 |
0.91 |
| Mixed or multiple ethnic origins |
0.02 |
-0.74 |
0.77 |
0.38 |
0.96 |
| Asian or Asian British |
-1.19 |
-2.41 |
0.03 |
0.62 |
0.06 |
| African or African British |
-1.10 |
-2.94 |
0.73 |
0.94 |
0.24 |
| Other ethnicity |
-0.27 |
-1.43 |
0.89 |
0.59 |
0.65 |
| Key worker |
0.12 |
-0.11 |
0.34 |
0.12 |
0.31 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.06 |
| 11134 |
0.00 |
0.00 |
3.57 |
0.002 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.15 |
1.27 |
3.04 |
0.45 |
1.76e-06 |
| phq.sum_score_prepan |
0.61 |
0.60 |
0.63 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.84 |
-0.13 |
1.80 |
0.49 |
0.09 |
| Eating disorders |
0.25 |
-1.62 |
2.12 |
0.95 |
0.79 |
| OCDs |
1.91 |
0.61 |
3.21 |
0.66 |
0.004 |
| PTSD |
1.14 |
-0.38 |
2.66 |
0.78 |
0.14 |
| Depressive disorders |
1.83 |
0.95 |
2.71 |
0.45 |
4.61e-05 |
| Bipolar disorders |
2.21 |
1.26 |
3.16 |
0.48 |
4.76e-06 |
| 11134 |
0.41 |
0.41 |
1107.68 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.76 |
2.12 |
3.40 |
0.33 |
3.18e-17 |
| phq.sum_score_prepan |
0.59 |
0.57 |
0.60 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.18 |
0.55 |
1.81 |
0.32 |
2.47e-04 |
| Only depressive disorder |
0.52 |
-0.16 |
1.20 |
0.35 |
0.13 |
| Only anxiety disorder |
0.40 |
-0.32 |
1.11 |
0.37 |
0.28 |
| Eating disorders |
1.02 |
0.72 |
1.33 |
0.16 |
6.68e-11 |
| OCDs |
0.68 |
0.39 |
0.96 |
0.15 |
4.12e-06 |
| Psychotic and bipolar disorder |
-0.69 |
-1.53 |
0.16 |
0.43 |
0.11 |
| Only psychotic disorder |
0.19 |
-0.50 |
0.89 |
0.36 |
0.58 |
| Only bipolar disorder |
0.15 |
-0.27 |
0.56 |
0.21 |
0.49 |
| PTSD |
0.58 |
0.31 |
0.85 |
0.14 |
2.86e-05 |
| ASD |
1.04 |
0.48 |
1.59 |
0.28 |
2.62e-04 |
| ADHD |
0.46 |
-0.30 |
1.22 |
0.39 |
0.23 |
| Personality disorder |
1.28 |
0.90 |
1.66 |
0.19 |
3.03e-11 |
| 11162 |
0.02 |
0.02 |
44.52 |
4.15e-54 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.13 |
1.09 |
3.16 |
0.53 |
5.46e-05 |
| phq.sum_score_prepan |
0.58 |
0.57 |
0.60 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.74 |
-0.22 |
1.70 |
0.49 |
0.13 |
| Eating disorders |
0.16 |
-1.69 |
2.02 |
0.95 |
0.86 |
| OCDs |
1.60 |
0.31 |
2.90 |
0.66 |
0.02 |
| PTSD |
1.26 |
-0.26 |
2.78 |
0.78 |
0.10 |
| Depressive disorders |
2.01 |
1.13 |
2.89 |
0.45 |
7.48e-06 |
| Bipolar disorders |
2.51 |
1.56 |
3.46 |
0.48 |
2.07e-07 |
| Female |
0.29 |
0.03 |
0.54 |
0.13 |
0.03 |
| Non-binary/Self-defined |
0.69 |
-0.04 |
1.42 |
0.37 |
0.06 |
| age_category_collapsed_reordered16-18 |
1.75 |
1.14 |
2.37 |
0.32 |
2.79e-08 |
| 19-25 years |
0.83 |
0.49 |
1.16 |
0.17 |
1.39e-06 |
| 36-45 years |
-0.22 |
-0.51 |
0.08 |
0.15 |
0.15 |
| 46-55 years |
-0.44 |
-0.73 |
-0.16 |
0.14 |
0.002 |
| 56-65 years |
-1.04 |
-1.36 |
-0.72 |
0.16 |
2.25e-10 |
| 66-70 years |
-2.05 |
-2.62 |
-1.49 |
0.29 |
9.97e-13 |
| 71-75 years |
-2.59 |
-3.34 |
-1.84 |
0.38 |
1.46e-11 |
| 76+ years |
-1.93 |
-3.39 |
-0.48 |
0.74 |
0.009 |
| Mixed or multiple ethnic origins |
0.10 |
-0.56 |
0.77 |
0.34 |
0.76 |
| Asian or Asian British |
-0.91 |
-1.99 |
0.17 |
0.55 |
0.10 |
| African or African British |
-0.47 |
-2.09 |
1.15 |
0.83 |
0.57 |
| Other ethnicity |
0.32 |
-0.72 |
1.36 |
0.53 |
0.55 |
| Key worker |
-0.55 |
-0.75 |
-0.35 |
0.10 |
6.75e-08 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.12 |
0.03 |
0.04 |
| 11162 |
0.02 |
0.02 |
44.52 |
4.15e-54 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.70 |
1.87 |
3.53 |
0.42 |
2.12e-10 |
| phq.sum_score_prepan |
0.56 |
0.55 |
0.58 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.35 |
0.72 |
1.98 |
0.32 |
2.87e-05 |
| Only depressive disorder |
0.90 |
0.22 |
1.58 |
0.35 |
0.010 |
| Only anxiety disorder |
0.30 |
-0.41 |
1.02 |
0.36 |
0.40 |
| Eating disorders |
0.92 |
0.62 |
1.23 |
0.16 |
3.80e-09 |
| OCDs |
0.57 |
0.28 |
0.86 |
0.15 |
9.41e-05 |
| Psychotic and bipolar disorder |
-0.50 |
-1.34 |
0.34 |
0.43 |
0.24 |
| Only psychotic disorder |
0.24 |
-0.45 |
0.94 |
0.35 |
0.50 |
| Only bipolar disorder |
0.31 |
-0.10 |
0.73 |
0.21 |
0.14 |
| PTSD |
0.66 |
0.39 |
0.93 |
0.14 |
1.94e-06 |
| ASD |
0.68 |
0.12 |
1.24 |
0.29 |
0.02 |
| ADHD |
0.32 |
-0.43 |
1.08 |
0.39 |
0.40 |
| Personality disorder |
1.19 |
0.82 |
1.57 |
0.19 |
5.78e-10 |
| Female |
0.12 |
-0.14 |
0.37 |
0.13 |
0.38 |
| Non-binary/Self-defined |
0.28 |
-0.44 |
1.01 |
0.37 |
0.44 |
| age_category_collapsed_reordered16-18 |
1.89 |
1.28 |
2.50 |
0.31 |
1.06e-09 |
| 19-25 years |
0.83 |
0.50 |
1.16 |
0.17 |
8.77e-07 |
| 36-45 years |
-0.18 |
-0.47 |
0.11 |
0.15 |
0.23 |
| 46-55 years |
-0.35 |
-0.63 |
-0.07 |
0.14 |
0.02 |
| 56-65 years |
-0.90 |
-1.22 |
-0.58 |
0.16 |
4.16e-08 |
| 66-70 years |
-1.80 |
-2.36 |
-1.24 |
0.29 |
2.78e-10 |
| 71-75 years |
-2.29 |
-3.04 |
-1.55 |
0.38 |
1.66e-09 |
| 76+ years |
-1.68 |
-3.12 |
-0.23 |
0.74 |
0.02 |
| Mixed or multiple ethnic origins |
0.07 |
-0.58 |
0.73 |
0.34 |
0.83 |
| Asian or Asian British |
-0.67 |
-1.74 |
0.39 |
0.54 |
0.21 |
| African or African British |
-0.31 |
-1.92 |
1.29 |
0.82 |
0.70 |
| Other ethnicity |
0.13 |
-0.88 |
1.15 |
0.52 |
0.79 |
| Key worker |
-0.45 |
-0.65 |
-0.25 |
0.10 |
8.99e-06 |
| Time difference: Lockdown to baseline |
0.07 |
0.01 |
0.13 |
0.03 |
0.02 |
| 11162 |
0.02 |
0.02 |
44.52 |
4.15e-54 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.87 |
0.86 |
2.88 |
0.52 |
3.01e-04 |
| phq.sum_score_prepan |
0.59 |
0.57 |
0.60 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.73 |
-0.23 |
1.69 |
0.49 |
0.13 |
| Eating disorders |
0.12 |
-1.73 |
1.98 |
0.95 |
0.90 |
| OCDs |
1.64 |
0.34 |
2.93 |
0.66 |
0.01 |
| PTSD |
1.21 |
-0.31 |
2.73 |
0.78 |
0.12 |
| Depressive disorders |
1.96 |
1.08 |
2.84 |
0.45 |
1.25e-05 |
| Bipolar disorders |
2.45 |
1.51 |
3.40 |
0.48 |
3.81e-07 |
| Female |
0.26 |
0.01 |
0.52 |
0.13 |
0.04 |
| Non-binary/Self-defined |
0.66 |
-0.07 |
1.39 |
0.37 |
0.07 |
| Age |
-77.24 |
-87.78 |
-66.69 |
5.38 |
2.46e-46 |
| Age^2 |
-3.49 |
-13.89 |
6.91 |
5.31 |
0.51 |
| Mixed or multiple ethnic origins |
0.08 |
-0.58 |
0.75 |
0.34 |
0.80 |
| Asian or Asian British |
-0.88 |
-1.96 |
0.20 |
0.55 |
0.11 |
| African or African British |
-0.45 |
-2.07 |
1.17 |
0.83 |
0.59 |
| Other ethnicity |
0.31 |
-0.73 |
1.34 |
0.53 |
0.56 |
| Key worker |
-0.55 |
-0.75 |
-0.35 |
0.10 |
5.63e-08 |
| Time difference: Lockdown to baseline |
0.07 |
0.01 |
0.12 |
0.03 |
0.03 |
| 11162 |
0.02 |
0.02 |
44.52 |
4.15e-54 |
6 |
Model 2b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.53 |
1.73 |
3.34 |
0.41 |
7.05e-10 |
| phq.sum_score_prepan |
0.57 |
0.55 |
0.58 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.26 |
0.63 |
1.89 |
0.32 |
8.78e-05 |
| Only depressive disorder |
0.85 |
0.16 |
1.53 |
0.35 |
0.02 |
| Only anxiety disorder |
0.26 |
-0.45 |
0.98 |
0.36 |
0.47 |
| Eating disorders |
0.93 |
0.62 |
1.24 |
0.16 |
2.98e-09 |
| OCDs |
0.56 |
0.28 |
0.85 |
0.15 |
1.15e-04 |
| Psychotic and bipolar disorder |
-0.47 |
-1.31 |
0.37 |
0.43 |
0.28 |
| Only psychotic disorder |
0.27 |
-0.42 |
0.97 |
0.35 |
0.44 |
| Only bipolar disorder |
0.31 |
-0.11 |
0.73 |
0.21 |
0.14 |
| PTSD |
0.67 |
0.40 |
0.94 |
0.14 |
1.31e-06 |
| ASD |
0.74 |
0.18 |
1.30 |
0.29 |
0.009 |
| ADHD |
0.28 |
-0.47 |
1.04 |
0.39 |
0.46 |
| Personality disorder |
1.12 |
0.74 |
1.49 |
0.19 |
6.66e-09 |
| Female |
0.10 |
-0.16 |
0.35 |
0.13 |
0.46 |
| Non-binary/Self-defined |
0.26 |
-0.47 |
0.98 |
0.37 |
0.48 |
| Age |
-71.08 |
-81.67 |
-60.49 |
5.40 |
3.03e-39 |
| Age^2 |
-0.13 |
-10.45 |
10.20 |
5.27 |
0.98 |
| Mixed or multiple ethnic origins |
0.05 |
-0.60 |
0.71 |
0.34 |
0.87 |
| Asian or Asian British |
-0.66 |
-1.73 |
0.40 |
0.54 |
0.22 |
| African or African British |
-0.30 |
-1.91 |
1.31 |
0.82 |
0.71 |
| Other ethnicity |
0.12 |
-0.89 |
1.13 |
0.52 |
0.82 |
| Key worker |
-0.46 |
-0.65 |
-0.26 |
0.10 |
6.82e-06 |
| Time difference: Lockdown to baseline |
0.07 |
0.01 |
0.13 |
0.03 |
0.02 |
| 11162 |
0.02 |
0.02 |
44.52 |
4.15e-54 |
6 |
PHQ prepan: sensitivity
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline #### Subset of participants 3 months prior to pandemic
| Intercept |
2.20 |
-0.23 |
4.63 |
1.24 |
0.08 |
| phq.sum_score_prepan |
0.64 |
0.59 |
0.69 |
0.03 |
1.62e-99 |
| Depressive and anxiety disorder |
0.09 |
-1.58 |
1.76 |
0.85 |
0.92 |
| Only depressive disorder |
-0.11 |
-1.91 |
1.69 |
0.92 |
0.91 |
| Only anxiety disorder |
-0.15 |
-2.15 |
1.85 |
1.02 |
0.88 |
| Eating disorders |
1.14 |
0.09 |
2.20 |
0.54 |
0.03 |
| OCDs |
0.04 |
-1.02 |
1.11 |
0.54 |
0.94 |
| Psychotic and bipolar disorder |
-0.82 |
-3.46 |
1.83 |
1.35 |
0.55 |
| Only psychotic disorder |
-0.84 |
-3.47 |
1.78 |
1.34 |
0.53 |
| Only bipolar disorder |
-0.13 |
-1.80 |
1.53 |
0.85 |
0.88 |
| PTSD |
1.41 |
0.43 |
2.39 |
0.50 |
0.005 |
| ASD |
2.51 |
0.66 |
4.37 |
0.94 |
0.008 |
| ADHD |
-1.75 |
-4.34 |
0.83 |
1.32 |
0.18 |
| Personality disorder |
0.46 |
-0.87 |
1.79 |
0.68 |
0.49 |
| Female |
0.41 |
-0.46 |
1.28 |
0.44 |
0.35 |
| Non-binary/Self-defined |
0.17 |
-3.00 |
3.33 |
1.61 |
0.92 |
| age_category_collapsed_reordered16-18 |
1.56 |
-0.35 |
3.47 |
0.97 |
0.11 |
| 19-25 years |
0.28 |
-1.00 |
1.56 |
0.65 |
0.67 |
| 36-45 years |
0.24 |
-0.83 |
1.31 |
0.55 |
0.66 |
| 46-55 years |
-0.75 |
-1.82 |
0.32 |
0.55 |
0.17 |
| 56-65 years |
-0.06 |
-1.19 |
1.06 |
0.57 |
0.91 |
| 66-70 years |
-0.89 |
-2.89 |
1.11 |
1.02 |
0.38 |
| 71-75 years |
-2.96 |
-5.81 |
-0.11 |
1.45 |
0.04 |
| 76+ years |
1.21 |
-2.30 |
4.72 |
1.79 |
0.50 |
| Mixed or multiple ethnic origins |
-1.60 |
-3.90 |
0.70 |
1.17 |
0.17 |
| Asian or Asian British |
-0.15 |
-3.81 |
3.51 |
1.86 |
0.94 |
| African or African British |
-2.48 |
-6.81 |
1.85 |
2.21 |
0.26 |
| Other ethnicity |
-2.58 |
-6.87 |
1.71 |
2.19 |
0.24 |
| Key worker |
-0.18 |
-0.91 |
0.56 |
0.37 |
0.64 |
| Time difference: Lockdown to baseline |
0.06 |
-0.12 |
0.23 |
0.09 |
0.52 |
| 827 |
0.02 |
0.01 |
2.97 |
0.007 |
6 |
Subset of participants 6 months prior to pandemic
| Intercept |
1.94 |
0.22 |
3.66 |
0.88 |
0.03 |
| phq.sum_score_prepan |
0.62 |
0.59 |
0.66 |
0.02 |
1.08e-190 |
| Depressive and anxiety disorder |
0.57 |
-0.55 |
1.68 |
0.57 |
0.32 |
| Only depressive disorder |
0.29 |
-0.93 |
1.52 |
0.62 |
0.64 |
| Only anxiety disorder |
-0.13 |
-1.47 |
1.21 |
0.69 |
0.85 |
| Eating disorders |
1.35 |
0.58 |
2.13 |
0.39 |
5.91e-04 |
| OCDs |
0.40 |
-0.33 |
1.12 |
0.37 |
0.28 |
| Psychotic and bipolar disorder |
-1.39 |
-3.53 |
0.75 |
1.09 |
0.20 |
| Only psychotic disorder |
-0.05 |
-1.65 |
1.55 |
0.81 |
0.95 |
| Only bipolar disorder |
-0.02 |
-1.11 |
1.07 |
0.55 |
0.97 |
| PTSD |
1.33 |
0.64 |
2.03 |
0.35 |
1.59e-04 |
| ASD |
1.25 |
-0.15 |
2.65 |
0.72 |
0.08 |
| ADHD |
-1.00 |
-2.66 |
0.65 |
0.84 |
0.24 |
| Personality disorder |
1.35 |
0.40 |
2.29 |
0.48 |
0.005 |
| Female |
0.30 |
-0.32 |
0.92 |
0.32 |
0.34 |
| Non-binary/Self-defined |
0.53 |
-1.45 |
2.50 |
1.01 |
0.60 |
| age_category_collapsed_reordered16-18 |
1.98 |
0.79 |
3.17 |
0.61 |
0.001 |
| 19-25 years |
0.29 |
-0.61 |
1.20 |
0.46 |
0.53 |
| 36-45 years |
-0.38 |
-1.15 |
0.39 |
0.39 |
0.33 |
| 46-55 years |
-0.82 |
-1.58 |
-0.05 |
0.39 |
0.04 |
| 56-65 years |
-0.47 |
-1.29 |
0.34 |
0.41 |
0.25 |
| 66-70 years |
-1.28 |
-2.66 |
0.09 |
0.70 |
0.07 |
| 71-75 years |
-2.98 |
-4.65 |
-1.31 |
0.85 |
4.65e-04 |
| 76+ years |
-0.07 |
-2.60 |
2.45 |
1.29 |
0.95 |
| Mixed or multiple ethnic origins |
-0.84 |
-2.44 |
0.76 |
0.82 |
0.30 |
| Asian or Asian British |
-1.05 |
-3.18 |
1.07 |
1.09 |
0.33 |
| African or African British |
-1.68 |
-5.27 |
1.91 |
1.83 |
0.36 |
| Other ethnicity |
-1.30 |
-3.92 |
1.33 |
1.34 |
0.33 |
| Key worker |
-0.23 |
-0.74 |
0.27 |
0.26 |
0.37 |
| Time difference: Lockdown to baseline |
0.09 |
-0.04 |
0.23 |
0.07 |
0.19 |
| 1633 |
0.02 |
0.02 |
5.49 |
1.22e-05 |
6 |
Subset of participants 9 months prior to pandemic
| Intercept |
3.03 |
1.62 |
4.43 |
0.72 |
2.51e-05 |
| phq.sum_score_prepan |
0.60 |
0.57 |
0.63 |
0.01 |
6.22e-281 |
| Depressive and anxiety disorder |
0.78 |
-0.13 |
1.70 |
0.47 |
0.09 |
| Only depressive disorder |
0.52 |
-0.47 |
1.51 |
0.51 |
0.30 |
| Only anxiety disorder |
-0.29 |
-1.40 |
0.82 |
0.57 |
0.60 |
| Eating disorders |
1.40 |
0.78 |
2.02 |
0.32 |
9.53e-06 |
| OCDs |
0.38 |
-0.20 |
0.96 |
0.30 |
0.20 |
| Psychotic and bipolar disorder |
-0.75 |
-2.36 |
0.87 |
0.82 |
0.36 |
| Only psychotic disorder |
0.55 |
-0.74 |
1.85 |
0.66 |
0.40 |
| Only bipolar disorder |
0.40 |
-0.46 |
1.27 |
0.44 |
0.36 |
| PTSD |
1.17 |
0.63 |
1.72 |
0.28 |
2.52e-05 |
| ASD |
0.79 |
-0.34 |
1.93 |
0.58 |
0.17 |
| ADHD |
-0.86 |
-2.27 |
0.54 |
0.72 |
0.23 |
| Personality disorder |
1.35 |
0.60 |
2.10 |
0.38 |
4.21e-04 |
| Female |
-0.08 |
-0.56 |
0.41 |
0.25 |
0.76 |
| Non-binary/Self-defined |
0.11 |
-1.40 |
1.63 |
0.77 |
0.89 |
| age_category_collapsed_reordered16-18 |
2.11 |
1.04 |
3.17 |
0.54 |
1.11e-04 |
| 19-25 years |
0.37 |
-0.37 |
1.11 |
0.38 |
0.33 |
| 36-45 years |
-0.19 |
-0.80 |
0.42 |
0.31 |
0.54 |
| 46-55 years |
-0.43 |
-1.02 |
0.16 |
0.30 |
0.15 |
| 56-65 years |
-0.69 |
-1.32 |
-0.05 |
0.33 |
0.04 |
| 66-70 years |
-1.07 |
-2.11 |
-0.02 |
0.53 |
0.05 |
| 71-75 years |
-2.31 |
-3.60 |
-1.02 |
0.66 |
4.63e-04 |
| 76+ years |
-0.53 |
-2.71 |
1.65 |
1.11 |
0.63 |
| Mixed or multiple ethnic origins |
0.01 |
-1.39 |
1.42 |
0.72 |
0.99 |
| Asian or Asian British |
-1.04 |
-2.77 |
0.69 |
0.88 |
0.24 |
| African or African British |
0.51 |
-2.30 |
3.32 |
1.43 |
0.72 |
| Other ethnicity |
-1.53 |
-3.34 |
0.29 |
0.92 |
0.10 |
| Key worker |
-0.37 |
-0.78 |
0.03 |
0.21 |
0.07 |
| Time difference: Lockdown to baseline |
0.00 |
-0.11 |
0.12 |
0.06 |
0.94 |
| 2709 |
0.03 |
0.03 |
13.19 |
9.03e-15 |
6 |
PHQ retro
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.04 |
2.90 |
3.18 |
0.07 |
0.00e+00 |
| Anxiety disorders |
0.61 |
0.28 |
0.93 |
0.17 |
2.45e-04 |
| Eating disorders |
0.57 |
-0.40 |
1.54 |
0.50 |
0.25 |
| OCDs |
1.07 |
0.29 |
1.85 |
0.40 |
0.007 |
| PTSD |
1.06 |
0.26 |
1.86 |
0.41 |
0.010 |
| Depressive disorders |
0.92 |
0.74 |
1.09 |
0.09 |
1.60e-25 |
| Bipolar disorders |
0.89 |
0.50 |
1.27 |
0.20 |
7.07e-06 |
| 19512 |
0.01 |
0.01 |
18.92 |
4.40e-22 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
3.08 |
2.95 |
3.22 |
0.07 |
0.00e+00 |
| Depressive and anxiety disorder |
0.74 |
0.56 |
0.92 |
0.09 |
1.08e-15 |
| Only depressive disorder |
0.41 |
0.17 |
0.65 |
0.12 |
8.67e-04 |
| Only anxiety disorder |
0.59 |
0.29 |
0.88 |
0.15 |
9.74e-05 |
| Eating disorders |
0.66 |
0.37 |
0.94 |
0.14 |
5.62e-06 |
| OCDs |
0.19 |
-0.08 |
0.47 |
0.14 |
0.16 |
| Psychotic and bipolar disorder |
-0.92 |
-1.71 |
-0.14 |
0.40 |
0.02 |
| Only psychotic disorder |
-0.55 |
-1.23 |
0.13 |
0.35 |
0.11 |
| Only bipolar disorder |
-0.09 |
-0.51 |
0.34 |
0.22 |
0.69 |
| PTSD |
0.56 |
0.30 |
0.81 |
0.13 |
1.57e-05 |
| ASD |
0.51 |
0.02 |
1.00 |
0.25 |
0.04 |
| ADHD |
0.08 |
-0.57 |
0.73 |
0.33 |
0.80 |
| Personality disorder |
0.29 |
-0.07 |
0.65 |
0.18 |
0.11 |
| 19512 |
0.01 |
0.01 |
18.92 |
4.40e-22 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.47 |
4.09 |
4.84 |
0.19 |
1.67e-119 |
| Anxiety disorders |
0.24 |
-0.11 |
0.58 |
0.17 |
0.18 |
| Eating disorders |
0.03 |
-0.97 |
1.04 |
0.51 |
0.95 |
| OCDs |
0.35 |
-0.46 |
1.15 |
0.41 |
0.40 |
| PTSD |
0.75 |
-0.09 |
1.58 |
0.43 |
0.08 |
| Depressive disorders |
0.69 |
0.50 |
0.88 |
0.10 |
1.63e-12 |
| Bipolar disorders |
0.70 |
0.30 |
1.10 |
0.20 |
6.20e-04 |
| Female |
0.75 |
0.55 |
0.95 |
0.10 |
2.56e-13 |
| Non-binary/Self-defined |
0.16 |
-0.52 |
0.84 |
0.35 |
0.64 |
| age_category_collapsed_reordered16-18 |
1.41 |
0.98 |
1.84 |
0.22 |
1.45e-10 |
| 19-25 years |
0.82 |
0.52 |
1.12 |
0.15 |
7.67e-08 |
| 36-45 years |
-0.41 |
-0.68 |
-0.15 |
0.13 |
0.002 |
| 46-55 years |
-0.43 |
-0.68 |
-0.18 |
0.13 |
6.63e-04 |
| 56-65 years |
-0.58 |
-0.83 |
-0.33 |
0.13 |
5.95e-06 |
| 66-70 years |
-0.95 |
-1.31 |
-0.59 |
0.19 |
3.03e-07 |
| 71-75 years |
-1.05 |
-1.50 |
-0.60 |
0.23 |
5.38e-06 |
| 76+ years |
-1.28 |
-2.05 |
-0.51 |
0.39 |
0.001 |
| Mixed or multiple ethnic origins |
-0.21 |
-0.77 |
0.34 |
0.28 |
0.45 |
| Asian or Asian British |
-0.19 |
-0.90 |
0.52 |
0.36 |
0.60 |
| African or African British |
-0.28 |
-1.46 |
0.91 |
0.60 |
0.65 |
| Other ethnicity |
-0.40 |
-1.39 |
0.58 |
0.50 |
0.42 |
| Time difference: Lockdown to baseline |
-0.24 |
-0.27 |
-0.20 |
0.02 |
9.59e-36 |
| 19512 |
0.01 |
0.01 |
18.92 |
4.40e-22 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.35 |
3.98 |
4.73 |
0.19 |
9.70e-113 |
| Depressive and anxiety disorder |
0.59 |
0.39 |
0.79 |
0.10 |
8.12e-09 |
| Only depressive disorder |
0.45 |
0.20 |
0.71 |
0.13 |
5.25e-04 |
| Only anxiety disorder |
0.26 |
-0.05 |
0.57 |
0.16 |
0.11 |
| Eating disorders |
0.43 |
0.15 |
0.72 |
0.15 |
0.003 |
| OCDs |
0.04 |
-0.23 |
0.32 |
0.14 |
0.76 |
| Psychotic and bipolar disorder |
-0.69 |
-1.48 |
0.10 |
0.40 |
0.09 |
| Only psychotic disorder |
-0.42 |
-1.11 |
0.27 |
0.35 |
0.23 |
| Only bipolar disorder |
0.05 |
-0.38 |
0.48 |
0.22 |
0.83 |
| PTSD |
0.57 |
0.31 |
0.83 |
0.13 |
1.50e-05 |
| ASD |
0.20 |
-0.30 |
0.70 |
0.26 |
0.44 |
| ADHD |
0.00 |
-0.66 |
0.67 |
0.34 |
1.00 |
| Personality disorder |
0.26 |
-0.11 |
0.63 |
0.19 |
0.17 |
| Female |
0.68 |
0.48 |
0.88 |
0.10 |
2.01e-11 |
| Non-binary/Self-defined |
0.03 |
-0.64 |
0.71 |
0.34 |
0.92 |
| age_category_collapsed_reordered16-18 |
1.60 |
1.17 |
2.02 |
0.22 |
1.35e-13 |
| 19-25 years |
0.85 |
0.55 |
1.14 |
0.15 |
2.28e-08 |
| 36-45 years |
-0.41 |
-0.68 |
-0.15 |
0.13 |
0.002 |
| 46-55 years |
-0.41 |
-0.66 |
-0.17 |
0.13 |
0.001 |
| 56-65 years |
-0.49 |
-0.75 |
-0.24 |
0.13 |
1.49e-04 |
| 66-70 years |
-0.73 |
-1.10 |
-0.36 |
0.19 |
1.11e-04 |
| 71-75 years |
-0.87 |
-1.33 |
-0.42 |
0.23 |
1.72e-04 |
| 76+ years |
-1.12 |
-1.88 |
-0.36 |
0.39 |
0.004 |
| Mixed or multiple ethnic origins |
-0.11 |
-0.66 |
0.44 |
0.28 |
0.70 |
| Asian or Asian British |
0.00 |
-0.69 |
0.69 |
0.35 |
1.00 |
| African or African British |
-0.20 |
-1.36 |
0.96 |
0.59 |
0.73 |
| Other ethnicity |
-0.53 |
-1.49 |
0.44 |
0.49 |
0.28 |
| Key worker |
0.26 |
0.09 |
0.42 |
0.08 |
0.002 |
| Time difference: Lockdown to baseline |
-0.24 |
-0.27 |
-0.20 |
0.02 |
1.00e-36 |
| 19512 |
0.01 |
0.01 |
18.92 |
4.40e-22 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.70 |
2.28 |
3.13 |
0.22 |
2.00e-35 |
| Anxiety disorders |
0.27 |
-0.15 |
0.69 |
0.21 |
0.21 |
| Eating disorders |
0.19 |
-1.03 |
1.41 |
0.62 |
0.76 |
| OCDs |
0.17 |
-0.84 |
1.18 |
0.51 |
0.74 |
| PTSD |
0.93 |
-0.26 |
2.11 |
0.60 |
0.12 |
| Depressive disorders |
0.94 |
0.71 |
1.17 |
0.12 |
1.12e-15 |
| Bipolar disorders |
0.94 |
0.49 |
1.38 |
0.23 |
3.45e-05 |
| Female |
0.51 |
0.29 |
0.73 |
0.11 |
6.00e-06 |
| Non-binary/Self-defined |
-0.56 |
-1.30 |
0.18 |
0.38 |
0.14 |
| Age |
-77.73 |
-89.91 |
-65.54 |
6.22 |
1.14e-35 |
| Age^2 |
7.11 |
-4.48 |
18.71 |
5.92 |
0.23 |
| Mixed or multiple ethnic origins |
-0.30 |
-0.93 |
0.32 |
0.32 |
0.34 |
| Asian or Asian British |
-0.53 |
-1.42 |
0.35 |
0.45 |
0.23 |
| African or African British |
-0.16 |
-1.60 |
1.28 |
0.73 |
0.83 |
| Other ethnicity |
-0.12 |
-1.24 |
1.00 |
0.57 |
0.84 |
| Time difference: Lockdown to baseline |
-0.08 |
-0.13 |
-0.04 |
0.02 |
7.29e-04 |
| 14206 |
0.01 |
0.01 |
31.21 |
1.73e-37 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.63 |
2.20 |
3.05 |
0.22 |
1.95e-33 |
| Depressive and anxiety disorder |
0.84 |
0.60 |
1.08 |
0.12 |
3.13e-12 |
| Only depressive disorder |
0.70 |
0.40 |
1.01 |
0.16 |
6.54e-06 |
| Only anxiety disorder |
0.28 |
-0.11 |
0.66 |
0.20 |
0.16 |
| Eating disorders |
0.36 |
0.04 |
0.68 |
0.16 |
0.03 |
| OCDs |
-0.10 |
-0.40 |
0.21 |
0.16 |
0.53 |
| Psychotic and bipolar disorder |
-0.55 |
-1.47 |
0.37 |
0.47 |
0.24 |
| Only psychotic disorder |
-0.26 |
-1.01 |
0.49 |
0.38 |
0.50 |
| Only bipolar disorder |
0.01 |
-0.45 |
0.47 |
0.23 |
0.97 |
| PTSD |
0.64 |
0.35 |
0.93 |
0.15 |
1.45e-05 |
| ASD |
-0.07 |
-0.65 |
0.52 |
0.30 |
0.83 |
| ADHD |
0.09 |
-0.70 |
0.88 |
0.40 |
0.82 |
| Personality disorder |
0.32 |
-0.09 |
0.72 |
0.21 |
0.13 |
| Female |
0.44 |
0.22 |
0.66 |
0.11 |
9.60e-05 |
| Non-binary/Self-defined |
-0.65 |
-1.39 |
0.08 |
0.38 |
0.08 |
| Age |
-73.53 |
-86.03 |
-61.02 |
6.38 |
1.39e-30 |
| Age^2 |
12.99 |
1.14 |
24.84 |
6.05 |
0.03 |
| Mixed or multiple ethnic origins |
-0.28 |
-0.91 |
0.34 |
0.32 |
0.37 |
| Asian or Asian British |
-0.41 |
-1.27 |
0.45 |
0.44 |
0.35 |
| African or African British |
-0.14 |
-1.54 |
1.27 |
0.72 |
0.85 |
| Other ethnicity |
-0.30 |
-1.40 |
0.80 |
0.56 |
0.59 |
| Key worker |
0.27 |
0.09 |
0.45 |
0.09 |
0.004 |
| Time difference: Lockdown to baseline |
-0.08 |
-0.13 |
-0.03 |
0.02 |
7.77e-04 |
| 14206 |
0.01 |
0.01 |
31.21 |
1.73e-37 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.98 |
3.84 |
4.12 |
0.07 |
0.00e+00 |
| phq.sum_score_retro |
0.67 |
0.65 |
0.68 |
0.01 |
0.00e+00 |
| Anxiety disorders |
1.27 |
0.96 |
1.58 |
0.16 |
5.42e-16 |
| Eating disorders |
1.44 |
0.52 |
2.36 |
0.47 |
0.002 |
| OCDs |
2.27 |
1.53 |
3.01 |
0.38 |
1.97e-09 |
| PTSD |
2.06 |
1.30 |
2.83 |
0.39 |
1.05e-07 |
| Depressive disorders |
2.53 |
2.35 |
2.70 |
0.09 |
4.76e-173 |
| Bipolar disorders |
3.32 |
2.94 |
3.70 |
0.19 |
7.81e-66 |
| 19512 |
0.43 |
0.43 |
2104.41 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
4.22 |
4.09 |
4.36 |
0.07 |
0.00e+00 |
| phq.sum_score_retro |
0.63 |
0.61 |
0.64 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.33 |
2.15 |
2.51 |
0.09 |
1.27e-140 |
| Only depressive disorder |
1.19 |
0.96 |
1.42 |
0.12 |
1.20e-24 |
| Only anxiety disorder |
1.22 |
0.94 |
1.49 |
0.14 |
9.57e-18 |
| Eating disorders |
1.08 |
0.81 |
1.34 |
0.14 |
1.85e-15 |
| OCDs |
0.78 |
0.52 |
1.03 |
0.13 |
2.12e-09 |
| Psychotic and bipolar disorder |
-0.59 |
-1.32 |
0.14 |
0.37 |
0.12 |
| Only psychotic disorder |
-0.16 |
-0.80 |
0.48 |
0.32 |
0.62 |
| Only bipolar disorder |
0.45 |
0.05 |
0.84 |
0.20 |
0.03 |
| PTSD |
1.01 |
0.77 |
1.25 |
0.12 |
8.41e-17 |
| ASD |
1.31 |
0.85 |
1.76 |
0.23 |
1.83e-08 |
| ADHD |
0.74 |
0.13 |
1.35 |
0.31 |
0.02 |
| Personality disorder |
1.39 |
1.05 |
1.73 |
0.17 |
1.23e-15 |
| 23090 |
0.18 |
0.18 |
844.05 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.76 |
5.40 |
6.12 |
0.18 |
7.54e-213 |
| phq.sum_score_retro |
0.62 |
0.60 |
0.63 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.78 |
0.46 |
1.10 |
0.16 |
1.72e-06 |
| Eating disorders |
0.80 |
-0.13 |
1.73 |
0.48 |
0.09 |
| OCDs |
1.22 |
0.47 |
1.97 |
0.38 |
0.001 |
| PTSD |
1.72 |
0.94 |
2.50 |
0.40 |
1.57e-05 |
| Depressive disorders |
2.37 |
2.18 |
2.56 |
0.10 |
3.02e-132 |
| Bipolar disorders |
3.26 |
2.88 |
3.65 |
0.20 |
1.30e-61 |
| Female |
0.76 |
0.57 |
0.95 |
0.10 |
1.27e-15 |
| Non-binary/Self-defined |
0.96 |
0.33 |
1.59 |
0.32 |
0.003 |
| age_category_collapsed_reordered16-18 |
2.80 |
2.39 |
3.21 |
0.21 |
4.59e-41 |
| 19-25 years |
1.27 |
0.99 |
1.54 |
0.14 |
7.88e-19 |
| 36-45 years |
-0.47 |
-0.72 |
-0.23 |
0.12 |
1.43e-04 |
| 46-55 years |
-0.56 |
-0.79 |
-0.33 |
0.12 |
2.13e-06 |
| 56-65 years |
-1.00 |
-1.24 |
-0.77 |
0.12 |
9.46e-17 |
| 66-70 years |
-1.70 |
-2.04 |
-1.35 |
0.18 |
6.23e-22 |
| 71-75 years |
-1.79 |
-2.21 |
-1.36 |
0.22 |
2.16e-16 |
| 76+ years |
-1.86 |
-2.58 |
-1.14 |
0.37 |
4.02e-07 |
| Mixed or multiple ethnic origins |
-0.02 |
-0.54 |
0.49 |
0.26 |
0.93 |
| Asian or Asian British |
-0.10 |
-0.76 |
0.56 |
0.34 |
0.76 |
| African or African British |
-0.15 |
-1.25 |
0.94 |
0.56 |
0.78 |
| Other ethnicity |
0.06 |
-0.87 |
0.98 |
0.47 |
0.91 |
| Key worker |
-0.17 |
-0.33 |
-0.02 |
0.08 |
0.03 |
| Time difference: Lockdown to baseline |
-0.22 |
-0.26 |
-0.19 |
0.02 |
3.56e-37 |
| 23090 |
0.18 |
0.18 |
844.05 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.82 |
5.47 |
6.17 |
0.18 |
1.94e-227 |
| phq.sum_score_retro |
0.58 |
0.57 |
0.60 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.24 |
2.05 |
2.44 |
0.10 |
2.38e-114 |
| Only depressive disorder |
1.39 |
1.15 |
1.63 |
0.12 |
4.57e-30 |
| Only anxiety disorder |
0.79 |
0.50 |
1.08 |
0.15 |
8.38e-08 |
| Eating disorders |
0.81 |
0.54 |
1.08 |
0.14 |
2.63e-09 |
| OCDs |
0.58 |
0.32 |
0.84 |
0.13 |
8.74e-06 |
| Psychotic and bipolar disorder |
-0.30 |
-1.02 |
0.43 |
0.37 |
0.42 |
| Only psychotic disorder |
-0.01 |
-0.64 |
0.63 |
0.32 |
0.99 |
| Only bipolar disorder |
0.65 |
0.26 |
1.05 |
0.20 |
0.001 |
| PTSD |
1.10 |
0.86 |
1.34 |
0.12 |
2.66e-19 |
| ASD |
0.74 |
0.28 |
1.20 |
0.24 |
0.002 |
| ADHD |
0.54 |
-0.08 |
1.15 |
0.31 |
0.09 |
| Personality disorder |
1.41 |
1.06 |
1.75 |
0.17 |
7.55e-16 |
| Female |
0.66 |
0.47 |
0.84 |
0.09 |
2.66e-12 |
| Non-binary/Self-defined |
0.48 |
-0.14 |
1.10 |
0.32 |
0.13 |
| age_category_collapsed_reordered16-18 |
3.12 |
2.73 |
3.52 |
0.20 |
1.50e-54 |
| 19-25 years |
1.27 |
1.00 |
1.55 |
0.14 |
9.47e-20 |
| 36-45 years |
-0.44 |
-0.68 |
-0.20 |
0.12 |
3.64e-04 |
| 46-55 years |
-0.44 |
-0.66 |
-0.21 |
0.12 |
1.79e-04 |
| 56-65 years |
-0.78 |
-1.02 |
-0.55 |
0.12 |
6.23e-11 |
| 66-70 years |
-1.37 |
-1.71 |
-1.03 |
0.17 |
2.87e-15 |
| 71-75 years |
-1.45 |
-1.87 |
-1.03 |
0.21 |
1.21e-11 |
| 76+ years |
-1.57 |
-2.27 |
-0.87 |
0.36 |
1.15e-05 |
| Mixed or multiple ethnic origins |
0.07 |
-0.44 |
0.57 |
0.26 |
0.80 |
| Asian or Asian British |
0.18 |
-0.45 |
0.81 |
0.32 |
0.57 |
| African or African British |
-0.01 |
-1.08 |
1.06 |
0.54 |
0.98 |
| Other ethnicity |
-0.13 |
-1.02 |
0.76 |
0.45 |
0.77 |
| Key worker |
-0.08 |
-0.23 |
0.07 |
0.08 |
0.29 |
| Time difference: Lockdown to baseline |
-0.23 |
-0.26 |
-0.19 |
0.02 |
6.65e-39 |
| 23090 |
0.18 |
0.18 |
844.05 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.43 |
3.03 |
3.83 |
0.20 |
3.48e-62 |
| phq.sum_score_retro |
0.63 |
0.62 |
0.65 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.83 |
0.44 |
1.22 |
0.20 |
2.94e-05 |
| Eating disorders |
1.25 |
0.12 |
2.38 |
0.58 |
0.03 |
| OCDs |
1.51 |
0.57 |
2.44 |
0.48 |
0.002 |
| PTSD |
2.16 |
1.06 |
3.25 |
0.56 |
1.13e-04 |
| Depressive disorders |
2.69 |
2.47 |
2.92 |
0.12 |
2.45e-118 |
| Bipolar disorders |
3.52 |
3.10 |
3.95 |
0.22 |
1.37e-58 |
| Female |
0.51 |
0.30 |
0.71 |
0.10 |
1.28e-06 |
| Non-binary/Self-defined |
0.32 |
-0.37 |
1.00 |
0.35 |
0.36 |
| Age |
-119.55 |
-131.11 |
-107.99 |
5.90 |
5.87e-90 |
| Age^2 |
11.33 |
0.25 |
22.41 |
5.65 |
0.05 |
| Mixed or multiple ethnic origins |
-0.09 |
-0.67 |
0.49 |
0.30 |
0.76 |
| Asian or Asian British |
-0.26 |
-1.07 |
0.56 |
0.42 |
0.54 |
| African or African British |
-0.16 |
-1.49 |
1.17 |
0.68 |
0.82 |
| Other ethnicity |
0.34 |
-0.71 |
1.39 |
0.53 |
0.52 |
| Key worker |
-0.17 |
-0.34 |
0.00 |
0.09 |
0.05 |
| Time difference: Lockdown to baseline |
-0.04 |
-0.08 |
0.01 |
0.02 |
0.12 |
| 16833 |
0.23 |
0.23 |
815.64 |
0.00e+00 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.54 |
3.15 |
3.94 |
0.20 |
3.53e-69 |
| phq.sum_score_retro |
0.60 |
0.59 |
0.62 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
2.55 |
2.32 |
2.78 |
0.12 |
2.42e-105 |
| Only depressive disorder |
1.74 |
1.45 |
2.02 |
0.14 |
5.79e-33 |
| Only anxiety disorder |
0.91 |
0.56 |
1.27 |
0.18 |
4.19e-07 |
| Eating disorders |
0.84 |
0.55 |
1.14 |
0.15 |
2.07e-08 |
| OCDs |
0.45 |
0.17 |
0.74 |
0.14 |
0.002 |
| Psychotic and bipolar disorder |
-0.36 |
-1.20 |
0.49 |
0.43 |
0.41 |
| Only psychotic disorder |
0.12 |
-0.56 |
0.81 |
0.35 |
0.72 |
| Only bipolar disorder |
0.62 |
0.20 |
1.04 |
0.21 |
0.004 |
| PTSD |
1.11 |
0.85 |
1.38 |
0.14 |
2.08e-16 |
| ASD |
0.52 |
-0.02 |
1.06 |
0.28 |
0.06 |
| ADHD |
0.51 |
-0.22 |
1.23 |
0.37 |
0.17 |
| Personality disorder |
1.30 |
0.93 |
1.67 |
0.19 |
8.20e-12 |
| Female |
0.37 |
0.17 |
0.58 |
0.10 |
3.07e-04 |
| Non-binary/Self-defined |
-0.03 |
-0.71 |
0.64 |
0.35 |
0.92 |
| Age |
-109.60 |
-121.17 |
-98.04 |
5.90 |
4.38e-76 |
| Age^2 |
15.56 |
4.69 |
26.44 |
5.55 |
0.005 |
| Mixed or multiple ethnic origins |
-0.09 |
-0.66 |
0.48 |
0.29 |
0.76 |
| Asian or Asian British |
-0.06 |
-0.85 |
0.73 |
0.40 |
0.88 |
| African or African British |
-0.12 |
-1.41 |
1.17 |
0.66 |
0.86 |
| Other ethnicity |
0.08 |
-0.93 |
1.09 |
0.51 |
0.87 |
| Key worker |
-0.07 |
-0.24 |
0.10 |
0.09 |
0.40 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.07 |
0.02 |
0.02 |
0.20 |
| 16833 |
0.23 |
0.23 |
815.64 |
0.00e+00 |
6 |
PHQ retro: Sensitivity
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.75 |
1.61 |
3.89 |
0.58 |
2.21e-06 |
| Anxiety disorders |
0.64 |
-0.62 |
1.90 |
0.64 |
0.32 |
| Eating disorders |
0.84 |
-1.60 |
3.28 |
1.25 |
0.50 |
| OCDs |
0.73 |
-0.96 |
2.42 |
0.86 |
0.40 |
| PTSD |
1.07 |
-0.87 |
3.01 |
0.99 |
0.28 |
| Depressive disorders |
0.99 |
-0.15 |
2.14 |
0.59 |
0.09 |
| Bipolar disorders |
0.79 |
-0.44 |
2.02 |
0.63 |
0.21 |
| 8319 |
0.00 |
0.00 |
0.83 |
0.55 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
2.95 |
2.13 |
3.77 |
0.42 |
1.94e-12 |
| Depressive and anxiety disorder |
0.68 |
-0.16 |
1.51 |
0.42 |
0.11 |
| Only depressive disorder |
0.48 |
-0.42 |
1.38 |
0.46 |
0.30 |
| Only anxiety disorder |
0.50 |
-0.44 |
1.44 |
0.48 |
0.30 |
| Eating disorders |
0.55 |
0.16 |
0.95 |
0.20 |
0.006 |
| OCDs |
-0.12 |
-0.49 |
0.24 |
0.19 |
0.51 |
| Psychotic and bipolar disorder |
-0.74 |
-1.85 |
0.38 |
0.57 |
0.19 |
| Only psychotic disorder |
-0.46 |
-1.38 |
0.47 |
0.47 |
0.33 |
| Only bipolar disorder |
-0.27 |
-0.81 |
0.27 |
0.28 |
0.33 |
| PTSD |
0.43 |
0.09 |
0.78 |
0.18 |
0.01 |
| ASD |
0.01 |
-0.70 |
0.71 |
0.36 |
0.99 |
| ADHD |
0.27 |
-0.72 |
1.26 |
0.50 |
0.59 |
| Personality disorder |
0.38 |
-0.10 |
0.86 |
0.25 |
0.12 |
| 8319 |
0.00 |
0.00 |
0.83 |
0.55 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.01 |
1.69 |
4.33 |
0.67 |
8.01e-06 |
| Anxiety disorders |
0.51 |
-0.75 |
1.76 |
0.64 |
0.43 |
| Eating disorders |
0.54 |
-1.89 |
2.97 |
1.24 |
0.66 |
| OCDs |
0.41 |
-1.28 |
2.09 |
0.86 |
0.64 |
| PTSD |
1.08 |
-0.87 |
3.03 |
0.99 |
0.28 |
| Depressive disorders |
1.02 |
-0.13 |
2.17 |
0.58 |
0.08 |
| Bipolar disorders |
0.93 |
-0.30 |
2.16 |
0.63 |
0.14 |
| Female |
0.57 |
0.22 |
0.91 |
0.17 |
0.001 |
| Non-binary/Self-defined |
-0.47 |
-1.39 |
0.45 |
0.47 |
0.32 |
| age_category_collapsed_reordered16-18 |
0.70 |
-0.05 |
1.44 |
0.38 |
0.07 |
| 19-25 years |
0.63 |
0.22 |
1.04 |
0.21 |
0.003 |
| 36-45 years |
-0.37 |
-0.74 |
0.00 |
0.19 |
0.05 |
| 46-55 years |
-0.40 |
-0.77 |
-0.04 |
0.19 |
0.03 |
| 56-65 years |
-1.13 |
-1.55 |
-0.71 |
0.21 |
1.32e-07 |
| 66-70 years |
-1.17 |
-1.97 |
-0.38 |
0.40 |
0.004 |
| 71-75 years |
-1.96 |
-3.09 |
-0.83 |
0.58 |
7.07e-04 |
| 76+ years |
-1.95 |
-4.20 |
0.30 |
1.15 |
0.09 |
| Mixed or multiple ethnic origins |
-0.57 |
-1.40 |
0.26 |
0.42 |
0.18 |
| Asian or Asian British |
-0.86 |
-2.18 |
0.47 |
0.68 |
0.21 |
| African or African British |
-0.29 |
-2.33 |
1.76 |
1.04 |
0.78 |
| Other ethnicity |
-0.29 |
-1.60 |
1.02 |
0.67 |
0.66 |
| Time difference: Lockdown to baseline |
-0.06 |
-0.14 |
0.01 |
0.04 |
0.10 |
| 8319 |
0.00 |
0.00 |
0.83 |
0.55 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
3.08 |
2.01 |
4.15 |
0.55 |
1.94e-08 |
| Depressive and anxiety disorder |
0.77 |
-0.07 |
1.60 |
0.43 |
0.07 |
| Only depressive disorder |
0.80 |
-0.11 |
1.71 |
0.46 |
0.08 |
| Only anxiety disorder |
0.42 |
-0.52 |
1.37 |
0.48 |
0.38 |
| Eating disorders |
0.40 |
0.01 |
0.80 |
0.20 |
0.05 |
| OCDs |
-0.17 |
-0.54 |
0.19 |
0.19 |
0.36 |
| Psychotic and bipolar disorder |
-0.49 |
-1.61 |
0.62 |
0.57 |
0.38 |
| Only psychotic disorder |
-0.23 |
-1.15 |
0.70 |
0.47 |
0.63 |
| Only bipolar disorder |
-0.10 |
-0.65 |
0.44 |
0.28 |
0.71 |
| PTSD |
0.48 |
0.13 |
0.83 |
0.18 |
0.007 |
| ASD |
-0.09 |
-0.80 |
0.63 |
0.36 |
0.81 |
| ADHD |
0.28 |
-0.70 |
1.27 |
0.50 |
0.57 |
| Personality disorder |
0.32 |
-0.16 |
0.80 |
0.25 |
0.19 |
| Female |
0.49 |
0.14 |
0.83 |
0.18 |
0.005 |
| Non-binary/Self-defined |
-0.55 |
-1.47 |
0.37 |
0.47 |
0.24 |
| age_category_collapsed_reordered16-18 |
0.80 |
0.06 |
1.54 |
0.38 |
0.03 |
| 19-25 years |
0.64 |
0.23 |
1.05 |
0.21 |
0.002 |
| 36-45 years |
-0.37 |
-0.74 |
0.00 |
0.19 |
0.05 |
| 46-55 years |
-0.41 |
-0.78 |
-0.04 |
0.19 |
0.03 |
| 56-65 years |
-1.08 |
-1.51 |
-0.66 |
0.22 |
6.34e-07 |
| 66-70 years |
-1.01 |
-1.81 |
-0.22 |
0.41 |
0.01 |
| 71-75 years |
-1.71 |
-2.84 |
-0.58 |
0.58 |
0.003 |
| 76+ years |
-1.75 |
-3.99 |
0.50 |
1.15 |
0.13 |
| Mixed or multiple ethnic origins |
-0.58 |
-1.41 |
0.25 |
0.42 |
0.17 |
| Asian or Asian British |
-0.75 |
-2.07 |
0.56 |
0.67 |
0.26 |
| African or African British |
-0.20 |
-2.24 |
1.84 |
1.04 |
0.85 |
| Other ethnicity |
-0.44 |
-1.73 |
0.85 |
0.66 |
0.50 |
| Key worker |
0.24 |
-0.01 |
0.50 |
0.13 |
0.06 |
| Time difference: Lockdown to baseline |
-0.06 |
-0.14 |
0.01 |
0.04 |
0.10 |
| 8319 |
0.00 |
0.00 |
0.83 |
0.55 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
5.30 |
4.25 |
6.35 |
0.54 |
8.28e-23 |
| phq.sum_score_retro |
0.61 |
0.60 |
0.63 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.02 |
-1.14 |
1.17 |
0.59 |
0.98 |
| Eating disorders |
1.40 |
-0.84 |
3.65 |
1.14 |
0.22 |
| OCDs |
1.16 |
-0.39 |
2.71 |
0.79 |
0.14 |
| PTSD |
1.08 |
-0.70 |
2.86 |
0.91 |
0.24 |
| Depressive disorders |
1.56 |
0.51 |
2.62 |
0.54 |
0.004 |
| Bipolar disorders |
2.10 |
0.97 |
3.24 |
0.58 |
2.74e-04 |
| 8319 |
0.34 |
0.34 |
602.29 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
5.91 |
5.15 |
6.67 |
0.39 |
7.36e-52 |
| phq.sum_score_retro |
0.59 |
0.57 |
0.61 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.80 |
0.04 |
1.56 |
0.39 |
0.04 |
| Only depressive disorder |
0.18 |
-0.64 |
1.00 |
0.42 |
0.67 |
| Only anxiety disorder |
-0.35 |
-1.20 |
0.51 |
0.44 |
0.43 |
| Eating disorders |
1.04 |
0.69 |
1.40 |
0.18 |
1.14e-08 |
| OCDs |
0.51 |
0.17 |
0.84 |
0.17 |
0.003 |
| Psychotic and bipolar disorder |
-0.75 |
-1.77 |
0.26 |
0.52 |
0.15 |
| Only psychotic disorder |
-0.14 |
-0.98 |
0.70 |
0.43 |
0.74 |
| Only bipolar disorder |
0.25 |
-0.24 |
0.75 |
0.25 |
0.31 |
| PTSD |
0.84 |
0.52 |
1.15 |
0.16 |
1.90e-07 |
| ASD |
0.72 |
0.07 |
1.36 |
0.33 |
0.03 |
| ADHD |
0.73 |
-0.17 |
1.62 |
0.46 |
0.11 |
| Personality disorder |
1.50 |
1.06 |
1.94 |
0.22 |
3.07e-11 |
| 9687 |
0.02 |
0.02 |
39.82 |
3.86e-48 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.37 |
4.15 |
6.60 |
0.63 |
1.15e-17 |
| phq.sum_score_retro |
0.59 |
0.57 |
0.61 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.01 |
-1.14 |
1.17 |
0.59 |
0.98 |
| Eating disorders |
1.28 |
-0.94 |
3.50 |
1.13 |
0.26 |
| OCDs |
0.89 |
-0.65 |
2.43 |
0.79 |
0.26 |
| PTSD |
1.38 |
-0.40 |
3.16 |
0.91 |
0.13 |
| Depressive disorders |
1.87 |
0.81 |
2.93 |
0.54 |
5.19e-04 |
| Bipolar disorders |
2.56 |
1.42 |
3.70 |
0.58 |
1.02e-05 |
| Female |
0.45 |
0.14 |
0.76 |
0.16 |
0.005 |
| Non-binary/Self-defined |
0.50 |
-0.34 |
1.34 |
0.43 |
0.25 |
| age_category_collapsed_reordered16-18 |
2.02 |
1.34 |
2.71 |
0.35 |
7.28e-09 |
| 19-25 years |
1.03 |
0.66 |
1.41 |
0.19 |
7.37e-08 |
| 36-45 years |
-0.37 |
-0.71 |
-0.03 |
0.17 |
0.03 |
| 46-55 years |
-0.37 |
-0.70 |
-0.03 |
0.17 |
0.03 |
| 56-65 years |
-1.27 |
-1.66 |
-0.89 |
0.20 |
1.12e-10 |
| 66-70 years |
-2.06 |
-2.80 |
-1.33 |
0.37 |
3.26e-08 |
| 71-75 years |
-2.77 |
-3.80 |
-1.73 |
0.53 |
1.84e-07 |
| 76+ years |
-2.39 |
-4.44 |
-0.34 |
1.05 |
0.02 |
| Mixed or multiple ethnic origins |
-0.33 |
-1.10 |
0.43 |
0.39 |
0.39 |
| Asian or Asian British |
-0.56 |
-1.77 |
0.64 |
0.62 |
0.36 |
| African or African British |
-0.30 |
-2.16 |
1.56 |
0.95 |
0.75 |
| Other ethnicity |
0.03 |
-1.17 |
1.24 |
0.61 |
0.96 |
| Key worker |
-0.35 |
-0.58 |
-0.11 |
0.12 |
0.004 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.10 |
0.04 |
0.04 |
0.39 |
| 9687 |
0.02 |
0.02 |
39.82 |
3.86e-48 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.03 |
5.05 |
7.01 |
0.50 |
3.16e-33 |
| phq.sum_score_retro |
0.57 |
0.55 |
0.59 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
1.05 |
0.30 |
1.81 |
0.39 |
0.006 |
| Only depressive disorder |
0.71 |
-0.10 |
1.53 |
0.42 |
0.09 |
| Only anxiety disorder |
-0.39 |
-1.24 |
0.47 |
0.44 |
0.37 |
| Eating disorders |
0.88 |
0.52 |
1.24 |
0.18 |
1.37e-06 |
| OCDs |
0.43 |
0.09 |
0.76 |
0.17 |
0.01 |
| Psychotic and bipolar disorder |
-0.49 |
-1.49 |
0.52 |
0.51 |
0.34 |
| Only psychotic disorder |
0.05 |
-0.79 |
0.88 |
0.43 |
0.91 |
| Only bipolar disorder |
0.45 |
-0.04 |
0.94 |
0.25 |
0.07 |
| PTSD |
0.93 |
0.61 |
1.24 |
0.16 |
7.73e-09 |
| ASD |
0.33 |
-0.31 |
0.98 |
0.33 |
0.31 |
| ADHD |
0.64 |
-0.26 |
1.53 |
0.45 |
0.16 |
| Personality disorder |
1.40 |
0.97 |
1.84 |
0.22 |
3.86e-10 |
| Female |
0.26 |
-0.05 |
0.57 |
0.16 |
0.10 |
| Non-binary/Self-defined |
0.11 |
-0.72 |
0.94 |
0.42 |
0.80 |
| age_category_collapsed_reordered16-18 |
2.16 |
1.49 |
2.83 |
0.34 |
3.01e-10 |
| 19-25 years |
1.02 |
0.65 |
1.39 |
0.19 |
6.87e-08 |
| 36-45 years |
-0.35 |
-0.68 |
-0.01 |
0.17 |
0.04 |
| 46-55 years |
-0.31 |
-0.64 |
0.03 |
0.17 |
0.07 |
| 56-65 years |
-1.14 |
-1.53 |
-0.76 |
0.20 |
6.06e-09 |
| 66-70 years |
-1.83 |
-2.55 |
-1.10 |
0.37 |
7.29e-07 |
| 71-75 years |
-2.41 |
-3.43 |
-1.39 |
0.52 |
3.93e-06 |
| 76+ years |
-2.09 |
-4.12 |
-0.06 |
1.04 |
0.04 |
| Mixed or multiple ethnic origins |
-0.41 |
-1.16 |
0.34 |
0.38 |
0.28 |
| Asian or Asian British |
-0.43 |
-1.62 |
0.76 |
0.61 |
0.48 |
| African or African British |
-0.10 |
-1.95 |
1.74 |
0.94 |
0.91 |
| Other ethnicity |
-0.20 |
-1.36 |
0.96 |
0.59 |
0.74 |
| Key worker |
-0.25 |
-0.48 |
-0.01 |
0.12 |
0.04 |
| Time difference: Lockdown to baseline |
-0.02 |
-0.09 |
0.04 |
0.03 |
0.48 |
| 9687 |
0.02 |
0.02 |
39.82 |
3.86e-48 |
6 |
OCI-R baseline, not controlling for prior symptoms
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
12.34 |
11.53 |
13.16 |
0.41 |
2.57e-180 |
| Anxiety disorders |
2.05 |
0.59 |
3.52 |
0.75 |
0.006 |
| Eating disorders |
4.27 |
0.09 |
8.44 |
2.13 |
0.05 |
| OCDs |
10.43 |
7.72 |
13.15 |
1.38 |
5.70e-14 |
| PTSD |
6.78 |
3.74 |
9.83 |
1.55 |
1.30e-05 |
| Depressive disorders |
5.74 |
4.83 |
6.66 |
0.47 |
3.07e-34 |
| Bipolar disorders |
12.77 |
11.15 |
14.38 |
0.82 |
4.97e-53 |
| 5187 |
0.06 |
0.06 |
52.91 |
1.40e-63 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
13.33 |
12.63 |
14.03 |
0.36 |
1.93e-271 |
| Depressive and anxiety disorder |
2.50 |
1.63 |
3.36 |
0.44 |
1.64e-08 |
| Only depressive disorder |
-0.78 |
-1.98 |
0.41 |
0.61 |
0.20 |
| Only anxiety disorder |
0.78 |
-0.45 |
2.01 |
0.63 |
0.21 |
| Eating disorders |
0.62 |
-0.45 |
1.68 |
0.54 |
0.26 |
| OCDs |
7.47 |
6.53 |
8.41 |
0.48 |
1.21e-53 |
| Psychotic and bipolar disorder |
7.02 |
4.50 |
9.54 |
1.29 |
5.11e-08 |
| Only psychotic disorder |
4.35 |
2.05 |
6.65 |
1.17 |
2.09e-04 |
| Only bipolar disorder |
3.31 |
1.66 |
4.97 |
0.84 |
8.90e-05 |
| PTSD |
1.96 |
1.03 |
2.89 |
0.47 |
3.42e-05 |
| ASD |
9.07 |
7.38 |
10.75 |
0.86 |
7.54e-26 |
| ADHD |
2.71 |
0.39 |
5.03 |
1.18 |
0.02 |
| Personality disorder |
3.43 |
2.16 |
4.71 |
0.65 |
1.23e-07 |
| 5187 |
0.06 |
0.06 |
52.91 |
1.40e-63 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
15.44 |
13.75 |
17.13 |
0.86 |
2.03e-69 |
| Anxiety disorders |
1.67 |
0.21 |
3.14 |
0.75 |
0.03 |
| Eating disorders |
3.33 |
-0.84 |
7.49 |
2.13 |
0.12 |
| OCDs |
8.67 |
5.97 |
11.37 |
1.38 |
3.21e-10 |
| PTSD |
6.49 |
3.45 |
9.53 |
1.55 |
2.85e-05 |
| Depressive disorders |
6.05 |
5.10 |
7.00 |
0.48 |
2.77e-35 |
| Bipolar disorders |
12.70 |
11.08 |
14.33 |
0.83 |
6.51e-52 |
| Female |
-0.91 |
-1.87 |
0.05 |
0.49 |
0.06 |
| Non-binary/Self-defined |
1.82 |
-0.80 |
4.45 |
1.34 |
0.17 |
| age_category_collapsed_reordered16-18 |
8.24 |
6.60 |
9.89 |
0.84 |
1.47e-22 |
| 19-25 years |
1.70 |
0.39 |
3.01 |
0.67 |
0.01 |
| 36-45 years |
-0.47 |
-1.69 |
0.74 |
0.62 |
0.45 |
| 46-55 years |
-0.67 |
-1.78 |
0.45 |
0.57 |
0.24 |
| 56-65 years |
-1.89 |
-3.00 |
-0.78 |
0.57 |
8.48e-04 |
| 66-70 years |
-2.50 |
-4.13 |
-0.88 |
0.83 |
0.003 |
| 71-75 years |
-3.47 |
-5.45 |
-1.49 |
1.01 |
5.92e-04 |
| 76+ years |
-4.77 |
-8.43 |
-1.11 |
1.87 |
0.01 |
| Mixed or multiple ethnic origins |
1.17 |
-1.15 |
3.50 |
1.19 |
0.32 |
| Asian or Asian British |
4.45 |
1.34 |
7.56 |
1.59 |
0.005 |
| African or African British |
3.10 |
-2.44 |
8.65 |
2.83 |
0.27 |
| Other ethnicity |
2.59 |
-0.83 |
6.02 |
1.75 |
0.14 |
| Time difference: Lockdown to baseline |
-0.39 |
-0.56 |
-0.23 |
0.08 |
1.84e-06 |
| 5187 |
0.06 |
0.06 |
52.91 |
1.40e-63 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
15.69 |
14.10 |
17.29 |
0.81 |
4.46e-80 |
| Depressive and anxiety disorder |
3.34 |
2.44 |
4.24 |
0.46 |
3.43e-13 |
| Only depressive disorder |
0.35 |
-0.86 |
1.55 |
0.62 |
0.58 |
| Only anxiety disorder |
0.92 |
-0.31 |
2.16 |
0.63 |
0.14 |
| Eating disorders |
0.25 |
-0.81 |
1.31 |
0.54 |
0.64 |
| OCDs |
7.03 |
6.10 |
7.96 |
0.48 |
2.32e-48 |
| Psychotic and bipolar disorder |
6.97 |
4.48 |
9.46 |
1.27 |
4.23e-08 |
| Only psychotic disorder |
3.92 |
1.66 |
6.19 |
1.15 |
6.78e-04 |
| Only bipolar disorder |
3.29 |
1.64 |
4.93 |
0.84 |
9.11e-05 |
| PTSD |
2.30 |
1.38 |
3.23 |
0.47 |
1.14e-06 |
| ASD |
7.54 |
5.85 |
9.24 |
0.86 |
3.53e-18 |
| ADHD |
1.68 |
-0.61 |
3.98 |
1.17 |
0.15 |
| Personality disorder |
3.36 |
2.10 |
4.63 |
0.64 |
1.82e-07 |
| Female |
-0.86 |
-1.78 |
0.05 |
0.47 |
0.06 |
| Non-binary/Self-defined |
-1.12 |
-3.62 |
1.38 |
1.28 |
0.38 |
| age_category_collapsed_reordered16-18 |
8.06 |
6.53 |
9.58 |
0.78 |
7.54e-25 |
| 19-25 years |
1.69 |
0.46 |
2.92 |
0.63 |
0.007 |
| 36-45 years |
-0.01 |
-1.17 |
1.14 |
0.59 |
0.98 |
| 46-55 years |
0.13 |
-0.93 |
1.20 |
0.54 |
0.80 |
| 56-65 years |
-0.62 |
-1.69 |
0.45 |
0.54 |
0.26 |
| 66-70 years |
-0.80 |
-2.38 |
0.79 |
0.81 |
0.32 |
| 71-75 years |
-1.91 |
-3.82 |
0.00 |
0.97 |
0.05 |
| 76+ years |
-3.54 |
-7.03 |
-0.05 |
1.78 |
0.05 |
| Mixed or multiple ethnic origins |
0.66 |
-1.55 |
2.86 |
1.13 |
0.56 |
| Asian or Asian British |
5.21 |
2.34 |
8.08 |
1.46 |
3.74e-04 |
| African or African British |
4.16 |
-0.98 |
9.30 |
2.62 |
0.11 |
| Other ethnicity |
1.40 |
-1.86 |
4.66 |
1.66 |
0.40 |
| Key worker |
-1.05 |
-1.76 |
-0.35 |
0.36 |
0.003 |
| Time difference: Lockdown to baseline |
-0.39 |
-0.54 |
-0.24 |
0.08 |
5.58e-07 |
| 5187 |
0.06 |
0.06 |
52.91 |
1.40e-63 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.35 |
3.59 |
9.10 |
1.41 |
6.71e-06 |
| Anxiety disorders |
0.17 |
-2.64 |
2.99 |
1.43 |
0.90 |
| Eating disorders |
8.06 |
2.15 |
13.98 |
3.02 |
0.008 |
| OCDs |
11.04 |
6.42 |
15.66 |
2.36 |
2.98e-06 |
| PTSD |
9.49 |
3.54 |
15.44 |
3.03 |
0.002 |
| Depressive disorders |
7.29 |
5.47 |
9.12 |
0.93 |
7.14e-15 |
| Bipolar disorders |
12.92 |
10.40 |
15.43 |
1.28 |
2.13e-23 |
| Female |
-0.44 |
-1.81 |
0.93 |
0.70 |
0.53 |
| Non-binary/Self-defined |
2.94 |
-0.64 |
6.52 |
1.82 |
0.11 |
| Age |
-228.51 |
-325.53 |
-131.48 |
49.48 |
4.09e-06 |
| Age^2 |
-37.91 |
-127.72 |
51.91 |
45.80 |
0.41 |
| Mixed or multiple ethnic origins |
1.96 |
-1.24 |
5.16 |
1.63 |
0.23 |
| Asian or Asian British |
10.02 |
3.52 |
16.52 |
3.32 |
0.003 |
| African or African British |
4.66 |
-4.87 |
14.20 |
4.86 |
0.34 |
| Other ethnicity |
3.60 |
-1.10 |
8.29 |
2.39 |
0.13 |
| Time difference: Lockdown to baseline |
0.29 |
0.02 |
0.56 |
0.14 |
0.03 |
| 2351 |
0.07 |
0.07 |
30.38 |
2.76e-35 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
8.06 |
5.49 |
10.63 |
1.31 |
9.66e-10 |
| Depressive and anxiety disorder |
4.47 |
2.83 |
6.10 |
0.83 |
9.06e-08 |
| Only depressive disorder |
2.32 |
0.15 |
4.49 |
1.11 |
0.04 |
| Only anxiety disorder |
0.91 |
-1.42 |
3.23 |
1.19 |
0.45 |
| Eating disorders |
1.43 |
-0.01 |
2.87 |
0.73 |
0.05 |
| OCDs |
6.94 |
5.67 |
8.21 |
0.65 |
2.50e-26 |
| Psychotic and bipolar disorder |
6.19 |
2.53 |
9.84 |
1.86 |
9.23e-04 |
| Only psychotic disorder |
3.02 |
0.07 |
5.97 |
1.50 |
0.04 |
| Only bipolar disorder |
3.51 |
1.41 |
5.61 |
1.07 |
0.001 |
| PTSD |
2.23 |
0.97 |
3.49 |
0.64 |
5.21e-04 |
| ASD |
6.10 |
3.40 |
8.80 |
1.38 |
9.63e-06 |
| ADHD |
0.07 |
-3.76 |
3.90 |
1.95 |
0.97 |
| Personality disorder |
2.76 |
1.10 |
4.41 |
0.84 |
0.001 |
| Female |
-0.76 |
-2.06 |
0.55 |
0.66 |
0.25 |
| Non-binary/Self-defined |
1.41 |
-2.04 |
4.86 |
1.76 |
0.42 |
| Age |
-166.95 |
-262.51 |
-71.39 |
48.73 |
6.24e-04 |
| Age^2 |
-38.78 |
-126.23 |
48.68 |
44.60 |
0.38 |
| Mixed or multiple ethnic origins |
1.11 |
-1.96 |
4.18 |
1.57 |
0.48 |
| Asian or Asian British |
8.94 |
2.96 |
14.92 |
3.05 |
0.003 |
| African or African British |
5.35 |
-3.71 |
14.42 |
4.62 |
0.25 |
| Other ethnicity |
1.58 |
-2.99 |
6.14 |
2.33 |
0.50 |
| Key worker |
-1.39 |
-2.39 |
-0.40 |
0.51 |
0.006 |
| Time difference: Lockdown to baseline |
0.26 |
0.01 |
0.51 |
0.13 |
0.04 |
| 2351 |
0.07 |
0.07 |
30.38 |
2.76e-35 |
6 |
OCIR prepan
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
2.00 |
-10.15 |
14.15 |
6.18 |
0.75 |
| Anxiety disorders |
-10.07 |
-23.37 |
3.24 |
6.77 |
0.14 |
| Eating disorders |
-8.00 |
-27.20 |
11.20 |
9.77 |
0.41 |
| OCDs |
-12.64 |
-26.34 |
1.07 |
6.97 |
0.07 |
| PTSD |
-24.50 |
-43.70 |
-5.30 |
9.77 |
0.01 |
| Depressive disorders |
-10.11 |
-22.30 |
2.09 |
6.20 |
0.10 |
| Bipolar disorders |
-9.36 |
-21.92 |
3.19 |
6.39 |
0.14 |
| 436 |
0.02 |
0.00 |
1.20 |
0.31 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
-1.97 |
-9.82 |
5.88 |
3.99 |
0.62 |
| Depressive and anxiety disorder |
-4.69 |
-12.65 |
3.26 |
4.05 |
0.25 |
| Only depressive disorder |
-4.49 |
-13.22 |
4.24 |
4.44 |
0.31 |
| Only anxiety disorder |
-8.20 |
-16.94 |
0.54 |
4.45 |
0.07 |
| Eating disorders |
-0.11 |
-2.79 |
2.58 |
1.37 |
0.94 |
| OCDs |
-1.25 |
-3.47 |
0.98 |
1.13 |
0.27 |
| Psychotic and bipolar disorder |
12.95 |
5.33 |
20.57 |
3.88 |
9.07e-04 |
| Only psychotic disorder |
-0.95 |
-6.48 |
4.59 |
2.82 |
0.74 |
| Only bipolar disorder |
-1.15 |
-4.80 |
2.50 |
1.86 |
0.54 |
| PTSD |
-3.79 |
-6.25 |
-1.33 |
1.25 |
0.003 |
| ASD |
-0.45 |
-4.77 |
3.88 |
2.20 |
0.84 |
| ADHD |
6.08 |
-0.41 |
12.57 |
3.30 |
0.07 |
| Personality disorder |
-1.65 |
-4.91 |
1.61 |
1.66 |
0.32 |
| 436 |
0.02 |
0.00 |
1.20 |
0.31 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
2.04 |
-11.93 |
16.02 |
7.11 |
0.77 |
| Anxiety disorders |
-8.89 |
-22.30 |
4.52 |
6.82 |
0.19 |
| Eating disorders |
-6.73 |
-25.88 |
12.42 |
9.74 |
0.49 |
| OCDs |
-11.92 |
-25.71 |
1.86 |
7.01 |
0.09 |
| PTSD |
-23.03 |
-42.29 |
-3.77 |
9.80 |
0.02 |
| Depressive disorders |
-9.92 |
-22.25 |
2.40 |
6.27 |
0.11 |
| Bipolar disorders |
-9.57 |
-22.24 |
3.09 |
6.44 |
0.14 |
| Female |
-2.40 |
-5.48 |
0.68 |
1.57 |
0.13 |
| Non-binary/Self-defined |
-2.97 |
-8.90 |
2.96 |
3.02 |
0.33 |
| age_category_collapsed_reordered16-18 |
-7.23 |
-14.16 |
-0.30 |
3.52 |
0.04 |
| 19-25 years |
-3.44 |
-6.41 |
-0.48 |
1.51 |
0.02 |
| 36-45 years |
-0.26 |
-3.36 |
2.83 |
1.57 |
0.87 |
| 46-55 years |
-0.15 |
-3.14 |
2.84 |
1.52 |
0.92 |
| 56-65 years |
-2.75 |
-6.44 |
0.93 |
1.88 |
0.14 |
| 66-70 years |
-2.21 |
-8.75 |
4.32 |
3.32 |
0.51 |
| 71-75 years |
0.51 |
-11.60 |
12.62 |
6.16 |
0.93 |
| Mixed or multiple ethnic origins |
2.32 |
-4.36 |
8.99 |
3.40 |
0.50 |
| Asian or Asian British |
-25.07 |
-39.77 |
-10.37 |
7.48 |
8.73e-04 |
| African or African British |
17.03 |
-4.71 |
38.78 |
11.06 |
0.12 |
| Other ethnicity |
-1.26 |
-9.90 |
7.39 |
4.40 |
0.77 |
| Time difference: Lockdown to baseline |
0.46 |
-0.30 |
1.22 |
0.39 |
0.23 |
| 436 |
0.02 |
0.00 |
1.20 |
0.31 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.92 |
-14.68 |
6.84 |
5.47 |
0.47 |
| Depressive and anxiety disorder |
-4.23 |
-13.00 |
4.54 |
4.46 |
0.34 |
| Only depressive disorder |
-4.32 |
-13.77 |
5.14 |
4.81 |
0.37 |
| Only anxiety disorder |
-6.76 |
-16.24 |
2.72 |
4.82 |
0.16 |
| Eating disorders |
0.10 |
-2.63 |
2.83 |
1.39 |
0.94 |
| OCDs |
-1.13 |
-3.38 |
1.11 |
1.14 |
0.32 |
| Psychotic and bipolar disorder |
11.21 |
3.49 |
18.93 |
3.93 |
0.005 |
| Only psychotic disorder |
-1.54 |
-7.19 |
4.10 |
2.87 |
0.59 |
| Only bipolar disorder |
-1.19 |
-4.91 |
2.53 |
1.89 |
0.53 |
| PTSD |
-3.44 |
-5.97 |
-0.91 |
1.29 |
0.008 |
| ASD |
-0.47 |
-4.83 |
3.90 |
2.22 |
0.83 |
| ADHD |
5.20 |
-1.33 |
11.72 |
3.32 |
0.12 |
| Personality disorder |
-1.05 |
-4.32 |
2.23 |
1.67 |
0.53 |
| Female |
-1.66 |
-4.79 |
1.48 |
1.59 |
0.30 |
| Non-binary/Self-defined |
-1.50 |
-7.58 |
4.58 |
3.09 |
0.63 |
| age_category_collapsed_reordered16-18 |
-6.20 |
-13.06 |
0.66 |
3.49 |
0.08 |
| 19-25 years |
-3.51 |
-6.48 |
-0.54 |
1.51 |
0.02 |
| 36-45 years |
-0.52 |
-3.60 |
2.56 |
1.57 |
0.74 |
| 46-55 years |
-0.10 |
-3.12 |
2.92 |
1.54 |
0.95 |
| 56-65 years |
-2.08 |
-5.82 |
1.66 |
1.90 |
0.27 |
| 66-70 years |
-2.36 |
-8.96 |
4.25 |
3.36 |
0.48 |
| 71-75 years |
2.49 |
-8.24 |
13.22 |
5.46 |
0.65 |
| Mixed or multiple ethnic origins |
2.65 |
-4.05 |
9.34 |
3.41 |
0.44 |
| Asian or Asian British |
-22.96 |
-37.78 |
-8.15 |
7.54 |
0.002 |
| African or African British |
17.05 |
-4.50 |
38.59 |
10.96 |
0.12 |
| Other ethnicity |
-1.47 |
-10.07 |
7.14 |
4.38 |
0.74 |
| Key worker |
1.12 |
-1.09 |
3.33 |
1.12 |
0.32 |
| Time difference: Lockdown to baseline |
0.52 |
-0.23 |
1.27 |
0.38 |
0.17 |
| 436 |
0.02 |
0.00 |
1.20 |
0.31 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
0.82 |
-12.88 |
14.52 |
6.97 |
0.91 |
| Anxiety disorders |
-9.53 |
-22.75 |
3.69 |
6.73 |
0.16 |
| Eating disorders |
-5.99 |
-24.93 |
12.94 |
9.63 |
0.53 |
| OCDs |
-11.80 |
-25.29 |
1.68 |
6.86 |
0.09 |
| PTSD |
-23.80 |
-42.78 |
-4.82 |
9.65 |
0.01 |
| Depressive disorders |
-9.84 |
-21.94 |
2.26 |
6.16 |
0.11 |
| Bipolar disorders |
-9.78 |
-22.24 |
2.67 |
6.34 |
0.12 |
| Female |
-2.36 |
-5.43 |
0.70 |
1.56 |
0.13 |
| Non-binary/Self-defined |
-2.80 |
-8.69 |
3.09 |
3.00 |
0.35 |
| Age |
6.51 |
-113.13 |
126.16 |
60.87 |
0.91 |
| Age^2 |
-163.21 |
-285.29 |
-41.12 |
62.11 |
0.009 |
| Mixed or multiple ethnic origins |
2.26 |
-4.38 |
8.91 |
3.38 |
0.50 |
| Asian or Asian British |
-25.30 |
-39.96 |
-10.65 |
7.46 |
7.55e-04 |
| African or African British |
19.00 |
-2.12 |
40.11 |
10.74 |
0.08 |
| Other ethnicity |
-1.18 |
-9.78 |
7.43 |
4.38 |
0.79 |
| Time difference: Lockdown to baseline |
0.45 |
-0.30 |
1.21 |
0.38 |
0.24 |
| 436 |
0.02 |
0.00 |
1.20 |
0.31 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.88 |
-14.22 |
6.46 |
5.26 |
0.46 |
| Depressive and anxiety disorder |
-5.09 |
-13.66 |
3.49 |
4.36 |
0.24 |
| Only depressive disorder |
-5.61 |
-14.87 |
3.65 |
4.71 |
0.23 |
| Only anxiety disorder |
-8.09 |
-17.40 |
1.21 |
4.73 |
0.09 |
| Eating disorders |
0.06 |
-2.66 |
2.78 |
1.38 |
0.97 |
| OCDs |
-1.21 |
-3.43 |
1.02 |
1.13 |
0.29 |
| Psychotic and bipolar disorder |
10.86 |
3.17 |
18.55 |
3.91 |
0.006 |
| Only psychotic disorder |
-1.50 |
-7.07 |
4.07 |
2.83 |
0.60 |
| Only bipolar disorder |
-1.37 |
-5.06 |
2.32 |
1.88 |
0.47 |
| PTSD |
-3.64 |
-6.15 |
-1.12 |
1.28 |
0.005 |
| ASD |
-0.28 |
-4.63 |
4.07 |
2.21 |
0.90 |
| ADHD |
5.40 |
-1.07 |
11.87 |
3.29 |
0.10 |
| Personality disorder |
-1.20 |
-4.46 |
2.05 |
1.66 |
0.47 |
| Female |
-1.73 |
-4.84 |
1.38 |
1.58 |
0.27 |
| Non-binary/Self-defined |
-1.47 |
-7.49 |
4.56 |
3.07 |
0.63 |
| Age |
29.85 |
-91.87 |
151.56 |
61.92 |
0.63 |
| Age^2 |
-138.78 |
-261.27 |
-16.30 |
62.31 |
0.03 |
| Mixed or multiple ethnic origins |
2.62 |
-4.05 |
9.28 |
3.39 |
0.44 |
| Asian or Asian British |
-23.04 |
-37.80 |
-8.29 |
7.51 |
0.002 |
| African or African British |
17.70 |
-3.19 |
38.59 |
10.63 |
0.10 |
| Other ethnicity |
-1.34 |
-9.89 |
7.21 |
4.35 |
0.76 |
| Key worker |
1.15 |
-1.05 |
3.36 |
1.12 |
0.30 |
| Time difference: Lockdown to baseline |
0.51 |
-0.24 |
1.26 |
0.38 |
0.18 |
| 436 |
0.02 |
0.00 |
1.20 |
0.31 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
9.60 |
-1.32 |
20.52 |
5.56 |
0.08 |
| ocir.sum_score_prepan |
0.65 |
0.58 |
0.71 |
0.03 |
3.49e-61 |
| Anxiety disorders |
-11.49 |
-23.36 |
0.38 |
6.04 |
0.06 |
| Eating disorders |
-9.29 |
-26.42 |
7.84 |
8.71 |
0.29 |
| OCDs |
-9.11 |
-21.35 |
3.13 |
6.23 |
0.14 |
| PTSD |
-20.88 |
-38.02 |
-3.73 |
8.72 |
0.02 |
| Depressive disorders |
-8.32 |
-19.20 |
2.56 |
5.54 |
0.13 |
| Bipolar disorders |
-5.59 |
-16.81 |
5.63 |
5.71 |
0.33 |
| 436 |
0.49 |
0.49 |
59.80 |
1.44e-59 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
5.70 |
-1.50 |
12.89 |
3.66 |
0.12 |
| ocir.sum_score_prepan |
0.64 |
0.57 |
0.71 |
0.04 |
1.22e-53 |
| Depressive and anxiety disorder |
-4.17 |
-11.31 |
2.97 |
3.63 |
0.25 |
| Only depressive disorder |
-5.37 |
-13.21 |
2.46 |
3.99 |
0.18 |
| Only anxiety disorder |
-8.62 |
-16.46 |
-0.78 |
3.99 |
0.03 |
| Eating disorders |
0.48 |
-1.94 |
2.89 |
1.23 |
0.70 |
| OCDs |
2.28 |
0.17 |
4.39 |
1.07 |
0.03 |
| Psychotic and bipolar disorder |
11.83 |
4.99 |
18.67 |
3.48 |
7.37e-04 |
| Only psychotic disorder |
0.58 |
-4.40 |
5.55 |
2.53 |
0.82 |
| Only bipolar disorder |
0.87 |
-2.43 |
4.17 |
1.68 |
0.61 |
| PTSD |
-2.65 |
-4.87 |
-0.43 |
1.13 |
0.02 |
| ASD |
0.22 |
-3.66 |
4.10 |
1.97 |
0.91 |
| ADHD |
4.02 |
-1.82 |
9.85 |
2.97 |
0.18 |
| Personality disorder |
-0.69 |
-3.62 |
2.25 |
1.49 |
0.65 |
| 1786 |
0.03 |
0.03 |
10.03 |
6.36e-11 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
14.34 |
-1.04 |
29.71 |
7.82 |
0.07 |
| ocir.sum_score_prepan |
0.66 |
0.59 |
0.73 |
0.03 |
4.03e-59 |
| Anxiety disorders |
-15.86 |
-30.44 |
-1.27 |
7.42 |
0.03 |
| Eating disorders |
-13.66 |
-32.79 |
5.48 |
9.73 |
0.16 |
| OCDs |
-14.11 |
-28.95 |
0.73 |
7.55 |
0.06 |
| PTSD |
-25.47 |
-44.67 |
-6.27 |
9.77 |
0.009 |
| Depressive disorders |
-13.35 |
-27.11 |
0.42 |
7.00 |
0.06 |
| Bipolar disorders |
-10.79 |
-24.80 |
3.22 |
7.13 |
0.13 |
| Female |
-1.78 |
-4.57 |
1.01 |
1.42 |
0.21 |
| Non-binary/Self-defined |
-1.60 |
-6.96 |
3.77 |
2.73 |
0.56 |
| age_category_collapsed_reordered16-18 |
-6.17 |
-12.49 |
0.15 |
3.21 |
0.06 |
| 19-25 years |
-1.43 |
-4.15 |
1.30 |
1.39 |
0.30 |
| 36-45 years |
0.16 |
-2.63 |
2.96 |
1.42 |
0.91 |
| 46-55 years |
0.59 |
-2.12 |
3.31 |
1.38 |
0.67 |
| 56-65 years |
-2.25 |
-5.61 |
1.11 |
1.71 |
0.19 |
| 66-70 years |
-3.11 |
-9.08 |
2.86 |
3.04 |
0.31 |
| 71-75 years |
-3.87 |
-14.88 |
7.13 |
5.60 |
0.49 |
| Mixed or multiple ethnic origins |
0.73 |
-5.31 |
6.77 |
3.07 |
0.81 |
| Asian or Asian British |
-16.33 |
-29.77 |
-2.89 |
6.84 |
0.02 |
| African or African British |
21.98 |
2.34 |
41.61 |
9.99 |
0.03 |
| Other ethnicity |
1.08 |
-6.75 |
8.92 |
3.99 |
0.79 |
| Key worker |
0.18 |
-1.81 |
2.17 |
1.01 |
0.86 |
| Time difference: Lockdown to baseline |
0.29 |
-0.40 |
0.99 |
0.35 |
0.40 |
| 1786 |
0.03 |
0.03 |
10.03 |
6.36e-11 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.70 |
-5.19 |
14.59 |
5.03 |
0.35 |
| ocir.sum_score_prepan |
0.64 |
0.57 |
0.72 |
0.04 |
7.34e-51 |
| Depressive and anxiety disorder |
-5.06 |
-12.99 |
2.87 |
4.03 |
0.21 |
| Only depressive disorder |
-6.01 |
-14.57 |
2.55 |
4.35 |
0.17 |
| Only anxiety disorder |
-8.84 |
-17.42 |
-0.25 |
4.37 |
0.04 |
| Eating disorders |
0.86 |
-1.61 |
3.33 |
1.26 |
0.49 |
| OCDs |
2.41 |
0.26 |
4.57 |
1.10 |
0.03 |
| Psychotic and bipolar disorder |
10.72 |
3.74 |
17.70 |
3.55 |
0.003 |
| Only psychotic disorder |
0.10 |
-5.02 |
5.21 |
2.60 |
0.97 |
| Only bipolar disorder |
0.61 |
-2.78 |
3.99 |
1.72 |
0.73 |
| PTSD |
-2.34 |
-4.64 |
-0.04 |
1.17 |
0.05 |
| ASD |
-0.19 |
-4.14 |
3.76 |
2.01 |
0.92 |
| ADHD |
3.54 |
-2.37 |
9.45 |
3.01 |
0.24 |
| Personality disorder |
-0.21 |
-3.17 |
2.76 |
1.51 |
0.89 |
| Female |
-1.56 |
-4.39 |
1.27 |
1.44 |
0.28 |
| Non-binary/Self-defined |
-0.84 |
-6.34 |
4.66 |
2.80 |
0.77 |
| age_category_collapsed_reordered16-18 |
-5.12 |
-11.32 |
1.09 |
3.16 |
0.11 |
| 19-25 years |
-1.40 |
-4.13 |
1.32 |
1.39 |
0.31 |
| 36-45 years |
-0.13 |
-2.92 |
2.66 |
1.42 |
0.93 |
| 46-55 years |
1.33 |
-1.42 |
4.08 |
1.40 |
0.34 |
| 56-65 years |
-1.99 |
-5.38 |
1.39 |
1.72 |
0.25 |
| 66-70 years |
-2.86 |
-8.84 |
3.11 |
3.04 |
0.35 |
| 71-75 years |
-0.05 |
-9.77 |
9.67 |
4.94 |
0.99 |
| Mixed or multiple ethnic origins |
-0.02 |
-6.10 |
6.06 |
3.09 |
1.00 |
| Asian or Asian British |
-12.62 |
-26.19 |
0.94 |
6.90 |
0.07 |
| African or African British |
22.55 |
3.03 |
42.06 |
9.93 |
0.02 |
| Other ethnicity |
0.67 |
-7.12 |
8.47 |
3.97 |
0.87 |
| Key worker |
0.00 |
-2.01 |
2.01 |
1.02 |
1.00 |
| Time difference: Lockdown to baseline |
0.47 |
-0.21 |
1.15 |
0.35 |
0.17 |
| 1786 |
0.03 |
0.03 |
10.03 |
6.36e-11 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
12.31 |
-2.62 |
27.24 |
7.59 |
0.11 |
| ocir.sum_score_prepan |
0.66 |
0.60 |
0.73 |
0.03 |
9.77e-61 |
| Anxiety disorders |
-14.89 |
-29.15 |
-0.63 |
7.25 |
0.04 |
| Eating disorders |
-11.62 |
-30.39 |
7.15 |
9.55 |
0.22 |
| OCDs |
-12.41 |
-26.82 |
2.00 |
7.33 |
0.09 |
| PTSD |
-24.34 |
-43.16 |
-5.53 |
9.57 |
0.01 |
| Depressive disorders |
-11.88 |
-25.27 |
1.52 |
6.82 |
0.08 |
| Bipolar disorders |
-9.39 |
-23.07 |
4.28 |
6.96 |
0.18 |
| Female |
-1.75 |
-4.51 |
1.02 |
1.41 |
0.22 |
| Non-binary/Self-defined |
-1.46 |
-6.78 |
3.86 |
2.71 |
0.59 |
| Age |
-34.22 |
-143.84 |
75.40 |
55.77 |
0.54 |
| Age^2 |
-146.19 |
-258.05 |
-34.33 |
56.90 |
0.01 |
| Mixed or multiple ethnic origins |
0.79 |
-5.21 |
6.79 |
3.05 |
0.80 |
| Asian or Asian British |
-16.72 |
-30.09 |
-3.36 |
6.80 |
0.01 |
| African or African British |
22.89 |
3.86 |
41.91 |
9.68 |
0.02 |
| Other ethnicity |
0.88 |
-6.89 |
8.66 |
3.95 |
0.82 |
| Key worker |
0.09 |
-1.90 |
2.07 |
1.01 |
0.93 |
| Time difference: Lockdown to baseline |
0.28 |
-0.40 |
0.97 |
0.35 |
0.42 |
| 1786 |
0.03 |
0.03 |
10.03 |
6.36e-11 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
4.86 |
-4.65 |
14.37 |
4.84 |
0.32 |
| ocir.sum_score_prepan |
0.65 |
0.58 |
0.72 |
0.04 |
5.32e-53 |
| Depressive and anxiety disorder |
-5.20 |
-12.95 |
2.55 |
3.94 |
0.19 |
| Only depressive disorder |
-6.59 |
-14.96 |
1.78 |
4.26 |
0.12 |
| Only anxiety disorder |
-9.27 |
-17.69 |
-0.86 |
4.28 |
0.03 |
| Eating disorders |
0.72 |
-1.74 |
3.18 |
1.25 |
0.57 |
| OCDs |
2.22 |
0.09 |
4.35 |
1.08 |
0.04 |
| Psychotic and bipolar disorder |
10.57 |
3.62 |
17.52 |
3.54 |
0.003 |
| Only psychotic disorder |
-0.11 |
-5.16 |
4.93 |
2.57 |
0.97 |
| Only bipolar disorder |
0.67 |
-2.69 |
4.03 |
1.71 |
0.69 |
| PTSD |
-2.54 |
-4.83 |
-0.26 |
1.16 |
0.03 |
| ASD |
0.09 |
-3.84 |
4.02 |
2.00 |
0.96 |
| ADHD |
3.40 |
-2.46 |
9.26 |
2.98 |
0.26 |
| Personality disorder |
-0.42 |
-3.37 |
2.53 |
1.50 |
0.78 |
| Female |
-1.58 |
-4.39 |
1.23 |
1.43 |
0.27 |
| Non-binary/Self-defined |
-0.71 |
-6.16 |
4.74 |
2.77 |
0.80 |
| Age |
-2.43 |
-112.61 |
107.75 |
56.05 |
0.97 |
| Age^2 |
-125.54 |
-236.26 |
-14.82 |
56.32 |
0.03 |
| Mixed or multiple ethnic origins |
0.16 |
-5.88 |
6.21 |
3.07 |
0.96 |
| Asian or Asian British |
-13.23 |
-26.71 |
0.25 |
6.86 |
0.05 |
| African or African British |
22.25 |
3.35 |
41.15 |
9.62 |
0.02 |
| Other ethnicity |
0.47 |
-7.27 |
8.21 |
3.94 |
0.90 |
| Key worker |
-0.03 |
-2.03 |
1.98 |
1.02 |
0.98 |
| Time difference: Lockdown to baseline |
0.43 |
-0.25 |
1.10 |
0.34 |
0.21 |
| 1786 |
0.03 |
0.03 |
10.03 |
6.36e-11 |
6 |
OCIR retro
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
3.87 |
3.16 |
4.58 |
0.36 |
1.93e-26 |
| Anxiety disorders |
-0.87 |
-2.14 |
0.41 |
0.65 |
0.18 |
| Eating disorders |
-3.63 |
-7.18 |
-0.07 |
1.81 |
0.05 |
| OCDs |
-1.87 |
-4.22 |
0.48 |
1.20 |
0.12 |
| PTSD |
-0.55 |
-3.15 |
2.06 |
1.33 |
0.68 |
| Depressive disorders |
-3.95 |
-4.74 |
-3.17 |
0.40 |
1.59e-22 |
| Bipolar disorders |
-3.57 |
-4.89 |
-2.24 |
0.68 |
1.40e-07 |
| 4329 |
0.03 |
0.03 |
19.83 |
5.68e-23 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
3.83 |
3.19 |
4.47 |
0.33 |
4.16e-31 |
| Depressive and anxiety disorder |
-4.38 |
-5.16 |
-3.60 |
0.40 |
6.38e-28 |
| Only depressive disorder |
-2.11 |
-3.19 |
-1.03 |
0.55 |
1.37e-04 |
| Only anxiety disorder |
-1.42 |
-2.54 |
-0.31 |
0.57 |
0.01 |
| Eating disorders |
-0.25 |
-1.18 |
0.68 |
0.47 |
0.60 |
| OCDs |
0.30 |
-0.50 |
1.11 |
0.41 |
0.46 |
| Psychotic and bipolar disorder |
2.22 |
0.03 |
4.40 |
1.11 |
0.05 |
| Only psychotic disorder |
0.58 |
-1.38 |
2.53 |
1.00 |
0.56 |
| Only bipolar disorder |
-0.55 |
-1.93 |
0.82 |
0.70 |
0.43 |
| PTSD |
0.21 |
-0.58 |
1.00 |
0.40 |
0.60 |
| ASD |
1.82 |
0.35 |
3.30 |
0.75 |
0.02 |
| ADHD |
2.21 |
0.12 |
4.29 |
1.06 |
0.04 |
| Personality disorder |
-0.61 |
-1.69 |
0.47 |
0.55 |
0.27 |
| 4329 |
0.03 |
0.03 |
19.83 |
5.68e-23 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
11.33 |
9.98 |
12.69 |
0.69 |
1.48e-58 |
| Anxiety disorders |
-0.24 |
-1.45 |
0.97 |
0.62 |
0.70 |
| Eating disorders |
-2.11 |
-5.41 |
1.18 |
1.68 |
0.21 |
| OCDs |
-0.32 |
-2.52 |
1.89 |
1.13 |
0.78 |
| PTSD |
-0.45 |
-2.91 |
2.01 |
1.25 |
0.72 |
| Depressive disorders |
-2.12 |
-2.90 |
-1.35 |
0.40 |
8.11e-08 |
| Bipolar disorders |
-1.61 |
-2.87 |
-0.35 |
0.64 |
0.01 |
| Female |
0.19 |
-0.57 |
0.95 |
0.39 |
0.62 |
| Non-binary/Self-defined |
-0.14 |
-2.20 |
1.91 |
1.05 |
0.89 |
| age_category_collapsed_reordered16-18 |
4.14 |
2.72 |
5.56 |
0.72 |
1.14e-08 |
| 19-25 years |
-0.54 |
-1.57 |
0.48 |
0.52 |
0.30 |
| 36-45 years |
0.26 |
-0.68 |
1.19 |
0.48 |
0.59 |
| 46-55 years |
0.37 |
-0.50 |
1.23 |
0.44 |
0.40 |
| 56-65 years |
1.96 |
1.09 |
2.83 |
0.44 |
1.05e-05 |
| 66-70 years |
2.12 |
0.81 |
3.43 |
0.67 |
0.002 |
| 71-75 years |
2.71 |
1.11 |
4.31 |
0.82 |
9.01e-04 |
| 76+ years |
-0.03 |
-3.38 |
3.32 |
1.71 |
0.99 |
| Mixed or multiple ethnic origins |
1.54 |
-0.25 |
3.33 |
0.91 |
0.09 |
| Asian or Asian British |
2.65 |
-0.05 |
5.36 |
1.38 |
0.05 |
| African or African British |
0.77 |
-3.58 |
5.12 |
2.22 |
0.73 |
| Other ethnicity |
-0.64 |
-3.24 |
1.96 |
1.33 |
0.63 |
| Time difference: Lockdown to baseline |
-1.65 |
-1.77 |
-1.52 |
0.06 |
6.65e-134 |
| 4329 |
0.03 |
0.03 |
19.83 |
5.68e-23 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
11.18 |
9.84 |
12.53 |
0.69 |
3.87e-58 |
| Depressive and anxiety disorder |
-2.52 |
-3.28 |
-1.75 |
0.39 |
1.10e-10 |
| Only depressive disorder |
-1.45 |
-2.49 |
-0.42 |
0.53 |
0.006 |
| Only anxiety disorder |
-0.73 |
-1.79 |
0.33 |
0.54 |
0.18 |
| Eating disorders |
-0.09 |
-0.96 |
0.77 |
0.44 |
0.83 |
| OCDs |
0.38 |
-0.38 |
1.13 |
0.38 |
0.33 |
| Psychotic and bipolar disorder |
2.27 |
0.23 |
4.30 |
1.04 |
0.03 |
| Only psychotic disorder |
0.30 |
-1.51 |
2.12 |
0.93 |
0.74 |
| Only bipolar disorder |
-0.31 |
-1.61 |
0.98 |
0.66 |
0.64 |
| PTSD |
0.16 |
-0.59 |
0.91 |
0.38 |
0.68 |
| ASD |
1.01 |
-0.40 |
2.41 |
0.72 |
0.16 |
| ADHD |
1.67 |
-0.26 |
3.61 |
0.99 |
0.09 |
| Personality disorder |
-0.24 |
-1.25 |
0.77 |
0.52 |
0.63 |
| Female |
0.30 |
-0.45 |
1.06 |
0.39 |
0.43 |
| Non-binary/Self-defined |
-0.66 |
-2.72 |
1.40 |
1.05 |
0.53 |
| age_category_collapsed_reordered16-18 |
4.01 |
2.64 |
5.39 |
0.70 |
1.07e-08 |
| 19-25 years |
-0.48 |
-1.50 |
0.54 |
0.52 |
0.35 |
| 36-45 years |
0.22 |
-0.71 |
1.15 |
0.47 |
0.64 |
| 46-55 years |
0.30 |
-0.56 |
1.17 |
0.44 |
0.50 |
| 56-65 years |
1.86 |
0.98 |
2.73 |
0.45 |
3.55e-05 |
| 66-70 years |
2.17 |
0.84 |
3.50 |
0.68 |
0.001 |
| 71-75 years |
2.14 |
0.52 |
3.76 |
0.83 |
0.010 |
| 76+ years |
0.02 |
-3.32 |
3.37 |
1.71 |
0.99 |
| Mixed or multiple ethnic origins |
1.35 |
-0.44 |
3.14 |
0.91 |
0.14 |
| Asian or Asian British |
2.32 |
-0.28 |
4.92 |
1.33 |
0.08 |
| African or African British |
0.91 |
-3.41 |
5.24 |
2.21 |
0.68 |
| Other ethnicity |
-0.67 |
-3.28 |
1.95 |
1.33 |
0.62 |
| Key worker |
-0.08 |
-0.65 |
0.50 |
0.29 |
0.80 |
| Time difference: Lockdown to baseline |
-1.61 |
-1.73 |
-1.48 |
0.06 |
8.63e-132 |
| 4329 |
0.03 |
0.03 |
19.83 |
5.68e-23 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.61 |
-5.25 |
-1.98 |
0.83 |
1.55e-05 |
| Anxiety disorders |
-0.51 |
-2.15 |
1.14 |
0.84 |
0.55 |
| Eating disorders |
1.23 |
-2.21 |
4.66 |
1.75 |
0.48 |
| OCDs |
-1.05 |
-3.73 |
1.63 |
1.37 |
0.44 |
| PTSD |
-2.80 |
-6.26 |
0.65 |
1.76 |
0.11 |
| Depressive disorders |
-0.86 |
-1.92 |
0.20 |
0.54 |
0.11 |
| Bipolar disorders |
-1.17 |
-2.64 |
0.29 |
0.75 |
0.12 |
| Female |
-0.59 |
-1.40 |
0.21 |
0.41 |
0.15 |
| Non-binary/Self-defined |
-0.72 |
-2.80 |
1.36 |
1.06 |
0.50 |
| Age |
74.54 |
31.90 |
117.17 |
21.74 |
6.19e-04 |
| Age^2 |
-24.16 |
-65.99 |
17.67 |
21.33 |
0.26 |
| Mixed or multiple ethnic origins |
2.68 |
0.82 |
4.54 |
0.95 |
0.005 |
| Asian or Asian British |
-0.83 |
-4.61 |
2.94 |
1.92 |
0.67 |
| African or African British |
-0.67 |
-6.20 |
4.86 |
2.82 |
0.81 |
| Other ethnicity |
1.15 |
-1.58 |
3.88 |
1.39 |
0.41 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.19 |
0.12 |
0.08 |
0.67 |
| 2307 |
0.00 |
0.00 |
1.72 |
0.11 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.62 |
-5.23 |
-2.02 |
0.82 |
9.55e-06 |
| Depressive and anxiety disorder |
-0.65 |
-1.64 |
0.35 |
0.51 |
0.21 |
| Only depressive disorder |
-1.15 |
-2.48 |
0.19 |
0.68 |
0.09 |
| Only anxiety disorder |
-1.06 |
-2.49 |
0.36 |
0.73 |
0.14 |
| Eating disorders |
0.46 |
-0.42 |
1.34 |
0.45 |
0.30 |
| OCDs |
-0.27 |
-1.04 |
0.50 |
0.39 |
0.50 |
| Psychotic and bipolar disorder |
0.49 |
-1.77 |
2.74 |
1.15 |
0.67 |
| Only psychotic disorder |
0.11 |
-1.70 |
1.92 |
0.92 |
0.91 |
| Only bipolar disorder |
-0.27 |
-1.54 |
1.01 |
0.65 |
0.68 |
| PTSD |
-0.60 |
-1.37 |
0.17 |
0.39 |
0.13 |
| ASD |
0.14 |
-1.50 |
1.78 |
0.84 |
0.87 |
| ADHD |
2.02 |
-0.35 |
4.38 |
1.20 |
0.09 |
| Personality disorder |
-0.90 |
-1.91 |
0.12 |
0.52 |
0.08 |
| Female |
-0.54 |
-1.34 |
0.25 |
0.41 |
0.18 |
| Non-binary/Self-defined |
-0.95 |
-3.05 |
1.16 |
1.07 |
0.38 |
| Age |
75.67 |
31.94 |
119.39 |
22.30 |
7.02e-04 |
| Age^2 |
-24.24 |
-66.89 |
18.42 |
21.75 |
0.27 |
| Mixed or multiple ethnic origins |
2.69 |
0.82 |
4.56 |
0.95 |
0.005 |
| Asian or Asian British |
-1.51 |
-5.14 |
2.13 |
1.85 |
0.42 |
| African or African British |
-0.56 |
-6.07 |
4.96 |
2.81 |
0.84 |
| Other ethnicity |
1.47 |
-1.31 |
4.24 |
1.42 |
0.30 |
| Key worker |
0.11 |
-0.50 |
0.72 |
0.31 |
0.73 |
| Time difference: Lockdown to baseline |
-0.04 |
-0.19 |
0.12 |
0.08 |
0.64 |
| 2307 |
0.00 |
0.00 |
1.72 |
0.11 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
6.44 |
5.74 |
7.13 |
0.36 |
1.09e-70 |
| ocir.sum_score_retro |
0.73 |
0.71 |
0.75 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.10 |
-1.30 |
1.10 |
0.61 |
0.87 |
| Eating disorders |
-1.54 |
-4.88 |
1.80 |
1.70 |
0.37 |
| OCDs |
1.47 |
-0.76 |
3.69 |
1.13 |
0.20 |
| PTSD |
1.43 |
-1.02 |
3.88 |
1.25 |
0.25 |
| Depressive disorders |
-1.50 |
-2.27 |
-0.73 |
0.39 |
1.33e-04 |
| Bipolar disorders |
0.55 |
-0.74 |
1.84 |
0.66 |
0.40 |
| 4329 |
0.52 |
0.52 |
665.07 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
6.91 |
6.26 |
7.55 |
0.33 |
1.85e-93 |
| ocir.sum_score_retro |
0.70 |
0.68 |
0.73 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-2.55 |
-3.29 |
-1.81 |
0.38 |
1.67e-11 |
| Only depressive disorder |
-1.71 |
-2.72 |
-0.69 |
0.52 |
9.57e-04 |
| Only anxiety disorder |
-0.70 |
-1.74 |
0.35 |
0.53 |
0.19 |
| Eating disorders |
-0.09 |
-0.95 |
0.78 |
0.44 |
0.84 |
| OCDs |
2.46 |
1.69 |
3.23 |
0.39 |
4.48e-10 |
| Psychotic and bipolar disorder |
3.47 |
1.43 |
5.51 |
1.04 |
8.69e-04 |
| Only psychotic disorder |
1.72 |
-0.11 |
3.55 |
0.93 |
0.07 |
| Only bipolar disorder |
0.59 |
-0.69 |
1.88 |
0.66 |
0.37 |
| PTSD |
0.78 |
0.04 |
1.52 |
0.38 |
0.04 |
| ASD |
3.70 |
2.31 |
5.08 |
0.71 |
1.73e-07 |
| ADHD |
2.01 |
0.06 |
3.95 |
0.99 |
0.04 |
| Personality disorder |
0.67 |
-0.34 |
1.69 |
0.52 |
0.19 |
| 5094 |
0.06 |
0.06 |
51.24 |
1.63e-61 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
12.90 |
11.58 |
14.22 |
0.67 |
1.24e-78 |
| ocir.sum_score_retro |
0.77 |
0.75 |
0.79 |
0.01 |
0.00e+00 |
| Anxiety disorders |
0.15 |
-1.00 |
1.30 |
0.59 |
0.79 |
| Eating disorders |
-0.79 |
-3.92 |
2.34 |
1.60 |
0.62 |
| OCDs |
1.71 |
-0.41 |
3.83 |
1.08 |
0.11 |
| PTSD |
1.12 |
-1.24 |
3.48 |
1.20 |
0.35 |
| Depressive disorders |
-0.46 |
-1.21 |
0.30 |
0.39 |
0.24 |
| Bipolar disorders |
1.41 |
0.17 |
2.65 |
0.63 |
0.03 |
| Female |
0.14 |
-0.58 |
0.87 |
0.37 |
0.69 |
| Non-binary/Self-defined |
0.56 |
-1.40 |
2.51 |
1.00 |
0.58 |
| age_category_collapsed_reordered16-18 |
4.78 |
3.42 |
6.14 |
0.69 |
6.34e-12 |
| 19-25 years |
-0.18 |
-1.16 |
0.79 |
0.50 |
0.71 |
| 36-45 years |
-0.02 |
-0.91 |
0.86 |
0.45 |
0.96 |
| 46-55 years |
0.10 |
-0.73 |
0.92 |
0.42 |
0.82 |
| 56-65 years |
1.10 |
0.27 |
1.94 |
0.43 |
0.010 |
| 66-70 years |
1.05 |
-0.22 |
2.32 |
0.65 |
0.10 |
| 71-75 years |
0.83 |
-0.71 |
2.37 |
0.79 |
0.29 |
| 76+ years |
-1.03 |
-4.26 |
2.21 |
1.65 |
0.53 |
| Mixed or multiple ethnic origins |
1.45 |
-0.26 |
3.17 |
0.87 |
0.10 |
| Asian or Asian British |
3.38 |
0.81 |
5.95 |
1.31 |
0.010 |
| African or African British |
1.02 |
-3.11 |
5.15 |
2.11 |
0.63 |
| Other ethnicity |
0.19 |
-2.30 |
2.69 |
1.27 |
0.88 |
| Key worker |
-0.50 |
-1.05 |
0.05 |
0.28 |
0.07 |
| Time difference: Lockdown to baseline |
-1.40 |
-1.52 |
-1.28 |
0.06 |
1.25e-105 |
| 5094 |
0.06 |
0.06 |
51.24 |
1.63e-61 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
12.78 |
11.50 |
14.06 |
0.65 |
8.31e-82 |
| ocir.sum_score_retro |
0.75 |
0.72 |
0.77 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-1.21 |
-1.94 |
-0.48 |
0.37 |
0.001 |
| Only depressive disorder |
-1.02 |
-2.00 |
-0.03 |
0.50 |
0.04 |
| Only anxiety disorder |
-0.29 |
-1.29 |
0.72 |
0.51 |
0.57 |
| Eating disorders |
-0.05 |
-0.87 |
0.78 |
0.42 |
0.91 |
| OCDs |
2.11 |
1.38 |
2.84 |
0.37 |
1.56e-08 |
| Psychotic and bipolar disorder |
3.34 |
1.41 |
5.27 |
0.98 |
6.97e-04 |
| Only psychotic disorder |
1.23 |
-0.50 |
2.95 |
0.88 |
0.16 |
| Only bipolar disorder |
0.58 |
-0.65 |
1.81 |
0.63 |
0.35 |
| PTSD |
0.72 |
0.01 |
1.43 |
0.36 |
0.05 |
| ASD |
2.48 |
1.14 |
3.81 |
0.68 |
2.80e-04 |
| ADHD |
1.46 |
-0.37 |
3.29 |
0.93 |
0.12 |
| Personality disorder |
0.74 |
-0.22 |
1.70 |
0.49 |
0.13 |
| Female |
0.17 |
-0.55 |
0.88 |
0.37 |
0.65 |
| Non-binary/Self-defined |
-0.52 |
-2.47 |
1.43 |
0.99 |
0.60 |
| age_category_collapsed_reordered16-18 |
5.02 |
3.72 |
6.32 |
0.66 |
5.04e-14 |
| 19-25 years |
0.04 |
-0.92 |
1.00 |
0.49 |
0.93 |
| 36-45 years |
0.11 |
-0.77 |
0.98 |
0.45 |
0.81 |
| 46-55 years |
0.27 |
-0.55 |
1.08 |
0.42 |
0.52 |
| 56-65 years |
1.33 |
0.49 |
2.16 |
0.42 |
0.002 |
| 66-70 years |
1.55 |
0.29 |
2.81 |
0.64 |
0.02 |
| 71-75 years |
1.18 |
-0.35 |
2.71 |
0.78 |
0.13 |
| 76+ years |
-0.81 |
-3.98 |
2.36 |
1.62 |
0.62 |
| Mixed or multiple ethnic origins |
1.10 |
-0.60 |
2.79 |
0.86 |
0.20 |
| Asian or Asian British |
3.38 |
0.92 |
5.85 |
1.26 |
0.007 |
| African or African British |
1.35 |
-2.75 |
5.44 |
2.09 |
0.52 |
| Other ethnicity |
-0.05 |
-2.53 |
2.42 |
1.26 |
0.97 |
| Key worker |
-0.39 |
-0.94 |
0.15 |
0.28 |
0.16 |
| Time difference: Lockdown to baseline |
-1.35 |
-1.47 |
-1.23 |
0.06 |
7.16e-102 |
| 5094 |
0.06 |
0.06 |
51.24 |
1.63e-61 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.38 |
-2.95 |
0.20 |
0.80 |
0.09 |
| ocir.sum_score_retro |
0.81 |
0.78 |
0.83 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.39 |
-1.94 |
1.15 |
0.79 |
0.62 |
| Eating disorders |
2.53 |
-0.68 |
5.75 |
1.64 |
0.12 |
| OCDs |
1.25 |
-1.27 |
3.78 |
1.29 |
0.33 |
| PTSD |
-0.42 |
-3.66 |
2.82 |
1.65 |
0.80 |
| Depressive disorders |
0.68 |
-0.33 |
1.70 |
0.52 |
0.19 |
| Bipolar disorders |
1.65 |
0.24 |
3.06 |
0.72 |
0.02 |
| Female |
-0.52 |
-1.27 |
0.23 |
0.38 |
0.17 |
| Non-binary/Self-defined |
-0.02 |
-1.97 |
1.93 |
0.99 |
0.98 |
| Age |
21.02 |
-19.75 |
61.79 |
20.79 |
0.31 |
| Age^2 |
-30.35 |
-70.33 |
9.63 |
20.39 |
0.14 |
| Mixed or multiple ethnic origins |
2.54 |
0.77 |
4.31 |
0.90 |
0.005 |
| Asian or Asian British |
1.26 |
-2.28 |
4.80 |
1.80 |
0.48 |
| African or African British |
0.31 |
-4.87 |
5.49 |
2.64 |
0.91 |
| Other ethnicity |
1.49 |
-1.11 |
4.10 |
1.33 |
0.26 |
| Key worker |
-0.34 |
-0.91 |
0.23 |
0.29 |
0.24 |
| Time difference: Lockdown to baseline |
0.02 |
-0.13 |
0.17 |
0.08 |
0.80 |
| 2313 |
0.07 |
0.07 |
30.36 |
3.08e-35 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-1.12 |
-2.64 |
0.40 |
0.78 |
0.15 |
| ocir.sum_score_retro |
0.79 |
0.77 |
0.82 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.43 |
-0.51 |
1.38 |
0.48 |
0.37 |
| Only depressive disorder |
-0.40 |
-1.65 |
0.85 |
0.64 |
0.53 |
| Only anxiety disorder |
-0.63 |
-1.96 |
0.70 |
0.68 |
0.35 |
| Eating disorders |
0.63 |
-0.19 |
1.45 |
0.42 |
0.13 |
| OCDs |
1.22 |
0.48 |
1.96 |
0.38 |
0.001 |
| Psychotic and bipolar disorder |
1.77 |
-0.34 |
3.88 |
1.07 |
0.10 |
| Only psychotic disorder |
0.75 |
-0.94 |
2.45 |
0.86 |
0.38 |
| Only bipolar disorder |
0.50 |
-0.69 |
1.70 |
0.61 |
0.41 |
| PTSD |
-0.03 |
-0.75 |
0.70 |
0.37 |
0.94 |
| ASD |
1.36 |
-0.17 |
2.90 |
0.78 |
0.08 |
| ADHD |
1.63 |
-0.58 |
3.84 |
1.13 |
0.15 |
| Personality disorder |
-0.11 |
-1.06 |
0.84 |
0.49 |
0.82 |
| Female |
-0.57 |
-1.31 |
0.18 |
0.38 |
0.14 |
| Non-binary/Self-defined |
-0.45 |
-2.42 |
1.51 |
1.00 |
0.65 |
| Age |
33.75 |
-7.36 |
74.86 |
20.96 |
0.11 |
| Age^2 |
-25.95 |
-65.80 |
13.90 |
20.32 |
0.20 |
| Mixed or multiple ethnic origins |
2.35 |
0.60 |
4.10 |
0.89 |
0.008 |
| Asian or Asian British |
0.66 |
-2.75 |
4.06 |
1.74 |
0.71 |
| African or African British |
0.66 |
-4.50 |
5.81 |
2.63 |
0.80 |
| Other ethnicity |
1.48 |
-1.11 |
4.07 |
1.32 |
0.26 |
| Key worker |
-0.21 |
-0.78 |
0.36 |
0.29 |
0.47 |
| Time difference: Lockdown to baseline |
0.02 |
-0.13 |
0.17 |
0.07 |
0.79 |
| 2313 |
0.07 |
0.07 |
30.36 |
3.08e-35 |
6 |
OCIR retro
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
-2.83 |
-6.91 |
1.24 |
2.08 |
0.17 |
| Anxiety disorders |
-2.22 |
-6.61 |
2.17 |
2.24 |
0.32 |
| Eating disorders |
-2.17 |
-8.88 |
4.55 |
3.42 |
0.53 |
| OCDs |
-3.29 |
-8.28 |
1.70 |
2.55 |
0.20 |
| PTSD |
-5.17 |
-11.06 |
0.73 |
3.01 |
0.09 |
| Depressive disorders |
-2.57 |
-6.66 |
1.52 |
2.09 |
0.22 |
| Bipolar disorders |
-2.70 |
-6.95 |
1.54 |
2.16 |
0.21 |
| 1746 |
0.00 |
0.00 |
0.58 |
0.75 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
-3.69 |
-6.52 |
-0.87 |
1.44 |
0.01 |
| Depressive and anxiety disorder |
-1.42 |
-4.27 |
1.44 |
1.46 |
0.33 |
| Only depressive disorder |
-1.99 |
-5.10 |
1.12 |
1.59 |
0.21 |
| Only anxiety disorder |
-2.05 |
-5.16 |
1.07 |
1.59 |
0.20 |
| Eating disorders |
0.14 |
-0.85 |
1.12 |
0.50 |
0.79 |
| OCDs |
-0.26 |
-1.11 |
0.58 |
0.43 |
0.54 |
| Psychotic and bipolar disorder |
0.76 |
-1.82 |
3.33 |
1.31 |
0.56 |
| Only psychotic disorder |
-0.04 |
-2.04 |
1.96 |
1.02 |
0.97 |
| Only bipolar disorder |
-0.26 |
-1.65 |
1.13 |
0.71 |
0.71 |
| PTSD |
-0.48 |
-1.31 |
0.36 |
0.43 |
0.26 |
| ASD |
-0.16 |
-1.97 |
1.65 |
0.92 |
0.86 |
| ADHD |
1.24 |
-1.46 |
3.93 |
1.37 |
0.37 |
| Personality disorder |
-0.75 |
-1.86 |
0.36 |
0.57 |
0.18 |
| 1746 |
0.00 |
0.00 |
0.58 |
0.75 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-3.18 |
-7.64 |
1.29 |
2.28 |
0.16 |
| Anxiety disorders |
-2.23 |
-6.61 |
2.15 |
2.23 |
0.32 |
| Eating disorders |
-2.00 |
-8.71 |
4.71 |
3.42 |
0.56 |
| OCDs |
-3.21 |
-8.19 |
1.76 |
2.54 |
0.21 |
| PTSD |
-5.21 |
-11.11 |
0.70 |
3.01 |
0.08 |
| Depressive disorders |
-2.76 |
-6.86 |
1.35 |
2.09 |
0.19 |
| Bipolar disorders |
-3.11 |
-7.36 |
1.14 |
2.17 |
0.15 |
| Female |
-0.78 |
-1.77 |
0.22 |
0.51 |
0.13 |
| Non-binary/Self-defined |
-0.68 |
-3.02 |
1.67 |
1.19 |
0.57 |
| age_category_collapsed_reordered16-18 |
0.28 |
-2.20 |
2.76 |
1.26 |
0.82 |
| 19-25 years |
-0.43 |
-1.59 |
0.73 |
0.59 |
0.47 |
| 36-45 years |
1.27 |
0.24 |
2.30 |
0.53 |
0.02 |
| 46-55 years |
0.97 |
-0.04 |
1.97 |
0.51 |
0.06 |
| 56-65 years |
1.05 |
-0.10 |
2.19 |
0.59 |
0.07 |
| 66-70 years |
2.35 |
0.05 |
4.65 |
1.17 |
0.04 |
| 71-75 years |
3.01 |
-0.30 |
6.33 |
1.69 |
0.08 |
| 76+ years |
0.63 |
-7.52 |
8.78 |
4.16 |
0.88 |
| Mixed or multiple ethnic origins |
2.51 |
0.35 |
4.66 |
1.10 |
0.02 |
| Asian or Asian British |
-1.11 |
-5.82 |
3.59 |
2.40 |
0.64 |
| African or African British |
-0.56 |
-6.87 |
5.75 |
3.22 |
0.86 |
| Other ethnicity |
1.49 |
-1.41 |
4.39 |
1.48 |
0.31 |
| Time difference: Lockdown to baseline |
0.07 |
-0.14 |
0.27 |
0.11 |
0.54 |
| 1746 |
0.00 |
0.00 |
0.58 |
0.75 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-4.07 |
-7.52 |
-0.62 |
1.76 |
0.02 |
| Depressive and anxiety disorder |
-1.64 |
-4.57 |
1.28 |
1.49 |
0.27 |
| Only depressive disorder |
-2.51 |
-5.69 |
0.66 |
1.62 |
0.12 |
| Only anxiety disorder |
-2.13 |
-5.29 |
1.03 |
1.61 |
0.19 |
| Eating disorders |
0.38 |
-0.61 |
1.37 |
0.51 |
0.45 |
| OCDs |
-0.16 |
-1.00 |
0.69 |
0.43 |
0.72 |
| Psychotic and bipolar disorder |
0.36 |
-2.21 |
2.94 |
1.31 |
0.78 |
| Only psychotic disorder |
-0.37 |
-2.38 |
1.63 |
1.02 |
0.71 |
| Only bipolar disorder |
-0.32 |
-1.73 |
1.08 |
0.72 |
0.65 |
| PTSD |
-0.46 |
-1.31 |
0.39 |
0.43 |
0.29 |
| ASD |
-0.06 |
-1.88 |
1.76 |
0.93 |
0.95 |
| ADHD |
1.36 |
-1.35 |
4.07 |
1.38 |
0.33 |
| Personality disorder |
-0.74 |
-1.85 |
0.38 |
0.57 |
0.19 |
| Female |
-0.77 |
-1.77 |
0.23 |
0.51 |
0.13 |
| Non-binary/Self-defined |
-0.83 |
-3.22 |
1.56 |
1.22 |
0.49 |
| age_category_collapsed_reordered16-18 |
0.50 |
-1.95 |
2.95 |
1.25 |
0.69 |
| 19-25 years |
-0.49 |
-1.65 |
0.68 |
0.59 |
0.41 |
| 36-45 years |
1.25 |
0.22 |
2.29 |
0.53 |
0.02 |
| 46-55 years |
0.96 |
-0.06 |
1.97 |
0.52 |
0.07 |
| 56-65 years |
1.09 |
-0.07 |
2.25 |
0.59 |
0.07 |
| 66-70 years |
2.31 |
0.02 |
4.61 |
1.17 |
0.05 |
| 71-75 years |
2.89 |
-0.36 |
6.15 |
1.66 |
0.08 |
| 76+ years |
0.91 |
-7.26 |
9.09 |
4.17 |
0.83 |
| Mixed or multiple ethnic origins |
2.46 |
0.28 |
4.64 |
1.11 |
0.03 |
| Asian or Asian British |
-1.13 |
-5.84 |
3.58 |
2.40 |
0.64 |
| African or African British |
-0.61 |
-6.92 |
5.69 |
3.21 |
0.85 |
| Other ethnicity |
1.78 |
-1.18 |
4.74 |
1.51 |
0.24 |
| Key worker |
0.11 |
-0.60 |
0.83 |
0.37 |
0.75 |
| Time difference: Lockdown to baseline |
0.07 |
-0.14 |
0.27 |
0.11 |
0.54 |
| 1746 |
0.00 |
0.00 |
0.58 |
0.75 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
1.61 |
-2.24 |
5.46 |
1.96 |
0.41 |
| ocir.sum_score_retro |
0.80 |
0.78 |
0.83 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-3.75 |
-7.86 |
0.35 |
2.09 |
0.07 |
| Eating disorders |
-2.66 |
-8.93 |
3.62 |
3.20 |
0.41 |
| OCDs |
-1.97 |
-6.64 |
2.69 |
2.38 |
0.41 |
| PTSD |
-4.33 |
-9.84 |
1.18 |
2.81 |
0.12 |
| Depressive disorders |
-2.63 |
-6.45 |
1.20 |
1.95 |
0.18 |
| Bipolar disorders |
-1.69 |
-5.66 |
2.27 |
2.02 |
0.40 |
| 1746 |
0.71 |
0.71 |
615.64 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
1.14 |
-1.55 |
3.83 |
1.37 |
0.41 |
| ocir.sum_score_retro |
0.78 |
0.76 |
0.81 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-2.11 |
-4.77 |
0.55 |
1.35 |
0.12 |
| Only depressive disorder |
-3.03 |
-5.93 |
-0.14 |
1.48 |
0.04 |
| Only anxiety disorder |
-3.28 |
-6.18 |
-0.39 |
1.48 |
0.03 |
| Eating disorders |
0.29 |
-0.63 |
1.21 |
0.47 |
0.53 |
| OCDs |
1.45 |
0.63 |
2.26 |
0.41 |
5.00e-04 |
| Psychotic and bipolar disorder |
1.84 |
-0.56 |
4.24 |
1.22 |
0.13 |
| Only psychotic disorder |
0.37 |
-1.49 |
2.23 |
0.95 |
0.70 |
| Only bipolar disorder |
0.39 |
-0.91 |
1.68 |
0.66 |
0.56 |
| PTSD |
0.06 |
-0.72 |
0.84 |
0.40 |
0.87 |
| ASD |
1.15 |
-0.54 |
2.84 |
0.86 |
0.18 |
| ADHD |
1.06 |
-1.45 |
3.57 |
1.28 |
0.41 |
| Personality disorder |
0.25 |
-0.78 |
1.29 |
0.53 |
0.63 |
| 1750 |
0.03 |
0.03 |
9.60 |
2.04e-10 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
1.67 |
-2.72 |
6.06 |
2.24 |
0.45 |
| ocir.sum_score_retro |
0.80 |
0.78 |
0.83 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-4.58 |
-8.83 |
-0.32 |
2.17 |
0.04 |
| Eating disorders |
-3.19 |
-9.57 |
3.19 |
3.25 |
0.33 |
| OCDs |
-2.77 |
-7.56 |
2.02 |
2.44 |
0.26 |
| PTSD |
-5.05 |
-10.68 |
0.59 |
2.87 |
0.08 |
| Depressive disorders |
-3.55 |
-7.56 |
0.46 |
2.04 |
0.08 |
| Bipolar disorders |
-2.64 |
-6.79 |
1.50 |
2.11 |
0.21 |
| Female |
-0.61 |
-1.54 |
0.33 |
0.48 |
0.20 |
| Non-binary/Self-defined |
-0.10 |
-2.30 |
2.09 |
1.12 |
0.93 |
| age_category_collapsed_reordered16-18 |
0.86 |
-1.46 |
3.18 |
1.18 |
0.47 |
| 19-25 years |
-0.21 |
-1.30 |
0.88 |
0.56 |
0.71 |
| 36-45 years |
0.86 |
-0.11 |
1.83 |
0.49 |
0.08 |
| 46-55 years |
0.89 |
-0.06 |
1.84 |
0.48 |
0.06 |
| 56-65 years |
0.55 |
-0.53 |
1.62 |
0.55 |
0.32 |
| 66-70 years |
1.32 |
-0.85 |
3.49 |
1.11 |
0.23 |
| 71-75 years |
0.86 |
-2.26 |
3.98 |
1.59 |
0.59 |
| 76+ years |
1.19 |
-6.42 |
8.80 |
3.88 |
0.76 |
| Mixed or multiple ethnic origins |
2.17 |
0.11 |
4.24 |
1.05 |
0.04 |
| Asian or Asian British |
1.63 |
-2.78 |
6.04 |
2.25 |
0.47 |
| African or African British |
0.82 |
-5.08 |
6.72 |
3.01 |
0.78 |
| Other ethnicity |
1.83 |
-0.93 |
4.60 |
1.41 |
0.19 |
| Key worker |
-0.39 |
-1.06 |
0.27 |
0.34 |
0.25 |
| Time difference: Lockdown to baseline |
0.13 |
-0.06 |
0.33 |
0.10 |
0.17 |
| 1750 |
0.03 |
0.03 |
9.60 |
2.04e-10 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
0.34 |
-2.91 |
3.60 |
1.66 |
0.84 |
| ocir.sum_score_retro |
0.78 |
0.76 |
0.81 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
-2.31 |
-5.03 |
0.41 |
1.39 |
0.10 |
| Only depressive disorder |
-3.37 |
-6.32 |
-0.41 |
1.51 |
0.03 |
| Only anxiety disorder |
-3.39 |
-6.33 |
-0.44 |
1.50 |
0.02 |
| Eating disorders |
0.48 |
-0.45 |
1.40 |
0.47 |
0.31 |
| OCDs |
1.52 |
0.70 |
2.33 |
0.42 |
2.77e-04 |
| Psychotic and bipolar disorder |
1.50 |
-0.90 |
3.90 |
1.22 |
0.22 |
| Only psychotic disorder |
0.06 |
-1.80 |
1.93 |
0.95 |
0.95 |
| Only bipolar disorder |
0.36 |
-0.95 |
1.67 |
0.67 |
0.59 |
| PTSD |
0.05 |
-0.75 |
0.84 |
0.40 |
0.91 |
| ASD |
1.08 |
-0.63 |
2.78 |
0.87 |
0.22 |
| ADHD |
1.05 |
-1.47 |
3.58 |
1.29 |
0.41 |
| Personality disorder |
0.21 |
-0.83 |
1.25 |
0.53 |
0.70 |
| Female |
-0.72 |
-1.65 |
0.21 |
0.48 |
0.13 |
| Non-binary/Self-defined |
-0.41 |
-2.63 |
1.81 |
1.13 |
0.72 |
| age_category_collapsed_reordered16-18 |
1.14 |
-1.14 |
3.42 |
1.16 |
0.33 |
| 19-25 years |
-0.16 |
-1.25 |
0.92 |
0.55 |
0.77 |
| 36-45 years |
0.91 |
-0.06 |
1.87 |
0.49 |
0.07 |
| 46-55 years |
1.03 |
0.09 |
1.98 |
0.48 |
0.03 |
| 56-65 years |
0.74 |
-0.34 |
1.82 |
0.55 |
0.18 |
| 66-70 years |
1.61 |
-0.53 |
3.74 |
1.09 |
0.14 |
| 71-75 years |
1.46 |
-1.57 |
4.50 |
1.55 |
0.34 |
| 76+ years |
0.82 |
-6.79 |
8.43 |
3.88 |
0.83 |
| Mixed or multiple ethnic origins |
1.94 |
-0.09 |
3.97 |
1.04 |
0.06 |
| Asian or Asian British |
1.47 |
-2.93 |
5.87 |
2.24 |
0.51 |
| African or African British |
1.25 |
-4.63 |
7.12 |
2.99 |
0.68 |
| Other ethnicity |
1.75 |
-1.01 |
4.51 |
1.41 |
0.21 |
| Key worker |
-0.24 |
-0.91 |
0.43 |
0.34 |
0.48 |
| Time difference: Lockdown to baseline |
0.14 |
-0.05 |
0.34 |
0.10 |
0.14 |
| 1750 |
0.03 |
0.03 |
9.60 |
2.04e-10 |
6 |
PCL baseline, not controlling for prior symptoms
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
8.44 |
8.35 |
8.54 |
0.05 |
0.00e+00 |
| Anxiety disorders |
3.42 |
3.16 |
3.67 |
0.13 |
3.65e-153 |
| Eating disorders |
3.66 |
2.85 |
4.46 |
0.41 |
6.61e-19 |
| OCDs |
5.54 |
4.88 |
6.20 |
0.34 |
1.20e-60 |
| PTSD |
6.20 |
5.54 |
6.86 |
0.34 |
1.99e-75 |
| Depressive disorders |
6.48 |
6.36 |
6.60 |
0.06 |
0.00e+00 |
| Bipolar disorders |
8.99 |
8.67 |
9.31 |
0.16 |
0.00e+00 |
| 31227 |
0.28 |
0.28 |
1988.78 |
0.00e+00 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
8.65 |
8.57 |
8.74 |
0.04 |
0.00e+00 |
| Depressive and anxiety disorder |
6.11 |
5.98 |
6.24 |
0.07 |
0.00e+00 |
| Only depressive disorder |
2.78 |
2.61 |
2.95 |
0.09 |
1.85e-216 |
| Only anxiety disorder |
3.28 |
3.06 |
3.50 |
0.11 |
6.19e-185 |
| Eating disorders |
1.34 |
1.11 |
1.57 |
0.12 |
5.16e-30 |
| OCDs |
1.74 |
1.52 |
1.97 |
0.11 |
1.82e-53 |
| Psychotic and bipolar disorder |
1.21 |
0.59 |
1.84 |
0.32 |
1.50e-04 |
| Only psychotic disorder |
0.72 |
0.19 |
1.26 |
0.27 |
0.008 |
| Only bipolar disorder |
1.16 |
0.82 |
1.50 |
0.17 |
1.61e-11 |
| PTSD |
2.86 |
2.65 |
3.06 |
0.10 |
7.16e-163 |
| ASD |
1.99 |
1.59 |
2.39 |
0.20 |
2.03e-22 |
| ADHD |
1.21 |
0.67 |
1.74 |
0.27 |
9.18e-06 |
| Personality disorder |
2.82 |
2.52 |
3.11 |
0.15 |
4.00e-78 |
| 31227 |
0.28 |
0.28 |
1988.78 |
0.00e+00 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
9.91 |
9.62 |
10.20 |
0.15 |
0.00e+00 |
| Anxiety disorders |
2.40 |
2.13 |
2.66 |
0.13 |
4.80e-72 |
| Eating disorders |
2.19 |
1.38 |
3.00 |
0.41 |
1.05e-07 |
| OCDs |
3.33 |
2.67 |
3.99 |
0.34 |
5.90e-23 |
| PTSD |
5.30 |
4.63 |
5.97 |
0.34 |
4.83e-54 |
| Depressive disorders |
5.42 |
5.28 |
5.55 |
0.07 |
0.00e+00 |
| Bipolar disorders |
7.78 |
7.47 |
8.10 |
0.16 |
0.00e+00 |
| Female |
0.77 |
0.63 |
0.91 |
0.07 |
8.71e-27 |
| Non-binary/Self-defined |
2.27 |
1.70 |
2.83 |
0.29 |
3.65e-15 |
| age_category_collapsed_reordered16-18 |
3.65 |
3.28 |
4.03 |
0.19 |
2.14e-80 |
| 19-25 years |
1.86 |
1.61 |
2.12 |
0.13 |
3.66e-45 |
| 36-45 years |
-0.77 |
-0.99 |
-0.55 |
0.11 |
3.10e-12 |
| 46-55 years |
-1.25 |
-1.45 |
-1.05 |
0.10 |
1.02e-34 |
| 56-65 years |
-2.18 |
-2.38 |
-1.99 |
0.10 |
1.23e-102 |
| 66-70 years |
-2.90 |
-3.15 |
-2.65 |
0.13 |
9.68e-112 |
| 71-75 years |
-3.05 |
-3.34 |
-2.76 |
0.15 |
1.57e-93 |
| 76+ years |
-2.87 |
-3.32 |
-2.43 |
0.23 |
3.77e-37 |
| Mixed or multiple ethnic origins |
0.56 |
0.11 |
1.01 |
0.23 |
0.02 |
| Asian or Asian British |
0.32 |
-0.23 |
0.87 |
0.28 |
0.25 |
| African or African British |
0.83 |
-0.09 |
1.76 |
0.47 |
0.08 |
| Other ethnicity |
0.99 |
0.16 |
1.82 |
0.42 |
0.02 |
| Time difference: Lockdown to baseline |
-0.01 |
-0.04 |
0.02 |
0.02 |
0.35 |
| 31227 |
0.28 |
0.28 |
1988.78 |
0.00e+00 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
9.95 |
9.67 |
10.23 |
0.14 |
0.00e+00 |
| Depressive and anxiety disorder |
5.23 |
5.08 |
5.37 |
0.07 |
0.00e+00 |
| Only depressive disorder |
2.64 |
2.46 |
2.82 |
0.09 |
1.59e-177 |
| Only anxiety disorder |
2.44 |
2.21 |
2.67 |
0.12 |
1.98e-95 |
| Eating disorders |
0.86 |
0.63 |
1.09 |
0.12 |
1.80e-13 |
| OCDs |
1.30 |
1.08 |
1.53 |
0.11 |
6.65e-31 |
| Psychotic and bipolar disorder |
1.44 |
0.82 |
2.06 |
0.32 |
5.13e-06 |
| Only psychotic disorder |
0.77 |
0.24 |
1.30 |
0.27 |
0.005 |
| Only bipolar disorder |
1.25 |
0.92 |
1.59 |
0.17 |
2.66e-13 |
| PTSD |
2.86 |
2.66 |
3.07 |
0.10 |
4.95e-163 |
| ASD |
1.07 |
0.67 |
1.47 |
0.21 |
1.77e-07 |
| ADHD |
0.60 |
0.07 |
1.14 |
0.27 |
0.03 |
| Personality disorder |
2.54 |
2.24 |
2.83 |
0.15 |
4.57e-64 |
| Female |
0.69 |
0.56 |
0.82 |
0.07 |
4.36e-24 |
| Non-binary/Self-defined |
1.20 |
0.67 |
1.73 |
0.27 |
1.05e-05 |
| age_category_collapsed_reordered16-18 |
3.78 |
3.43 |
4.13 |
0.18 |
5.85e-99 |
| 19-25 years |
1.73 |
1.49 |
1.98 |
0.12 |
1.15e-43 |
| 36-45 years |
-0.58 |
-0.79 |
-0.38 |
0.10 |
2.66e-08 |
| 46-55 years |
-0.86 |
-1.05 |
-0.67 |
0.10 |
9.23e-19 |
| 56-65 years |
-1.63 |
-1.82 |
-1.44 |
0.10 |
3.43e-62 |
| 66-70 years |
-2.37 |
-2.62 |
-2.12 |
0.13 |
9.67e-79 |
| 71-75 years |
-2.53 |
-2.81 |
-2.25 |
0.14 |
5.98e-69 |
| 76+ years |
-2.39 |
-2.81 |
-1.97 |
0.21 |
7.93e-29 |
| Mixed or multiple ethnic origins |
0.52 |
0.10 |
0.95 |
0.22 |
0.02 |
| Asian or Asian British |
0.77 |
0.26 |
1.28 |
0.26 |
0.003 |
| African or African British |
0.93 |
0.06 |
1.80 |
0.44 |
0.04 |
| Other ethnicity |
0.63 |
-0.15 |
1.41 |
0.40 |
0.11 |
| Key worker |
-0.54 |
-0.67 |
-0.42 |
0.06 |
5.68e-18 |
| Time difference: Lockdown to baseline |
-0.03 |
-0.05 |
0.00 |
0.01 |
0.07 |
| 31227 |
0.28 |
0.28 |
1988.78 |
0.00e+00 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
7.37 |
7.05 |
7.70 |
0.17 |
0.00e+00 |
| Anxiety disorders |
2.43 |
2.11 |
2.76 |
0.16 |
1.39e-49 |
| Eating disorders |
2.39 |
1.41 |
3.37 |
0.50 |
1.89e-06 |
| OCDs |
3.88 |
3.03 |
4.73 |
0.43 |
4.63e-19 |
| PTSD |
5.62 |
4.69 |
6.55 |
0.47 |
1.66e-32 |
| Depressive disorders |
5.83 |
5.67 |
5.99 |
0.08 |
0.00e+00 |
| Bipolar disorders |
8.10 |
7.74 |
8.47 |
0.18 |
0.00e+00 |
| Female |
0.54 |
0.38 |
0.69 |
0.08 |
3.21e-11 |
| Non-binary/Self-defined |
2.04 |
1.40 |
2.67 |
0.32 |
3.68e-10 |
| Age |
-229.09 |
-240.82 |
-217.36 |
5.98 |
2.96e-310 |
| Age^2 |
36.72 |
26.13 |
47.31 |
5.40 |
1.10e-11 |
| Mixed or multiple ethnic origins |
0.57 |
0.05 |
1.10 |
0.27 |
0.03 |
| Asian or Asian British |
0.67 |
-0.02 |
1.37 |
0.35 |
0.06 |
| African or African British |
1.16 |
0.07 |
2.25 |
0.56 |
0.04 |
| Other ethnicity |
1.29 |
0.30 |
2.28 |
0.51 |
0.01 |
| Time difference: Lockdown to baseline |
0.12 |
0.08 |
0.16 |
0.02 |
2.50e-09 |
| 24380 |
0.32 |
0.32 |
1898.00 |
0.00e+00 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
7.57 |
7.26 |
7.88 |
0.16 |
0.00e+00 |
| Depressive and anxiety disorder |
5.71 |
5.54 |
5.88 |
0.09 |
0.00e+00 |
| Only depressive disorder |
2.94 |
2.73 |
3.16 |
0.11 |
1.54e-155 |
| Only anxiety disorder |
2.67 |
2.39 |
2.96 |
0.14 |
2.70e-75 |
| Eating disorders |
1.09 |
0.82 |
1.35 |
0.13 |
6.52e-16 |
| OCDs |
1.31 |
1.06 |
1.56 |
0.13 |
3.87e-24 |
| Psychotic and bipolar disorder |
1.06 |
0.31 |
1.80 |
0.38 |
0.005 |
| Only psychotic disorder |
0.44 |
-0.17 |
1.04 |
0.31 |
0.16 |
| Only bipolar disorder |
1.23 |
0.86 |
1.60 |
0.19 |
6.52e-11 |
| PTSD |
2.88 |
2.65 |
3.12 |
0.12 |
1.27e-125 |
| ASD |
1.37 |
0.88 |
1.85 |
0.25 |
3.52e-08 |
| ADHD |
0.64 |
-0.02 |
1.29 |
0.33 |
0.06 |
| Personality disorder |
2.48 |
2.15 |
2.81 |
0.17 |
4.52e-48 |
| Female |
0.41 |
0.26 |
0.56 |
0.08 |
7.33e-08 |
| Non-binary/Self-defined |
0.96 |
0.36 |
1.57 |
0.31 |
0.002 |
| Age |
-191.84 |
-203.48 |
-180.21 |
5.94 |
6.38e-224 |
| Age^2 |
23.83 |
13.48 |
34.19 |
5.28 |
6.47e-06 |
| Mixed or multiple ethnic origins |
0.46 |
-0.04 |
0.95 |
0.25 |
0.07 |
| Asian or Asian British |
1.05 |
0.40 |
1.70 |
0.33 |
0.001 |
| African or African British |
1.17 |
0.14 |
2.19 |
0.52 |
0.03 |
| Other ethnicity |
0.76 |
-0.16 |
1.69 |
0.47 |
0.11 |
| Key worker |
-0.58 |
-0.72 |
-0.44 |
0.07 |
3.84e-16 |
| Time difference: Lockdown to baseline |
0.13 |
0.09 |
0.17 |
0.02 |
1.13e-11 |
| 24380 |
0.32 |
0.32 |
1898.00 |
0.00e+00 |
6 |
PCL prepan
Regression: Change scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
0.28 |
-0.70 |
1.26 |
0.50 |
0.58 |
| Anxiety disorders |
-0.07 |
-1.15 |
1.01 |
0.55 |
0.89 |
| Eating disorders |
-0.55 |
-2.63 |
1.53 |
1.06 |
0.61 |
| OCDs |
-0.30 |
-1.76 |
1.15 |
0.74 |
0.68 |
| PTSD |
-1.60 |
-3.30 |
0.10 |
0.86 |
0.06 |
| Depressive disorders |
-0.04 |
-1.03 |
0.94 |
0.50 |
0.93 |
| Bipolar disorders |
-0.27 |
-1.33 |
0.79 |
0.54 |
0.61 |
| 11019 |
0.00 |
0.00 |
1.05 |
0.39 |
6 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
0.39 |
-0.31 |
1.09 |
0.36 |
0.27 |
| Depressive and anxiety disorder |
0.02 |
-0.68 |
0.73 |
0.36 |
0.95 |
| Only depressive disorder |
-0.16 |
-0.92 |
0.61 |
0.39 |
0.69 |
| Only anxiety disorder |
-0.21 |
-1.01 |
0.59 |
0.41 |
0.61 |
| Eating disorders |
0.13 |
-0.21 |
0.48 |
0.18 |
0.45 |
| OCDs |
-0.08 |
-0.40 |
0.24 |
0.16 |
0.64 |
| Psychotic and bipolar disorder |
-0.69 |
-1.63 |
0.24 |
0.48 |
0.15 |
| Only psychotic disorder |
-0.03 |
-0.82 |
0.75 |
0.40 |
0.93 |
| Only bipolar disorder |
0.06 |
-0.41 |
0.53 |
0.24 |
0.79 |
| PTSD |
-0.89 |
-1.20 |
-0.59 |
0.15 |
7.68e-09 |
| ASD |
-0.12 |
-0.74 |
0.51 |
0.32 |
0.72 |
| ADHD |
-0.23 |
-1.09 |
0.63 |
0.44 |
0.60 |
| Personality disorder |
-0.29 |
-0.71 |
0.13 |
0.22 |
0.18 |
| 11019 |
0.00 |
0.00 |
1.05 |
0.39 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-0.50 |
-1.64 |
0.64 |
0.58 |
0.39 |
| Anxiety disorders |
-0.08 |
-1.16 |
1.00 |
0.55 |
0.88 |
| Eating disorders |
-0.67 |
-2.74 |
1.41 |
1.06 |
0.53 |
| OCDs |
-0.46 |
-1.92 |
0.99 |
0.74 |
0.53 |
| PTSD |
-1.60 |
-3.30 |
0.11 |
0.87 |
0.07 |
| Depressive disorders |
0.01 |
-0.97 |
1.00 |
0.50 |
0.98 |
| Bipolar disorders |
-0.12 |
-1.18 |
0.94 |
0.54 |
0.82 |
| Female |
0.62 |
0.33 |
0.91 |
0.15 |
2.26e-05 |
| Non-binary/Self-defined |
-0.04 |
-0.85 |
0.78 |
0.42 |
0.93 |
| age_category_collapsed_reordered16-18 |
-0.11 |
-0.80 |
0.57 |
0.35 |
0.74 |
| 19-25 years |
0.34 |
-0.03 |
0.71 |
0.19 |
0.07 |
| 36-45 years |
-0.47 |
-0.80 |
-0.14 |
0.17 |
0.005 |
| 46-55 years |
-0.57 |
-0.89 |
-0.25 |
0.16 |
4.38e-04 |
| 56-65 years |
-0.28 |
-0.64 |
0.07 |
0.18 |
0.12 |
| 66-70 years |
-0.47 |
-1.10 |
0.15 |
0.32 |
0.14 |
| 71-75 years |
-0.49 |
-1.32 |
0.35 |
0.43 |
0.26 |
| 76+ years |
0.33 |
-1.30 |
1.95 |
0.83 |
0.69 |
| Mixed or multiple ethnic origins |
0.37 |
-0.38 |
1.11 |
0.38 |
0.33 |
| Asian or Asian British |
0.12 |
-1.11 |
1.36 |
0.63 |
0.84 |
| African or African British |
-0.37 |
-2.18 |
1.44 |
0.92 |
0.69 |
| Other ethnicity |
-0.39 |
-1.55 |
0.77 |
0.59 |
0.51 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.06 |
| 11019 |
0.00 |
0.00 |
1.05 |
0.39 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-0.36 |
-1.29 |
0.56 |
0.47 |
0.44 |
| Depressive and anxiety disorder |
0.08 |
-0.63 |
0.79 |
0.36 |
0.82 |
| Only depressive disorder |
-0.03 |
-0.80 |
0.74 |
0.39 |
0.95 |
| Only anxiety disorder |
-0.23 |
-1.03 |
0.58 |
0.41 |
0.58 |
| Eating disorders |
0.00 |
-0.35 |
0.35 |
0.18 |
1.00 |
| OCDs |
-0.11 |
-0.43 |
0.21 |
0.16 |
0.50 |
| Psychotic and bipolar disorder |
-0.59 |
-1.53 |
0.34 |
0.48 |
0.22 |
| Only psychotic disorder |
0.07 |
-0.72 |
0.86 |
0.40 |
0.86 |
| Only bipolar disorder |
0.20 |
-0.28 |
0.67 |
0.24 |
0.41 |
| PTSD |
-0.87 |
-1.18 |
-0.57 |
0.16 |
1.96e-08 |
| ASD |
-0.12 |
-0.75 |
0.52 |
0.32 |
0.72 |
| ADHD |
-0.22 |
-1.08 |
0.64 |
0.44 |
0.62 |
| Personality disorder |
-0.43 |
-0.86 |
-0.01 |
0.22 |
0.05 |
| Female |
0.68 |
0.39 |
0.97 |
0.15 |
3.68e-06 |
| Non-binary/Self-defined |
0.17 |
-0.64 |
0.99 |
0.42 |
0.68 |
| age_category_collapsed_reordered16-18 |
-0.17 |
-0.85 |
0.51 |
0.35 |
0.63 |
| 19-25 years |
0.30 |
-0.08 |
0.67 |
0.19 |
0.12 |
| 36-45 years |
-0.45 |
-0.78 |
-0.13 |
0.17 |
0.007 |
| 46-55 years |
-0.55 |
-0.87 |
-0.23 |
0.16 |
8.32e-04 |
| 56-65 years |
-0.32 |
-0.69 |
0.04 |
0.18 |
0.08 |
| 66-70 years |
-0.62 |
-1.25 |
0.01 |
0.32 |
0.05 |
| 71-75 years |
-0.64 |
-1.48 |
0.20 |
0.43 |
0.13 |
| 76+ years |
0.11 |
-1.51 |
1.74 |
0.83 |
0.89 |
| Mixed or multiple ethnic origins |
0.45 |
-0.29 |
1.19 |
0.38 |
0.23 |
| Asian or Asian British |
0.23 |
-1.00 |
1.45 |
0.63 |
0.72 |
| African or African British |
-0.41 |
-2.22 |
1.40 |
0.92 |
0.66 |
| Other ethnicity |
-0.15 |
-1.29 |
0.99 |
0.58 |
0.80 |
| Key worker |
-0.21 |
-0.44 |
0.01 |
0.11 |
0.06 |
| Time difference: Lockdown to baseline |
0.07 |
0.00 |
0.13 |
0.03 |
0.04 |
| 11019 |
0.00 |
0.00 |
1.05 |
0.39 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-0.76 |
-1.88 |
0.36 |
0.57 |
0.18 |
| Anxiety disorders |
-0.07 |
-1.15 |
1.01 |
0.55 |
0.89 |
| Eating disorders |
-0.73 |
-2.80 |
1.35 |
1.06 |
0.49 |
| OCDs |
-0.49 |
-1.94 |
0.97 |
0.74 |
0.51 |
| PTSD |
-1.61 |
-3.31 |
0.09 |
0.87 |
0.06 |
| Depressive disorders |
0.02 |
-0.96 |
1.01 |
0.50 |
0.96 |
| Bipolar disorders |
-0.11 |
-1.17 |
0.95 |
0.54 |
0.84 |
| Female |
0.63 |
0.34 |
0.92 |
0.15 |
1.63e-05 |
| Non-binary/Self-defined |
-0.02 |
-0.84 |
0.80 |
0.42 |
0.96 |
| Age |
-23.23 |
-34.81 |
-11.64 |
5.91 |
8.52e-05 |
| Age^2 |
15.74 |
4.38 |
27.09 |
5.79 |
0.007 |
| Mixed or multiple ethnic origins |
0.36 |
-0.38 |
1.11 |
0.38 |
0.34 |
| Asian or Asian British |
0.11 |
-1.12 |
1.34 |
0.63 |
0.87 |
| African or African British |
-0.41 |
-2.22 |
1.41 |
0.92 |
0.66 |
| Other ethnicity |
-0.40 |
-1.56 |
0.76 |
0.59 |
0.50 |
| Time difference: Lockdown to baseline |
0.06 |
0.00 |
0.13 |
0.03 |
0.06 |
| 11019 |
0.00 |
0.00 |
1.05 |
0.39 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
-0.65 |
-1.54 |
0.24 |
0.45 |
0.15 |
| Depressive and anxiety disorder |
0.12 |
-0.60 |
0.83 |
0.36 |
0.75 |
| Only depressive disorder |
0.00 |
-0.76 |
0.77 |
0.39 |
0.99 |
| Only anxiety disorder |
-0.20 |
-1.01 |
0.60 |
0.41 |
0.62 |
| Eating disorders |
0.00 |
-0.35 |
0.34 |
0.18 |
0.98 |
| OCDs |
-0.11 |
-0.44 |
0.21 |
0.16 |
0.49 |
| Psychotic and bipolar disorder |
-0.58 |
-1.52 |
0.36 |
0.48 |
0.22 |
| Only psychotic disorder |
0.05 |
-0.73 |
0.84 |
0.40 |
0.90 |
| Only bipolar disorder |
0.19 |
-0.28 |
0.66 |
0.24 |
0.43 |
| PTSD |
-0.88 |
-1.18 |
-0.58 |
0.16 |
1.46e-08 |
| ASD |
-0.15 |
-0.78 |
0.48 |
0.32 |
0.64 |
| ADHD |
-0.23 |
-1.09 |
0.63 |
0.44 |
0.60 |
| Personality disorder |
-0.42 |
-0.84 |
0.01 |
0.22 |
0.05 |
| Female |
0.69 |
0.40 |
0.98 |
0.15 |
2.85e-06 |
| Non-binary/Self-defined |
0.19 |
-0.62 |
1.01 |
0.42 |
0.65 |
| Age |
-24.57 |
-36.35 |
-12.78 |
6.01 |
4.42e-05 |
| Age^2 |
10.83 |
-0.85 |
22.51 |
5.96 |
0.07 |
| Mixed or multiple ethnic origins |
0.45 |
-0.29 |
1.19 |
0.38 |
0.24 |
| Asian or Asian British |
0.21 |
-1.02 |
1.43 |
0.63 |
0.74 |
| African or African British |
-0.44 |
-2.25 |
1.37 |
0.92 |
0.63 |
| Other ethnicity |
-0.15 |
-1.29 |
0.99 |
0.58 |
0.79 |
| Key worker |
-0.21 |
-0.43 |
0.01 |
0.11 |
0.07 |
| Time difference: Lockdown to baseline |
0.07 |
0.00 |
0.13 |
0.03 |
0.05 |
| 11019 |
0.00 |
0.00 |
1.05 |
0.39 |
6 |
Regression: Absolute scores
Model 0a: Disorder_hierarchical, Unadjusted
| Intercept |
6.08 |
5.18 |
6.97 |
0.46 |
3.93e-40 |
| pcl.sum_score_prepan |
0.57 |
0.55 |
0.58 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.34 |
-1.30 |
0.62 |
0.49 |
0.49 |
| Eating disorders |
0.04 |
-1.81 |
1.89 |
0.94 |
0.97 |
| OCDs |
0.37 |
-0.92 |
1.66 |
0.66 |
0.57 |
| PTSD |
0.12 |
-1.39 |
1.62 |
0.77 |
0.88 |
| Depressive disorders |
0.94 |
0.06 |
1.82 |
0.45 |
0.04 |
| Bipolar disorders |
1.47 |
0.52 |
2.41 |
0.48 |
0.002 |
| 11019 |
0.33 |
0.33 |
764.66 |
0.00e+00 |
7 |
Model 0b: Overlapping disorders, Unadjusted
| Intercept |
6.83 |
6.17 |
7.48 |
0.33 |
7.35e-91 |
| pcl.sum_score_prepan |
0.53 |
0.52 |
0.55 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.51 |
-0.12 |
1.13 |
0.32 |
0.11 |
| Only depressive disorder |
-0.51 |
-1.19 |
0.16 |
0.34 |
0.14 |
| Only anxiety disorder |
-0.63 |
-1.34 |
0.08 |
0.36 |
0.08 |
| Eating disorders |
0.59 |
0.29 |
0.89 |
0.16 |
1.40e-04 |
| OCDs |
0.61 |
0.33 |
0.90 |
0.15 |
2.59e-05 |
| Psychotic and bipolar disorder |
-0.40 |
-1.23 |
0.42 |
0.42 |
0.34 |
| Only psychotic disorder |
-0.05 |
-0.74 |
0.65 |
0.35 |
0.89 |
| Only bipolar disorder |
0.35 |
-0.07 |
0.76 |
0.21 |
0.10 |
| PTSD |
0.73 |
0.46 |
1.01 |
0.14 |
1.43e-07 |
| ASD |
0.65 |
0.10 |
1.20 |
0.28 |
0.02 |
| ADHD |
0.24 |
-0.51 |
1.00 |
0.39 |
0.53 |
| Personality disorder |
1.08 |
0.71 |
1.46 |
0.19 |
1.71e-08 |
| 11081 |
0.02 |
0.02 |
32.92 |
1.45e-39 |
6 |
Model 1a: Disorder hierarchical, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.85 |
4.81 |
6.88 |
0.53 |
2.66e-28 |
| pcl.sum_score_prepan |
0.54 |
0.53 |
0.56 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.36 |
-1.31 |
0.59 |
0.49 |
0.46 |
| Eating disorders |
-0.01 |
-1.84 |
1.82 |
0.93 |
0.99 |
| OCDs |
0.11 |
-1.17 |
1.39 |
0.65 |
0.87 |
| PTSD |
0.49 |
-1.01 |
1.99 |
0.77 |
0.52 |
| Depressive disorders |
1.14 |
0.27 |
2.01 |
0.44 |
0.01 |
| Bipolar disorders |
1.77 |
0.83 |
2.71 |
0.48 |
2.22e-04 |
| Female |
0.58 |
0.32 |
0.83 |
0.13 |
8.54e-06 |
| Non-binary/Self-defined |
0.77 |
0.05 |
1.49 |
0.37 |
0.04 |
| age_category_collapsed_reordered16-18 |
1.00 |
0.39 |
1.62 |
0.31 |
0.001 |
| 19-25 years |
0.84 |
0.51 |
1.17 |
0.17 |
5.57e-07 |
| 36-45 years |
-0.51 |
-0.80 |
-0.22 |
0.15 |
4.87e-04 |
| 46-55 years |
-0.64 |
-0.92 |
-0.36 |
0.14 |
6.92e-06 |
| 56-65 years |
-0.92 |
-1.24 |
-0.60 |
0.16 |
1.31e-08 |
| 66-70 years |
-2.07 |
-2.63 |
-1.51 |
0.29 |
4.19e-13 |
| 71-75 years |
-2.46 |
-3.21 |
-1.72 |
0.38 |
8.96e-11 |
| 76+ years |
-1.94 |
-3.37 |
-0.51 |
0.73 |
0.008 |
| Mixed or multiple ethnic origins |
0.29 |
-0.37 |
0.95 |
0.34 |
0.39 |
| Asian or Asian British |
0.39 |
-0.70 |
1.48 |
0.55 |
0.48 |
| African or African British |
0.61 |
-0.98 |
2.21 |
0.81 |
0.45 |
| Other ethnicity |
0.14 |
-0.88 |
1.17 |
0.52 |
0.78 |
| Key worker |
-0.69 |
-0.88 |
-0.49 |
0.10 |
8.77e-12 |
| Time difference: Lockdown to baseline |
0.08 |
0.03 |
0.14 |
0.03 |
0.004 |
| 11081 |
0.02 |
0.02 |
32.92 |
1.45e-39 |
6 |
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.46 |
5.62 |
7.30 |
0.43 |
5.49e-51 |
| pcl.sum_score_prepan |
0.51 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.70 |
0.08 |
1.33 |
0.32 |
0.03 |
| Only depressive disorder |
-0.12 |
-0.79 |
0.55 |
0.34 |
0.73 |
| Only anxiety disorder |
-0.64 |
-1.35 |
0.06 |
0.36 |
0.07 |
| Eating disorders |
0.42 |
0.12 |
0.73 |
0.15 |
0.006 |
| OCDs |
0.52 |
0.23 |
0.80 |
0.14 |
3.41e-04 |
| Psychotic and bipolar disorder |
-0.20 |
-1.02 |
0.62 |
0.42 |
0.63 |
| Only psychotic disorder |
0.04 |
-0.65 |
0.72 |
0.35 |
0.92 |
| Only bipolar disorder |
0.51 |
0.10 |
0.92 |
0.21 |
0.02 |
| PTSD |
0.85 |
0.58 |
1.12 |
0.14 |
1.10e-09 |
| ASD |
0.37 |
-0.19 |
0.92 |
0.28 |
0.19 |
| ADHD |
0.16 |
-0.59 |
0.91 |
0.38 |
0.68 |
| Personality disorder |
0.93 |
0.55 |
1.30 |
0.19 |
1.31e-06 |
| Female |
0.46 |
0.21 |
0.72 |
0.13 |
3.36e-04 |
| Non-binary/Self-defined |
0.47 |
-0.25 |
1.18 |
0.36 |
0.20 |
| age_category_collapsed_reordered16-18 |
1.18 |
0.58 |
1.78 |
0.31 |
1.13e-04 |
| 19-25 years |
0.87 |
0.54 |
1.19 |
0.17 |
2.26e-07 |
| 36-45 years |
-0.48 |
-0.77 |
-0.19 |
0.15 |
0.001 |
| 46-55 years |
-0.57 |
-0.85 |
-0.29 |
0.14 |
6.38e-05 |
| 56-65 years |
-0.78 |
-1.10 |
-0.46 |
0.16 |
1.41e-06 |
| 66-70 years |
-1.83 |
-2.39 |
-1.28 |
0.28 |
9.37e-11 |
| 71-75 years |
-2.21 |
-2.95 |
-1.47 |
0.38 |
4.27e-09 |
| 76+ years |
-1.76 |
-3.19 |
-0.34 |
0.73 |
0.02 |
| Mixed or multiple ethnic origins |
0.24 |
-0.41 |
0.89 |
0.33 |
0.47 |
| Asian or Asian British |
0.52 |
-0.55 |
1.60 |
0.55 |
0.34 |
| African or African British |
0.75 |
-0.83 |
2.33 |
0.81 |
0.35 |
| Other ethnicity |
0.06 |
-0.94 |
1.06 |
0.51 |
0.91 |
| Key worker |
-0.59 |
-0.79 |
-0.40 |
0.10 |
2.77e-09 |
| Time difference: Lockdown to baseline |
0.09 |
0.04 |
0.15 |
0.03 |
0.002 |
| 11081 |
0.02 |
0.02 |
32.92 |
1.45e-39 |
6 |
Model 2a: Disorder hierarchical, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
5.49 |
4.47 |
6.50 |
0.52 |
4.74e-26 |
| pcl.sum_score_prepan |
0.54 |
0.53 |
0.56 |
0.01 |
0.00e+00 |
| Anxiety disorders |
-0.38 |
-1.33 |
0.58 |
0.49 |
0.44 |
| Eating disorders |
-0.11 |
-1.94 |
1.71 |
0.93 |
0.90 |
| OCDs |
0.11 |
-1.17 |
1.39 |
0.65 |
0.87 |
| PTSD |
0.40 |
-1.10 |
1.90 |
0.77 |
0.60 |
| Depressive disorders |
1.10 |
0.23 |
1.97 |
0.44 |
0.01 |
| Bipolar disorders |
1.72 |
0.78 |
2.66 |
0.48 |
3.28e-04 |
| Female |
0.57 |
0.32 |
0.82 |
0.13 |
1.09e-05 |
| Non-binary/Self-defined |
0.77 |
0.05 |
1.49 |
0.37 |
0.04 |
| Age |
-73.48 |
-83.85 |
-63.11 |
5.29 |
1.73e-43 |
| Age^2 |
2.03 |
-8.27 |
12.33 |
5.25 |
0.70 |
| Mixed or multiple ethnic origins |
0.27 |
-0.38 |
0.93 |
0.34 |
0.42 |
| Asian or Asian British |
0.38 |
-0.70 |
1.47 |
0.56 |
0.49 |
| African or African British |
0.61 |
-0.98 |
2.20 |
0.81 |
0.45 |
| Other ethnicity |
0.13 |
-0.89 |
1.16 |
0.52 |
0.80 |
| Key worker |
-0.69 |
-0.88 |
-0.49 |
0.10 |
9.55e-12 |
| Time difference: Lockdown to baseline |
0.09 |
0.03 |
0.14 |
0.03 |
0.004 |
| 11081 |
0.02 |
0.02 |
32.92 |
1.45e-39 |
6 |
Model 2b: Overlapping disorders, Adjusted with age^2
Model 0a + Gender_collapsed + age^2 + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.15 |
5.34 |
6.97 |
0.41 |
1.99e-49 |
| pcl.sum_score_prepan |
0.51 |
0.50 |
0.53 |
0.01 |
0.00e+00 |
| Depressive and anxiety disorder |
0.66 |
0.04 |
1.28 |
0.32 |
0.04 |
| Only depressive disorder |
-0.14 |
-0.81 |
0.54 |
0.34 |
0.69 |
| Only anxiety disorder |
-0.67 |
-1.37 |
0.04 |
0.36 |
0.06 |
| Eating disorders |
0.43 |
0.13 |
0.73 |
0.15 |
0.005 |
| OCDs |
0.51 |
0.23 |
0.79 |
0.14 |
3.97e-04 |
| Psychotic and bipolar disorder |
-0.18 |
-1.00 |
0.65 |
0.42 |
0.67 |
| Only psychotic disorder |
0.04 |
-0.65 |
0.72 |
0.35 |
0.92 |
| Only bipolar disorder |
0.50 |
0.08 |
0.91 |
0.21 |
0.02 |
| PTSD |
0.85 |
0.58 |
1.12 |
0.14 |
1.08e-09 |
| ASD |
0.39 |
-0.16 |
0.94 |
0.28 |
0.17 |
| ADHD |
0.10 |
-0.65 |
0.86 |
0.38 |
0.79 |
| Personality disorder |
0.88 |
0.51 |
1.26 |
0.19 |
3.70e-06 |
| Female |
0.46 |
0.20 |
0.71 |
0.13 |
4.05e-04 |
| Non-binary/Self-defined |
0.47 |
-0.24 |
1.19 |
0.36 |
0.19 |
| Age |
-68.40 |
-78.82 |
-57.98 |
5.32 |
1.31e-37 |
| Age^2 |
5.77 |
-4.45 |
16.00 |
5.22 |
0.27 |
| Mixed or multiple ethnic origins |
0.23 |
-0.42 |
0.88 |
0.33 |
0.49 |
| Asian or Asian British |
0.52 |
-0.56 |
1.59 |
0.55 |
0.35 |
| African or African British |
0.74 |
-0.84 |
2.32 |
0.81 |
0.36 |
| Other ethnicity |
0.04 |
-0.96 |
1.04 |
0.51 |
0.94 |
| Key worker |
-0.60 |
-0.79 |
-0.40 |
0.10 |
2.57e-09 |
| Time difference: Lockdown to baseline |
0.09 |
0.04 |
0.15 |
0.03 |
0.001 |
| 11081 |
0.02 |
0.02 |
32.92 |
1.45e-39 |
6 |
SENSITIVITY based on highest level of education
GAD prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
9.55 |
8.57 |
10.53 |
0.50 |
2.55e-80 |
| highest_education_numeric |
-0.67 |
-0.78 |
-0.56 |
0.06 |
1.55e-31 |
| Depressive and anxiety disorder |
1.39 |
0.70 |
2.08 |
0.35 |
7.95e-05 |
| Only depressive disorder |
-0.87 |
-1.62 |
-0.13 |
0.38 |
0.02 |
| Only anxiety disorder |
0.46 |
-0.32 |
1.24 |
0.40 |
0.24 |
| Eating disorders |
1.15 |
0.82 |
1.49 |
0.17 |
1.56e-11 |
| OCDs |
1.22 |
0.91 |
1.54 |
0.16 |
2.47e-14 |
| Psychotic and bipolar disorder |
0.00 |
-0.92 |
0.92 |
0.47 |
1.00 |
| Only psychotic disorder |
0.06 |
-0.71 |
0.82 |
0.39 |
0.88 |
| Only bipolar disorder |
0.33 |
-0.13 |
0.79 |
0.23 |
0.16 |
| PTSD |
1.37 |
1.07 |
1.66 |
0.15 |
1.31e-19 |
| ASD |
1.17 |
0.56 |
1.79 |
0.31 |
1.79e-04 |
| ADHD |
0.21 |
-0.62 |
1.04 |
0.42 |
0.62 |
| Personality disorder |
1.56 |
1.15 |
1.98 |
0.21 |
1.23e-13 |
| Female |
0.37 |
0.09 |
0.65 |
0.14 |
0.009 |
| Non-binary/Self-defined |
0.41 |
-0.38 |
1.19 |
0.40 |
0.31 |
| age_category_collapsed_reordered16-18 |
1.67 |
1.00 |
2.35 |
0.34 |
1.14e-06 |
| 19-25 years |
1.36 |
1.00 |
1.72 |
0.18 |
1.12e-13 |
| 36-45 years |
-0.55 |
-0.86 |
-0.23 |
0.16 |
6.85e-04 |
| 46-55 years |
-1.03 |
-1.34 |
-0.72 |
0.16 |
9.48e-11 |
| 56-65 years |
-2.13 |
-2.49 |
-1.78 |
0.18 |
3.16e-32 |
| 66-70 years |
-3.33 |
-3.95 |
-2.70 |
0.32 |
2.86e-25 |
| 71-75 years |
-3.89 |
-4.74 |
-3.05 |
0.43 |
1.93e-19 |
| 76+ years |
-3.68 |
-5.27 |
-2.09 |
0.81 |
5.54e-06 |
| Mixed or multiple ethnic origins |
-0.11 |
-0.82 |
0.61 |
0.36 |
0.77 |
| Asian or Asian British |
0.19 |
-0.97 |
1.36 |
0.60 |
0.74 |
| African or African British |
0.27 |
-1.53 |
2.07 |
0.92 |
0.77 |
| Other ethnicity |
1.04 |
-0.08 |
2.16 |
0.57 |
0.07 |
| Key worker |
-0.47 |
-0.69 |
-0.26 |
0.11 |
1.76e-05 |
| Time difference: Lockdown to baseline |
0.02 |
-0.05 |
0.08 |
0.03 |
0.63 |
| 11165 |
0.01 |
0.01 |
11.04 |
2.61e-12 |
6 |
PHQ prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
11.97 |
10.86 |
13.07 |
0.56 |
1.94e-98 |
| highest_education_numeric |
-0.87 |
-1.00 |
-0.75 |
0.06 |
7.62e-42 |
| Depressive and anxiety disorder |
1.71 |
0.93 |
2.49 |
0.40 |
1.65e-05 |
| Only depressive disorder |
0.93 |
0.09 |
1.77 |
0.43 |
0.03 |
| Only anxiety disorder |
-1.44 |
-2.32 |
-0.57 |
0.45 |
0.001 |
| Eating disorders |
1.83 |
1.45 |
2.21 |
0.19 |
2.46e-21 |
| OCDs |
1.18 |
0.83 |
1.53 |
0.18 |
6.49e-11 |
| Psychotic and bipolar disorder |
-0.17 |
-1.20 |
0.86 |
0.53 |
0.75 |
| Only psychotic disorder |
0.37 |
-0.49 |
1.24 |
0.44 |
0.40 |
| Only bipolar disorder |
0.97 |
0.45 |
1.49 |
0.26 |
2.26e-04 |
| PTSD |
1.65 |
1.32 |
1.98 |
0.17 |
3.60e-22 |
| ASD |
1.23 |
0.53 |
1.92 |
0.35 |
5.20e-04 |
| ADHD |
0.45 |
-0.49 |
1.38 |
0.48 |
0.35 |
| Personality disorder |
2.56 |
2.09 |
3.02 |
0.24 |
6.92e-27 |
| Female |
-0.07 |
-0.39 |
0.24 |
0.16 |
0.66 |
| Non-binary/Self-defined |
0.83 |
-0.05 |
1.72 |
0.45 |
0.07 |
| age_category_collapsed_reordered16-18 |
3.23 |
2.47 |
3.99 |
0.39 |
8.82e-17 |
| 19-25 years |
1.80 |
1.39 |
2.20 |
0.21 |
3.29e-18 |
| 36-45 years |
-0.50 |
-0.86 |
-0.15 |
0.18 |
0.006 |
| 46-55 years |
-0.72 |
-1.07 |
-0.37 |
0.18 |
5.49e-05 |
| 56-65 years |
-2.02 |
-2.42 |
-1.62 |
0.20 |
3.29e-23 |
| 66-70 years |
-4.04 |
-4.75 |
-3.33 |
0.36 |
4.66e-29 |
| 71-75 years |
-4.67 |
-5.62 |
-3.72 |
0.48 |
6.25e-22 |
| 76+ years |
-4.28 |
-6.08 |
-2.47 |
0.92 |
3.62e-06 |
| Mixed or multiple ethnic origins |
0.24 |
-0.56 |
1.04 |
0.41 |
0.56 |
| Asian or Asian British |
0.13 |
-1.19 |
1.44 |
0.67 |
0.85 |
| African or African British |
0.87 |
-1.16 |
2.90 |
1.04 |
0.40 |
| Other ethnicity |
0.56 |
-0.70 |
1.82 |
0.64 |
0.38 |
| Key worker |
-0.99 |
-1.23 |
-0.74 |
0.12 |
1.97e-15 |
| Time difference: Lockdown to baseline |
0.07 |
-0.01 |
0.14 |
0.04 |
0.07 |
| 11162 |
0.02 |
0.02 |
44.52 |
4.15e-54 |
6 |
OCIR prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
21.95 |
16.16 |
27.74 |
2.95 |
1.67e-13 |
| highest_education_numeric |
-1.50 |
-2.07 |
-0.93 |
0.29 |
2.53e-07 |
| Depressive and anxiety disorder |
-4.60 |
-9.14 |
-0.05 |
2.32 |
0.05 |
| Only depressive disorder |
-5.92 |
-10.86 |
-0.98 |
2.52 |
0.02 |
| Only anxiety disorder |
-7.55 |
-12.46 |
-2.63 |
2.51 |
0.003 |
| Eating disorders |
1.27 |
-0.32 |
2.86 |
0.81 |
0.12 |
| OCDs |
7.89 |
6.53 |
9.26 |
0.70 |
1.07e-28 |
| Psychotic and bipolar disorder |
6.53 |
2.24 |
10.83 |
2.19 |
0.003 |
| Only psychotic disorder |
1.40 |
-1.80 |
4.60 |
1.63 |
0.39 |
| Only bipolar disorder |
2.11 |
-0.17 |
4.40 |
1.17 |
0.07 |
| PTSD |
1.46 |
0.10 |
2.82 |
0.69 |
0.04 |
| ASD |
4.80 |
1.81 |
7.78 |
1.52 |
0.002 |
| ADHD |
0.35 |
-4.10 |
4.81 |
2.27 |
0.88 |
| Personality disorder |
2.93 |
1.14 |
4.72 |
0.91 |
0.001 |
| Female |
-0.92 |
-2.52 |
0.68 |
0.82 |
0.26 |
| Non-binary/Self-defined |
1.57 |
-2.23 |
5.37 |
1.94 |
0.42 |
| age_category_collapsed_reordered16-18 |
1.38 |
-2.60 |
5.35 |
2.03 |
0.50 |
| 19-25 years |
0.99 |
-0.85 |
2.83 |
0.94 |
0.29 |
| 36-45 years |
-0.60 |
-2.26 |
1.06 |
0.85 |
0.48 |
| 46-55 years |
0.57 |
-1.05 |
2.20 |
0.83 |
0.49 |
| 56-65 years |
-1.66 |
-3.52 |
0.21 |
0.95 |
0.08 |
| 66-70 years |
-0.67 |
-4.35 |
3.01 |
1.88 |
0.72 |
| 71-75 years |
-3.05 |
-8.21 |
2.10 |
2.63 |
0.25 |
| 76+ years |
-0.90 |
-12.16 |
10.35 |
5.74 |
0.88 |
| Mixed or multiple ethnic origins |
0.15 |
-3.31 |
3.60 |
1.76 |
0.93 |
| Asian or Asian British |
10.90 |
3.43 |
18.38 |
3.81 |
0.004 |
| African or African British |
8.63 |
-1.37 |
18.63 |
5.10 |
0.09 |
| Other ethnicity |
1.67 |
-3.03 |
6.37 |
2.40 |
0.49 |
| Key worker |
-0.98 |
-2.12 |
0.17 |
0.58 |
0.09 |
| Time difference: Lockdown to baseline |
0.35 |
0.01 |
0.69 |
0.17 |
0.04 |
| 1786 |
0.03 |
0.03 |
10.03 |
6.36e-11 |
6 |
#PCL prepan ## Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
16.04 |
15.00 |
17.07 |
0.53 |
1.02e-195 |
| highest_education_numeric |
-0.66 |
-0.77 |
-0.54 |
0.06 |
9.45e-28 |
| Depressive and anxiety disorder |
1.28 |
0.55 |
2.00 |
0.37 |
6.00e-04 |
| Only depressive disorder |
-0.25 |
-1.04 |
0.53 |
0.40 |
0.53 |
| Only anxiety disorder |
-1.04 |
-1.86 |
-0.22 |
0.42 |
0.01 |
| Eating disorders |
1.02 |
0.67 |
1.37 |
0.18 |
1.29e-08 |
| OCDs |
1.03 |
0.70 |
1.36 |
0.17 |
8.28e-10 |
| Psychotic and bipolar disorder |
0.22 |
-0.74 |
1.18 |
0.49 |
0.65 |
| Only psychotic disorder |
-0.06 |
-0.87 |
0.74 |
0.41 |
0.88 |
| Only bipolar disorder |
0.80 |
0.32 |
1.29 |
0.25 |
0.001 |
| PTSD |
2.52 |
2.21 |
2.83 |
0.16 |
2.10e-56 |
| ASD |
0.88 |
0.23 |
1.52 |
0.33 |
0.008 |
| ADHD |
0.48 |
-0.39 |
1.36 |
0.45 |
0.28 |
| Personality disorder |
2.24 |
1.81 |
2.68 |
0.22 |
7.18e-24 |
| Female |
0.19 |
-0.10 |
0.49 |
0.15 |
0.20 |
| Non-binary/Self-defined |
0.78 |
-0.05 |
1.61 |
0.42 |
0.06 |
| age_category_collapsed_reordered16-18 |
1.91 |
1.20 |
2.62 |
0.36 |
1.27e-07 |
| 19-25 years |
1.40 |
1.03 |
1.78 |
0.19 |
2.74e-13 |
| 36-45 years |
-0.60 |
-0.94 |
-0.27 |
0.17 |
3.68e-04 |
| 46-55 years |
-0.81 |
-1.14 |
-0.49 |
0.17 |
1.12e-06 |
| 56-65 years |
-1.59 |
-1.96 |
-1.22 |
0.19 |
5.61e-17 |
| 66-70 years |
-3.15 |
-3.82 |
-2.49 |
0.34 |
1.30e-20 |
| 71-75 years |
-4.05 |
-4.94 |
-3.16 |
0.45 |
5.78e-19 |
| 76+ years |
-3.94 |
-5.60 |
-2.27 |
0.85 |
3.53e-06 |
| Mixed or multiple ethnic origins |
0.14 |
-0.61 |
0.89 |
0.38 |
0.72 |
| Asian or Asian British |
0.73 |
-0.51 |
1.96 |
0.63 |
0.25 |
| African or African British |
2.04 |
0.15 |
3.92 |
0.96 |
0.03 |
| Other ethnicity |
0.15 |
-1.03 |
1.33 |
0.60 |
0.80 |
| Key worker |
-0.84 |
-1.07 |
-0.61 |
0.12 |
3.87e-13 |
| Time difference: Lockdown to baseline |
0.12 |
0.05 |
0.18 |
0.03 |
7.92e-04 |
| 11081 |
0.02 |
0.02 |
32.92 |
1.45e-39 |
6 |
SENSITIVITY based on employment status
GAD prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
6.99 |
6.10 |
7.87 |
0.45 |
8.76e-54 |
| employment.unemployed_numeric |
1.56 |
1.19 |
1.94 |
0.19 |
4.85e-16 |
| Depressive and anxiety disorder |
1.38 |
0.70 |
2.06 |
0.35 |
7.25e-05 |
| Only depressive disorder |
-0.91 |
-1.64 |
-0.17 |
0.37 |
0.02 |
| Only anxiety disorder |
0.43 |
-0.34 |
1.20 |
0.39 |
0.27 |
| Eating disorders |
1.07 |
0.74 |
1.40 |
0.17 |
2.56e-10 |
| OCDs |
1.25 |
0.94 |
1.56 |
0.16 |
3.01e-15 |
| Psychotic and bipolar disorder |
-0.25 |
-1.15 |
0.66 |
0.46 |
0.60 |
| Only psychotic disorder |
0.05 |
-0.70 |
0.81 |
0.38 |
0.89 |
| Only bipolar disorder |
0.31 |
-0.14 |
0.76 |
0.23 |
0.17 |
| PTSD |
1.45 |
1.16 |
1.74 |
0.15 |
1.86e-22 |
| ASD |
1.03 |
0.43 |
1.64 |
0.31 |
8.53e-04 |
| ADHD |
0.26 |
-0.55 |
1.08 |
0.42 |
0.53 |
| Personality disorder |
1.61 |
1.21 |
2.02 |
0.21 |
8.10e-15 |
| Female |
0.40 |
0.13 |
0.68 |
0.14 |
0.004 |
| Non-binary/Self-defined |
0.35 |
-0.44 |
1.13 |
0.40 |
0.39 |
| age_category_collapsed_reordered16-18 |
2.52 |
1.87 |
3.18 |
0.33 |
4.27e-14 |
| 19-25 years |
1.42 |
1.07 |
1.78 |
0.18 |
7.17e-15 |
| 36-45 years |
-0.42 |
-0.73 |
-0.10 |
0.16 |
0.009 |
| 46-55 years |
-0.79 |
-1.09 |
-0.48 |
0.16 |
4.91e-07 |
| 56-65 years |
-1.75 |
-2.10 |
-1.41 |
0.18 |
3.21e-23 |
| 66-70 years |
-3.03 |
-3.64 |
-2.43 |
0.31 |
1.19e-22 |
| 71-75 years |
-3.49 |
-4.29 |
-2.69 |
0.41 |
1.58e-17 |
| 76+ years |
-3.17 |
-4.72 |
-1.62 |
0.79 |
6.05e-05 |
| Mixed or multiple ethnic origins |
-0.19 |
-0.90 |
0.52 |
0.36 |
0.60 |
| Asian or Asian British |
0.12 |
-1.03 |
1.28 |
0.59 |
0.84 |
| African or African British |
0.34 |
-1.40 |
2.08 |
0.89 |
0.70 |
| Other ethnicity |
0.81 |
-0.28 |
1.91 |
0.56 |
0.14 |
| Key worker |
-0.37 |
-0.59 |
-0.15 |
0.11 |
0.001 |
| Time difference: Lockdown to baseline |
0.01 |
-0.05 |
0.08 |
0.03 |
0.67 |
| 11165 |
0.01 |
0.01 |
11.04 |
2.61e-12 |
6 |
PHQ prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
8.56 |
7.57 |
9.55 |
0.51 |
2.72e-63 |
| employment.unemployed_numeric |
2.76 |
2.34 |
3.19 |
0.22 |
4.96e-37 |
| Depressive and anxiety disorder |
1.59 |
0.82 |
2.35 |
0.39 |
4.67e-05 |
| Only depressive disorder |
0.72 |
-0.10 |
1.55 |
0.42 |
0.09 |
| Only anxiety disorder |
-1.53 |
-2.39 |
-0.67 |
0.44 |
5.22e-04 |
| Eating disorders |
1.71 |
1.33 |
2.08 |
0.19 |
3.22e-19 |
| OCDs |
1.25 |
0.90 |
1.59 |
0.18 |
2.53e-12 |
| Psychotic and bipolar disorder |
-0.50 |
-1.52 |
0.52 |
0.52 |
0.34 |
| Only psychotic disorder |
0.22 |
-0.63 |
1.06 |
0.43 |
0.62 |
| Only bipolar disorder |
0.94 |
0.43 |
1.44 |
0.26 |
2.86e-04 |
| PTSD |
1.67 |
1.34 |
1.99 |
0.17 |
2.57e-23 |
| ASD |
0.93 |
0.24 |
1.61 |
0.35 |
0.008 |
| ADHD |
0.65 |
-0.27 |
1.57 |
0.47 |
0.17 |
| Personality disorder |
2.58 |
2.12 |
3.04 |
0.23 |
3.16e-28 |
| Female |
0.02 |
-0.30 |
0.33 |
0.16 |
0.92 |
| Non-binary/Self-defined |
0.76 |
-0.12 |
1.64 |
0.45 |
0.09 |
| age_category_collapsed_reordered16-18 |
4.29 |
3.56 |
5.03 |
0.38 |
4.34e-30 |
| 19-25 years |
1.85 |
1.45 |
2.26 |
0.21 |
2.63e-19 |
| 36-45 years |
-0.40 |
-0.75 |
-0.04 |
0.18 |
0.03 |
| 46-55 years |
-0.44 |
-0.78 |
-0.09 |
0.18 |
0.01 |
| 56-65 years |
-1.55 |
-1.94 |
-1.16 |
0.20 |
6.51e-15 |
| 66-70 years |
-3.50 |
-4.18 |
-2.82 |
0.35 |
8.99e-24 |
| 71-75 years |
-4.19 |
-5.09 |
-3.29 |
0.46 |
8.97e-20 |
| 76+ years |
-3.85 |
-5.61 |
-2.09 |
0.90 |
1.83e-05 |
| Mixed or multiple ethnic origins |
0.16 |
-0.64 |
0.96 |
0.41 |
0.69 |
| Asian or Asian British |
-0.01 |
-1.31 |
1.29 |
0.66 |
0.99 |
| African or African British |
0.63 |
-1.33 |
2.59 |
1.00 |
0.53 |
| Other ethnicity |
0.58 |
-0.65 |
1.81 |
0.63 |
0.35 |
| Key worker |
-0.76 |
-1.01 |
-0.51 |
0.13 |
2.21e-09 |
| Time difference: Lockdown to baseline |
0.07 |
0.00 |
0.14 |
0.04 |
0.06 |
| 11162 |
0.02 |
0.02 |
44.52 |
4.15e-54 |
6 |
OCIR prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
15.16 |
9.69 |
20.62 |
2.79 |
6.22e-08 |
| employment.unemployed_numeric |
3.07 |
1.31 |
4.82 |
0.90 |
6.27e-04 |
| Depressive and anxiety disorder |
-4.38 |
-8.98 |
0.22 |
2.35 |
0.06 |
| Only depressive disorder |
-6.24 |
-11.23 |
-1.25 |
2.55 |
0.01 |
| Only anxiety disorder |
-7.52 |
-12.50 |
-2.53 |
2.54 |
0.003 |
| Eating disorders |
0.98 |
-0.60 |
2.56 |
0.81 |
0.22 |
| OCDs |
7.54 |
6.18 |
8.90 |
0.69 |
1.01e-26 |
| Psychotic and bipolar disorder |
4.73 |
0.65 |
8.81 |
2.08 |
0.02 |
| Only psychotic disorder |
1.44 |
-1.75 |
4.63 |
1.63 |
0.38 |
| Only bipolar disorder |
2.89 |
0.64 |
5.15 |
1.15 |
0.01 |
| PTSD |
1.95 |
0.61 |
3.30 |
0.69 |
0.004 |
| ASD |
4.91 |
1.97 |
7.84 |
1.50 |
0.001 |
| ADHD |
-0.27 |
-4.55 |
4.01 |
2.18 |
0.90 |
| Personality disorder |
3.24 |
1.47 |
5.02 |
0.91 |
3.52e-04 |
| Female |
-0.63 |
-2.22 |
0.97 |
0.81 |
0.44 |
| Non-binary/Self-defined |
1.10 |
-2.73 |
4.93 |
1.95 |
0.57 |
| age_category_collapsed_reordered16-18 |
3.66 |
-0.28 |
7.59 |
2.01 |
0.07 |
| 19-25 years |
0.97 |
-0.88 |
2.83 |
0.95 |
0.30 |
| 36-45 years |
-0.39 |
-2.04 |
1.27 |
0.84 |
0.65 |
| 46-55 years |
0.99 |
-0.62 |
2.60 |
0.82 |
0.23 |
| 56-65 years |
-0.43 |
-2.27 |
1.41 |
0.94 |
0.65 |
| 66-70 years |
-0.71 |
-4.33 |
2.91 |
1.85 |
0.70 |
| 71-75 years |
-2.94 |
-8.05 |
2.16 |
2.60 |
0.26 |
| 76+ years |
-0.67 |
-12.07 |
10.74 |
5.82 |
0.91 |
| Mixed or multiple ethnic origins |
0.18 |
-3.32 |
3.69 |
1.79 |
0.92 |
| Asian or Asian British |
10.34 |
2.76 |
17.92 |
3.86 |
0.008 |
| African or African British |
8.39 |
-1.74 |
18.52 |
5.16 |
0.10 |
| Other ethnicity |
2.00 |
-2.76 |
6.76 |
2.43 |
0.41 |
| Key worker |
-0.91 |
-2.09 |
0.28 |
0.60 |
0.13 |
| Time difference: Lockdown to baseline |
0.47 |
0.14 |
0.80 |
0.17 |
0.005 |
| 1786 |
0.03 |
0.03 |
10.03 |
6.36e-11 |
6 |
#PCL prepan ## Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
13.38 |
12.45 |
14.31 |
0.47 |
4.65e-169 |
| employment.unemployed_numeric |
2.00 |
1.61 |
2.40 |
0.20 |
4.57e-23 |
| Depressive and anxiety disorder |
1.29 |
0.57 |
2.01 |
0.37 |
4.26e-04 |
| Only depressive disorder |
-0.26 |
-1.04 |
0.51 |
0.39 |
0.51 |
| Only anxiety disorder |
-1.02 |
-1.83 |
-0.21 |
0.41 |
0.01 |
| Eating disorders |
0.89 |
0.54 |
1.23 |
0.18 |
6.05e-07 |
| OCDs |
1.10 |
0.77 |
1.42 |
0.17 |
3.51e-11 |
| Psychotic and bipolar disorder |
0.04 |
-0.91 |
0.98 |
0.48 |
0.94 |
| Only psychotic disorder |
-0.07 |
-0.86 |
0.72 |
0.40 |
0.85 |
| Only bipolar disorder |
0.76 |
0.28 |
1.23 |
0.24 |
0.002 |
| PTSD |
2.58 |
2.27 |
2.88 |
0.16 |
1.38e-60 |
| ASD |
0.80 |
0.17 |
1.44 |
0.32 |
0.01 |
| ADHD |
0.55 |
-0.32 |
1.41 |
0.44 |
0.21 |
| Personality disorder |
2.23 |
1.80 |
2.66 |
0.22 |
2.07e-24 |
| Female |
0.27 |
-0.02 |
0.56 |
0.15 |
0.07 |
| Non-binary/Self-defined |
0.70 |
-0.12 |
1.52 |
0.42 |
0.09 |
| age_category_collapsed_reordered16-18 |
2.65 |
1.96 |
3.33 |
0.35 |
4.56e-14 |
| 19-25 years |
1.44 |
1.06 |
1.81 |
0.19 |
7.15e-14 |
| 36-45 years |
-0.51 |
-0.84 |
-0.18 |
0.17 |
0.003 |
| 46-55 years |
-0.62 |
-0.95 |
-0.30 |
0.16 |
1.42e-04 |
| 56-65 years |
-1.21 |
-1.57 |
-0.85 |
0.19 |
7.05e-11 |
| 66-70 years |
-2.84 |
-3.48 |
-2.20 |
0.33 |
3.52e-18 |
| 71-75 years |
-3.53 |
-4.37 |
-2.68 |
0.43 |
2.81e-16 |
| 76+ years |
-3.35 |
-4.97 |
-1.73 |
0.83 |
5.26e-05 |
| Mixed or multiple ethnic origins |
0.00 |
-0.75 |
0.74 |
0.38 |
0.99 |
| Asian or Asian British |
0.86 |
-0.36 |
2.08 |
0.62 |
0.17 |
| African or African British |
1.91 |
0.09 |
3.73 |
0.93 |
0.04 |
| Other ethnicity |
0.23 |
-0.92 |
1.38 |
0.59 |
0.69 |
| Key worker |
-0.69 |
-0.93 |
-0.46 |
0.12 |
5.30e-09 |
| Time difference: Lockdown to baseline |
0.12 |
0.05 |
0.18 |
0.03 |
4.73e-04 |
| 11081 |
0.02 |
0.02 |
32.92 |
1.45e-39 |
6 |
SENSITIVITY based on employment change
GAD prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
8.20 |
7.08 |
9.32 |
0.57 |
3.58e-46 |
| employment_changeFurlough |
-1.15 |
-1.76 |
-0.53 |
0.31 |
2.76e-04 |
| employment_changeKey Worker |
-1.63 |
-2.29 |
-0.96 |
0.34 |
1.88e-06 |
| employment_changeRetired |
-1.14 |
-1.86 |
-0.42 |
0.37 |
0.002 |
| employment_changeStudent |
-0.72 |
-1.43 |
-0.01 |
0.36 |
0.05 |
| employment_changeUnemployed |
0.72 |
0.06 |
1.38 |
0.34 |
0.03 |
| employment_changeZero Hours Contract |
-1.40 |
-3.20 |
0.39 |
0.92 |
0.13 |
| Depressive and anxiety disorder |
1.16 |
0.42 |
1.89 |
0.38 |
0.002 |
| Only depressive disorder |
-1.07 |
-1.87 |
-0.27 |
0.41 |
0.008 |
| Only anxiety disorder |
0.34 |
-0.50 |
1.18 |
0.43 |
0.43 |
| Eating disorders |
1.30 |
0.92 |
1.67 |
0.19 |
1.39e-11 |
| OCDs |
1.05 |
0.69 |
1.40 |
0.18 |
5.61e-09 |
| Psychotic and bipolar disorder |
-0.30 |
-1.33 |
0.73 |
0.53 |
0.57 |
| Only psychotic disorder |
-0.06 |
-0.90 |
0.78 |
0.43 |
0.89 |
| Only bipolar disorder |
0.26 |
-0.27 |
0.78 |
0.27 |
0.34 |
| PTSD |
1.34 |
1.01 |
1.67 |
0.17 |
1.56e-15 |
| ASD |
1.01 |
0.32 |
1.70 |
0.35 |
0.004 |
| ADHD |
0.30 |
-0.63 |
1.24 |
0.48 |
0.52 |
| Personality disorder |
1.42 |
0.95 |
1.90 |
0.24 |
4.68e-09 |
| Female |
0.34 |
0.03 |
0.65 |
0.16 |
0.03 |
| Non-binary/Self-defined |
0.19 |
-0.70 |
1.07 |
0.45 |
0.68 |
| age_category_collapsed_reordered16-18 |
2.33 |
1.63 |
3.03 |
0.36 |
7.30e-11 |
| 19-25 years |
1.37 |
0.96 |
1.77 |
0.21 |
4.30e-11 |
| 36-45 years |
-0.45 |
-0.81 |
-0.08 |
0.19 |
0.02 |
| 46-55 years |
-0.99 |
-1.34 |
-0.63 |
0.18 |
5.12e-08 |
| 56-65 years |
-1.88 |
-2.32 |
-1.44 |
0.22 |
3.00e-17 |
| 66-70 years |
-2.94 |
-3.69 |
-2.19 |
0.38 |
1.64e-14 |
| 71-75 years |
-3.42 |
-4.35 |
-2.50 |
0.47 |
3.85e-13 |
| 76+ years |
-3.20 |
-4.82 |
-1.59 |
0.82 |
1.03e-04 |
| Mixed or multiple ethnic origins |
0.01 |
-0.79 |
0.81 |
0.41 |
0.98 |
| Asian or Asian British |
-0.33 |
-1.61 |
0.94 |
0.65 |
0.61 |
| African or African British |
0.12 |
-1.90 |
2.14 |
1.03 |
0.91 |
| Other ethnicity |
0.73 |
-0.49 |
1.95 |
0.62 |
0.24 |
| Key worker |
0.26 |
-0.28 |
0.80 |
0.27 |
0.34 |
| Time difference: Lockdown to baseline |
0.02 |
-0.05 |
0.09 |
0.04 |
0.57 |
| 11165 |
0.01 |
0.01 |
11.04 |
2.61e-12 |
6 |
PHQ prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
9.89 |
8.63 |
11.15 |
0.64 |
7.83e-53 |
| employment_changeFurlough |
-1.42 |
-2.11 |
-0.72 |
0.35 |
6.27e-05 |
| employment_changeKey Worker |
-2.09 |
-2.84 |
-1.34 |
0.38 |
5.11e-08 |
| employment_changeRetired |
-1.12 |
-1.93 |
-0.31 |
0.41 |
0.007 |
| employment_changeStudent |
-0.67 |
-1.47 |
0.13 |
0.41 |
0.10 |
| employment_changeUnemployed |
1.84 |
1.10 |
2.58 |
0.38 |
1.07e-06 |
| employment_changeZero Hours Contract |
-1.36 |
-3.38 |
0.66 |
1.03 |
0.19 |
| Depressive and anxiety disorder |
1.45 |
0.62 |
2.28 |
0.42 |
5.91e-04 |
| Only depressive disorder |
0.64 |
-0.25 |
1.54 |
0.46 |
0.16 |
| Only anxiety disorder |
-1.50 |
-2.44 |
-0.56 |
0.48 |
0.002 |
| Eating disorders |
1.77 |
1.35 |
2.20 |
0.22 |
1.87e-16 |
| OCDs |
1.07 |
0.68 |
1.47 |
0.20 |
9.69e-08 |
| Psychotic and bipolar disorder |
-0.79 |
-1.96 |
0.38 |
0.60 |
0.18 |
| Only psychotic disorder |
0.27 |
-0.67 |
1.22 |
0.48 |
0.57 |
| Only bipolar disorder |
1.01 |
0.42 |
1.59 |
0.30 |
8.29e-04 |
| PTSD |
1.36 |
0.99 |
1.73 |
0.19 |
5.28e-13 |
| ASD |
0.93 |
0.16 |
1.71 |
0.40 |
0.02 |
| ADHD |
0.71 |
-0.34 |
1.76 |
0.54 |
0.19 |
| Personality disorder |
2.17 |
1.64 |
2.71 |
0.27 |
1.87e-15 |
| Female |
0.03 |
-0.32 |
0.38 |
0.18 |
0.87 |
| Non-binary/Self-defined |
0.53 |
-0.47 |
1.52 |
0.51 |
0.30 |
| age_category_collapsed_reordered16-18 |
3.96 |
3.17 |
4.74 |
0.40 |
6.95e-23 |
| 19-25 years |
1.73 |
1.27 |
2.18 |
0.23 |
1.18e-13 |
| 36-45 years |
-0.52 |
-0.93 |
-0.10 |
0.21 |
0.01 |
| 46-55 years |
-0.80 |
-1.20 |
-0.40 |
0.20 |
8.52e-05 |
| 56-65 years |
-1.92 |
-2.41 |
-1.43 |
0.25 |
1.55e-14 |
| 66-70 years |
-3.67 |
-4.51 |
-2.82 |
0.43 |
1.69e-17 |
| 71-75 years |
-4.36 |
-5.40 |
-3.33 |
0.53 |
1.62e-16 |
| 76+ years |
-4.12 |
-5.95 |
-2.29 |
0.93 |
1.05e-05 |
| Mixed or multiple ethnic origins |
0.28 |
-0.62 |
1.19 |
0.46 |
0.54 |
| Asian or Asian British |
-0.41 |
-1.84 |
1.02 |
0.73 |
0.58 |
| African or African British |
0.64 |
-1.63 |
2.90 |
1.15 |
0.58 |
| Other ethnicity |
0.70 |
-0.67 |
2.07 |
0.70 |
0.32 |
| Key worker |
0.16 |
-0.44 |
0.77 |
0.31 |
0.59 |
| Time difference: Lockdown to baseline |
0.08 |
0.00 |
0.16 |
0.04 |
0.05 |
| 11162 |
0.02 |
0.02 |
44.52 |
4.15e-54 |
6 |
OCIR prepan
Regression: Absolute scores
Model 1b: Overlapping disorders, Adjusted
Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
13.46 |
6.70 |
20.23 |
3.45 |
9.84e-05 |
| employment_changeFurlough |
0.05 |
-2.99 |
3.10 |
1.55 |
0.97 |
| employment_changeKey Worker |
0.64 |
-2.65 |
3.92 |
1.68 |
0.70 |
| employment_changeRetired |
2.94 |
-0.62 |
6.49 |
1.81 |
0.11 |
| employment_changeStudent |
1.50 |
-2.11 |
5.11 |
1.84 |
0.42 |
| employment_changeUnemployed |
4.79 |
1.61 |
7.98 |
1.62 |
0.003 |
| employment_changeZero Hours Contract |
-6.29 |
-22.47 |
9.90 |
8.25 |
0.45 |
| Depressive and anxiety disorder |
-3.58 |
-8.75 |
1.59 |
2.64 |
0.17 |
| Only depressive disorder |
-5.29 |
-10.87 |
0.29 |
2.84 |
0.06 |
| Only anxiety disorder |
-6.28 |
-11.84 |
-0.71 |
2.84 |
0.03 |
| Eating disorders |
2.06 |
0.23 |
3.89 |
0.93 |
0.03 |
| OCDs |
6.66 |
5.11 |
8.22 |
0.79 |
1.20e-16 |
| Psychotic and bipolar disorder |
3.62 |
-0.95 |
8.19 |
2.33 |
0.12 |
| Only psychotic disorder |
0.82 |
-2.78 |
4.41 |
1.83 |
0.66 |
| Only bipolar disorder |
3.76 |
1.15 |
6.36 |
1.33 |
0.005 |
| PTSD |
1.77 |
0.21 |
3.32 |
0.79 |
0.03 |
| ASD |
5.99 |
2.55 |
9.42 |
1.75 |
6.49e-04 |
| ADHD |
-0.60 |
-5.59 |
4.40 |
2.55 |
0.81 |
| Personality disorder |
3.92 |
1.78 |
6.05 |
1.09 |
3.35e-04 |
| Female |
-0.83 |
-2.63 |
0.97 |
0.92 |
0.37 |
| Non-binary/Self-defined |
1.30 |
-3.20 |
5.80 |
2.29 |
0.57 |
| age_category_collapsed_reordered16-18 |
3.80 |
-0.34 |
7.93 |
2.11 |
0.07 |
| 19-25 years |
0.91 |
-1.19 |
3.01 |
1.07 |
0.39 |
| 36-45 years |
-0.70 |
-2.63 |
1.24 |
0.99 |
0.48 |
| 46-55 years |
0.93 |
-0.99 |
2.84 |
0.98 |
0.34 |
| 56-65 years |
-0.90 |
-3.22 |
1.42 |
1.18 |
0.45 |
| 66-70 years |
-1.68 |
-6.02 |
2.65 |
2.21 |
0.45 |
| 71-75 years |
-3.98 |
-9.48 |
1.53 |
2.80 |
0.16 |
| 76+ years |
-1.12 |
-12.71 |
10.47 |
5.91 |
0.85 |
| Mixed or multiple ethnic origins |
1.20 |
-2.71 |
5.10 |
1.99 |
0.55 |
| Asian or Asian British |
8.25 |
0.18 |
16.32 |
4.11 |
0.05 |
| African or African British |
21.05 |
5.01 |
37.08 |
8.18 |
0.01 |
| Other ethnicity |
2.66 |
-3.24 |
8.57 |
3.01 |
0.38 |
| Key worker |
0.40 |
-2.41 |
3.20 |
1.43 |
0.78 |
| Time difference: Lockdown to baseline |
0.37 |
-0.02 |
0.75 |
0.20 |
0.06 |
| 1786 |
0.03 |
0.03 |
10.03 |
6.36e-11 |
6 |
#PCL prepan ## Regression: Absolute scores ### Model 1b: Overlapping disorders, Adjusted Model 0a + Gender_collapsed + age_category_collapsed + Ethnicity_collapsed + Time registration and baseline
| Intercept |
14.81 |
13.63 |
15.99 |
0.60 |
2.54e-129 |
| employment_changeFurlough |
-1.70 |
-2.35 |
-1.05 |
0.33 |
2.75e-07 |
| employment_changeKey Worker |
-2.42 |
-3.12 |
-1.72 |
0.36 |
1.41e-11 |
| employment_changeRetired |
-1.76 |
-2.51 |
-1.00 |
0.39 |
5.32e-06 |
| employment_changeStudent |
-1.13 |
-1.88 |
-0.38 |
0.38 |
0.003 |
| employment_changeUnemployed |
0.64 |
-0.05 |
1.33 |
0.35 |
0.07 |
| employment_changeZero Hours Contract |
-0.99 |
-2.89 |
0.92 |
0.97 |
0.31 |
| Depressive and anxiety disorder |
1.36 |
0.58 |
2.14 |
0.40 |
6.18e-04 |
| Only depressive disorder |
-0.13 |
-0.97 |
0.71 |
0.43 |
0.76 |
| Only anxiety disorder |
-0.88 |
-1.77 |
0.00 |
0.45 |
0.05 |
| Eating disorders |
1.03 |
0.64 |
1.43 |
0.20 |
2.73e-07 |
| OCDs |
0.92 |
0.55 |
1.29 |
0.19 |
1.02e-06 |
| Psychotic and bipolar disorder |
0.00 |
-1.09 |
1.08 |
0.55 |
1.00 |
| Only psychotic disorder |
-0.01 |
-0.89 |
0.87 |
0.45 |
0.98 |
| Only bipolar disorder |
0.72 |
0.16 |
1.27 |
0.28 |
0.01 |
| PTSD |
2.40 |
2.05 |
2.74 |
0.18 |
1.82e-41 |
| ASD |
0.86 |
0.13 |
1.58 |
0.37 |
0.02 |
| ADHD |
0.61 |
-0.38 |
1.59 |
0.50 |
0.23 |
| Personality disorder |
1.95 |
1.45 |
2.46 |
0.26 |
2.34e-14 |
| Female |
0.26 |
-0.06 |
0.59 |
0.17 |
0.11 |
| Non-binary/Self-defined |
0.76 |
-0.17 |
1.68 |
0.47 |
0.11 |
| age_category_collapsed_reordered16-18 |
2.33 |
1.59 |
3.06 |
0.37 |
5.44e-10 |
| 19-25 years |
1.32 |
0.89 |
1.74 |
0.22 |
1.46e-09 |
| 36-45 years |
-0.53 |
-0.92 |
-0.14 |
0.20 |
0.007 |
| 46-55 years |
-0.85 |
-1.22 |
-0.48 |
0.19 |
7.61e-06 |
| 56-65 years |
-1.33 |
-1.79 |
-0.87 |
0.23 |
1.33e-08 |
| 66-70 years |
-2.64 |
-3.44 |
-1.85 |
0.40 |
6.08e-11 |
| 71-75 years |
-3.38 |
-4.35 |
-2.41 |
0.50 |
1.00e-11 |
| 76+ years |
-3.21 |
-4.90 |
-1.52 |
0.86 |
2.02e-04 |
| Mixed or multiple ethnic origins |
-0.08 |
-0.93 |
0.76 |
0.43 |
0.85 |
| Asian or Asian British |
0.17 |
-1.18 |
1.52 |
0.69 |
0.81 |
| African or African British |
2.39 |
0.28 |
4.50 |
1.08 |
0.03 |
| Other ethnicity |
0.22 |
-1.07 |
1.50 |
0.66 |
0.74 |
| Key worker |
0.16 |
-0.40 |
0.73 |
0.29 |
0.57 |
| Time difference: Lockdown to baseline |
0.13 |
0.05 |
0.20 |
0.04 |
0.001 |
| 11081 |
0.02 |
0.02 |
32.92 |
1.45e-39 |
6 |
Sensitivity based on GLAD sign up
#PCL prepan: sensitivity ## Regression: Absolute scores ### Model 1b: Overlapping disorders, Adjusted Model 0a + Gender_collapsed + age_category_collapsed_reordered + Ethnicity_collapsed + Time registration and baseline #### Subset of participants 3 months prior to pandemic
| Intercept |
5.43 |
2.81 |
8.04 |
1.33 |
5.11e-05 |
| pcl.sum_score_prepan |
0.60 |
0.54 |
0.66 |
0.03 |
2.45e-65 |
| Depressive and anxiety disorder |
0.71 |
-1.02 |
2.44 |
0.88 |
0.42 |
| Only depressive disorder |
-0.49 |
-2.36 |
1.38 |
0.95 |
0.61 |
| Only anxiety disorder |
0.53 |
-1.56 |
2.62 |
1.06 |
0.62 |
| Eating disorders |
0.53 |
-0.56 |
1.62 |
0.56 |
0.34 |
| OCDs |
0.05 |
-1.06 |
1.17 |
0.57 |
0.93 |
| Psychotic and bipolar disorder |
0.79 |
-1.85 |
3.44 |
1.35 |
0.56 |
| Only psychotic disorder |
-0.95 |
-3.68 |
1.77 |
1.39 |
0.49 |
| Only bipolar disorder |
-0.24 |
-2.01 |
1.53 |
0.90 |
0.79 |
| PTSD |
1.07 |
0.00 |
2.13 |
0.54 |
0.05 |
| ASD |
-0.01 |
-1.96 |
1.93 |
0.99 |
0.99 |
| ADHD |
-1.49 |
-4.15 |
1.18 |
1.36 |
0.27 |
| Personality disorder |
0.11 |
-1.28 |
1.49 |
0.71 |
0.88 |
| Female |
0.50 |
-0.41 |
1.41 |
0.46 |
0.28 |
| Non-binary/Self-defined |
2.84 |
-0.61 |
6.29 |
1.76 |
0.11 |
| age_category_collapsed_reordered16-18 |
0.81 |
-1.14 |
2.77 |
1.00 |
0.42 |
| 19-25 years |
-0.49 |
-1.82 |
0.85 |
0.68 |
0.47 |
| 36-45 years |
-1.25 |
-2.37 |
-0.13 |
0.57 |
0.03 |
| 46-55 years |
-0.59 |
-1.70 |
0.53 |
0.57 |
0.30 |
| 56-65 years |
-0.72 |
-1.89 |
0.45 |
0.59 |
0.23 |
| 66-70 years |
-2.28 |
-4.34 |
-0.22 |
1.05 |
0.03 |
| 71-75 years |
-1.90 |
-4.84 |
1.04 |
1.50 |
0.20 |
| 76+ years |
-1.04 |
-4.67 |
2.59 |
1.85 |
0.58 |
| Mixed or multiple ethnic origins |
-2.09 |
-4.46 |
0.28 |
1.21 |
0.08 |
| Asian or Asian British |
0.42 |
-3.67 |
4.50 |
2.08 |
0.84 |
| African or African British |
-0.02 |
-4.49 |
4.45 |
2.28 |
0.99 |
| Other ethnicity |
-1.32 |
-5.74 |
3.11 |
2.25 |
0.56 |
| Key worker |
0.16 |
-0.61 |
0.92 |
0.39 |
0.68 |
| Time difference: Lockdown to baseline |
0.07 |
-0.11 |
0.25 |
0.09 |
0.45 |
| 818 |
0.02 |
0.01 |
2.54 |
0.02 |
6 |
Subset of participants 6 months prior to pandemic
| Intercept |
4.85 |
3.04 |
6.65 |
0.92 |
1.59e-07 |
| pcl.sum_score_prepan |
0.61 |
0.56 |
0.65 |
0.02 |
1.72e-141 |
| Depressive and anxiety disorder |
1.22 |
0.10 |
2.34 |
0.57 |
0.03 |
| Only depressive disorder |
0.10 |
-1.13 |
1.33 |
0.63 |
0.87 |
| Only anxiety disorder |
0.46 |
-0.90 |
1.81 |
0.69 |
0.51 |
| Eating disorders |
0.87 |
0.10 |
1.64 |
0.39 |
0.03 |
| OCDs |
0.55 |
-0.19 |
1.28 |
0.37 |
0.14 |
| Psychotic and bipolar disorder |
-0.17 |
-2.26 |
1.92 |
1.07 |
0.88 |
| Only psychotic disorder |
0.00 |
-1.62 |
1.62 |
0.83 |
1.00 |
| Only bipolar disorder |
-0.06 |
-1.17 |
1.05 |
0.57 |
0.91 |
| PTSD |
0.84 |
0.11 |
1.56 |
0.37 |
0.02 |
| ASD |
-0.54 |
-1.96 |
0.88 |
0.72 |
0.46 |
| ADHD |
-0.47 |
-2.13 |
1.19 |
0.85 |
0.58 |
| Personality disorder |
0.53 |
-0.44 |
1.49 |
0.49 |
0.29 |
| Female |
0.59 |
-0.04 |
1.22 |
0.32 |
0.07 |
| Non-binary/Self-defined |
0.96 |
-1.06 |
2.97 |
1.03 |
0.35 |
| age_category_collapsed_reordered16-18 |
0.98 |
-0.21 |
2.17 |
0.61 |
0.11 |
| 19-25 years |
-0.66 |
-1.57 |
0.26 |
0.47 |
0.16 |
| 36-45 years |
-1.29 |
-2.07 |
-0.51 |
0.40 |
0.001 |
| 46-55 years |
-0.96 |
-1.73 |
-0.19 |
0.39 |
0.01 |
| 56-65 years |
-0.75 |
-1.57 |
0.07 |
0.42 |
0.07 |
| 66-70 years |
-1.72 |
-3.08 |
-0.35 |
0.70 |
0.01 |
| 71-75 years |
-2.50 |
-4.18 |
-0.83 |
0.85 |
0.003 |
| 76+ years |
-0.28 |
-2.81 |
2.26 |
1.29 |
0.83 |
| Mixed or multiple ethnic origins |
-0.45 |
-2.06 |
1.15 |
0.82 |
0.58 |
| Asian or Asian British |
-0.36 |
-2.61 |
1.89 |
1.15 |
0.75 |
| African or African British |
-0.24 |
-3.83 |
3.36 |
1.83 |
0.90 |
| Other ethnicity |
0.70 |
-1.84 |
3.24 |
1.30 |
0.59 |
| Key worker |
-0.11 |
-0.63 |
0.40 |
0.26 |
0.66 |
| Time difference: Lockdown to baseline |
0.06 |
-0.07 |
0.20 |
0.07 |
0.37 |
| 1617 |
0.01 |
0.01 |
3.89 |
7.39e-04 |
6 |
Subset of participants 9 months prior to pandemic
| Intercept |
6.36 |
4.93 |
7.79 |
0.73 |
3.92e-18 |
| pcl.sum_score_prepan |
0.58 |
0.55 |
0.62 |
0.02 |
3.48e-216 |
| Depressive and anxiety disorder |
0.85 |
-0.04 |
1.74 |
0.46 |
0.06 |
| Only depressive disorder |
-0.02 |
-0.99 |
0.95 |
0.49 |
0.97 |
| Only anxiety disorder |
-0.15 |
-1.23 |
0.94 |
0.55 |
0.79 |
| Eating disorders |
0.57 |
-0.04 |
1.17 |
0.31 |
0.07 |
| OCDs |
0.50 |
-0.07 |
1.07 |
0.29 |
0.09 |
| Psychotic and bipolar disorder |
-0.76 |
-2.31 |
0.79 |
0.79 |
0.34 |
| Only psychotic disorder |
0.56 |
-0.71 |
1.83 |
0.65 |
0.39 |
| Only bipolar disorder |
-0.02 |
-0.87 |
0.84 |
0.44 |
0.96 |
| PTSD |
0.82 |
0.27 |
1.37 |
0.28 |
0.003 |
| ASD |
-0.52 |
-1.64 |
0.59 |
0.57 |
0.36 |
| ADHD |
-0.14 |
-1.51 |
1.23 |
0.70 |
0.84 |
| Personality disorder |
1.14 |
0.40 |
1.88 |
0.38 |
0.003 |
| Female |
0.38 |
-0.10 |
0.85 |
0.24 |
0.12 |
| Non-binary/Self-defined |
0.49 |
-1.00 |
1.99 |
0.76 |
0.52 |
| age_category_collapsed_reordered16-18 |
0.80 |
-0.24 |
1.83 |
0.53 |
0.13 |
| 19-25 years |
-0.19 |
-0.91 |
0.53 |
0.37 |
0.61 |
| 36-45 years |
-0.87 |
-1.47 |
-0.27 |
0.31 |
0.005 |
| 46-55 years |
-0.87 |
-1.45 |
-0.29 |
0.30 |
0.003 |
| 56-65 years |
-1.00 |
-1.63 |
-0.38 |
0.32 |
0.002 |
| 66-70 years |
-1.64 |
-2.66 |
-0.63 |
0.52 |
0.002 |
| 71-75 years |
-1.87 |
-3.14 |
-0.60 |
0.65 |
0.004 |
| 76+ years |
-0.98 |
-3.15 |
1.20 |
1.11 |
0.38 |
| Mixed or multiple ethnic origins |
0.50 |
-0.86 |
1.87 |
0.70 |
0.47 |
| Asian or Asian British |
-0.14 |
-1.88 |
1.61 |
0.89 |
0.88 |
| African or African British |
2.29 |
-0.44 |
5.03 |
1.40 |
0.10 |
| Other ethnicity |
0.52 |
-1.21 |
2.26 |
0.89 |
0.55 |
| Key worker |
-0.34 |
-0.73 |
0.06 |
0.20 |
0.09 |
| Time difference: Lockdown to baseline |
-0.04 |
-0.14 |
0.07 |
0.06 |
0.52 |
| 2689 |
0.02 |
0.02 |
9.07 |
7.69e-10 |
6 |